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Company ReportsHalozyme Therapeutics

Halozyme Therapeutics(HALO)

Halozyme Therapeutics is an American biotechnology company that develops novel oncology therapies designed to target the tumor microenvironment and licenses a novel drug delivery technology through corporate partnerships.

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Financial

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Hylenex recombinant	Hyaluronidase human	2005-12-02		Rheumatoid arthritis , Mantle-cell lymphoma , B-cell lymphoma , Lymphoid leukemia , Granulomatosis with polyangiitis , Microscopic polyangiitis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Hyaluronidase (human recombinant)

myeloid leukemia acute

,

myeloid leukemia

,

cholangiocarcinoma

,

monocytic leukemia acute

,

castleman disease

,

burkitt lymphoma

,

multiple sclerosis

,

,

stomach neoplasms

,

hypercholesterolemia

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

myelodysplastic syndromes

,

primary myelofibrosis

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

,

,

pancreatic neoplasms

,

,

non-hodgkin lymphoma

,

,

,

b-cell lymphoma marginal zone

,

male breast neoplasms

,

alzheimer disease

,

type 2 diabetes mellitus

,

large b-cell lymphoma diffuse

,

b-cell chronic lymphocytic leukemia

,

hereditary angioedemas

,

,

urinary bladder neoplasms

,

hematologic neoplasms

,

prostatic neoplasms

,

hodgkin disease

,

esophageal neoplasms

,

,

cutaneous malignant melanoma

,

neoplasms by site

,

lymphoid leukemia

,

muscle spasticity

,

,

,

allergic contact dermatitis

,

,

contact dermatitis

,

triple negative breast neoplasms

,

heart transplantation

,

urologic neoplasms

,

transitional cell carcinoma

,

castration-resistant prostatic neoplasms

,

peripheral nervous system diseases

,

paraproteinemias

,

polyneuropathies

,

monoclonal gammopathy of undetermined significance

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

,

,

b-cell lymphoma

,

non-small-cell lung carcinoma

,

,

,

follicular lymphoma

,

,

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

polyradiculoneuropathy

,

pancreatic ductal carcinoma

,

mantle-cell lymphoma

,

,

immunoglobulin light-chain amyloidosis

,

,

bullous pemphigoid

,

,

dermatomyositis

,

muscular diseases

,

,

smoldering multiple myeloma

,

renal cell carcinoma

,

ductal carcinoma

,

residual neoplasm

,

,

endometrial neoplasms

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

,

acinar cell carcinoma

,

mullerian mixed tumor

,

inflammatory breast neoplasms

,

healthy volunteers/patients

,

immunologic deficiency syndromes

,

primary immunodeficiency diseases

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

,

rheumatoid arthritis

,

,

,

,

stiff-person syndrome

,

neoplasm metastasis

,

,

pneumococcal pneumonia

,

invasive hydatidiform mole

,

,

pain management

,

,

,

rectal neoplasms

Hyaluronate sodium

,

capsule opacification

,

phacoemulsification

,

,

dry eye syndromes

,

keratoconjunctivitis sicca

,

pancreatic neoplasms

,

Polytetrafluoroethylene

dental implants

,

soft tissue injuries

,

urinary bladder neoplasms

,

diabetes mellitus

,

,

chronic kidney failure

,

renal insufficiency

,

liver cirrhosis

,

tissue adhesions

,

,

,

,

radiation injuries

,

pleural effusion

,

malignant pleural effusion

,

vocal cord paralysis

,

,

anatomical pathological conditions

,

kidney diseases

,

chronic renal insufficiency

,

,

alveolar bone loss

,

,

peri-implantitis

,

peripheral nerve injuries

,

pyloric stenosis

,

gastric outlet obstruction

,

periodontal diseases

,

,

,

,

,

chronic limb-threatening ischemia

,

peripheral catheterization

,

inguinal hernia

,

acute coronary syndrome

,

,

,

,

,

postoperative complications

,

,

wound infection

,

intermittent claudication

,

,

type 1 diabetes mellitus

,

,

,

,

tooth extraction

,

tissue preservation

,

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

aortic dissection

,

wounds and injuries

,

,

communicable diseases

,

portal hypertension

,

gastrointestinal hemorrhage

,

,

,

,

,

biliary tract neoplasms

,

pathologic constriction

,

pelvic organ prolapse

,

,

,

vascular diseases

,

aortic aneurysm

,

aortic diseases

,

,

aortic arch syndromes

,

,

,

,

,

post-dural puncture headache

,

,

,

sprains and strains

,

premature birth

,

schistosomiasis

,

schistosomiasis mansoni

,

incisional hernia

,

,

alveolar ridge augmentation

,

edentulous mouth

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

gastroesophageal reflux

,

drug-related side effects and adverse reactions

,

gingival pocket

,

joint instability

,

,

bone resorption

,

,

,

,

vascular grafting

,

wound closure techniques

,

uterine prolapse

,

,

cardiovascular diseases

,

mitral valve insufficiency

,

arteriovenous fistula

,

mesenteric ischemia

,

arteriosclerosis

,

,

,

cholangiocarcinoma

,

biliary tract diseases

,

ampulla of vater cancer

,

,

,

colonic diverticulosis

,

colon diverticulum

,

,

coronary stenosis

,

,

,

,

atrophic rhinitis

,

,

cystic fibrosis

,

abdominal aortic aneurysm

,

,

dental implantation

,

single-tooth dental implants

,

immunohistochemistry

,

,

tooth fractures

,

surgical blood loss

,

,

bacterial endocarditis

,

,

congenital abnormalities

,

congenital heart defects

,

heart septal defects

,

ventricular heart septal defects

,

aortic valve insufficiency

,

ascending aorta dissection

,

nephrolithiasis

,

,

,

dental enamel hypoplasia

,

urinary incontinence

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

,

venous thrombosis

,

bacterial infections

multiple myeloma

,

plasma cell neoplasms

,

squamous cell carcinoma of head and neck

,

,

head and neck neoplasms

,

,

breast neoplasms

,

triple negative breast neoplasms

,

squamous cell neoplasms

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

neoplasm metastasis

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

colorectal neoplasms

,

renal cell carcinoma

,

endometrial neoplasms

,

small cell carcinoma

,

uterine cervical neoplasms

,

urologic neoplasms

,

,

cutaneous malignant melanoma

,

pancreatic neoplasms

,

stomach neoplasms

,

rectal neoplasms

,

thyroid neoplasms

,

,

,

neuroendocrine carcinoma

,

,

brain stem neoplasms

,

medullary carcinoma

,

phenylketonurias

,

follicular lymphoma

,

brain neoplasms

,

,

microsatellite instability

,

tertiary lymphoid structures

,

,

non-small-cell lung carcinoma

,

,

,

squamous cell carcinoma

,

small cell lung carcinoma

,

esophageal neoplasms

,

liver neoplasms

,

esophageal squamous cell carcinoma

,

hepatocellular carcinoma

healthy volunteers/patients

,

metabolic diseases

,

metabolic syndrome

,

lipid metabolism disorders

,

hypercholesterolemia

,

,

hyperlipidemias

,

hyperlipoproteinemias

,

cardiovascular diseases

,

hyperlipoproteinemia type ii

,

autistic disorder

,

phenylketonurias

,

duchenne muscular dystrophy

,

muscular dystrophies

,

Vorhyaluronidase alfa

hereditary angioedemas

,

Sodium chloride

C1 esterase inhibitor

renal insufficiency

,

graft rejection

,

hereditary angioedemas

,

Alunacedase alfa

,

healthy volunteers/patients

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

wounds and injuries

,

acute lung injury

,

pancreatic neoplasms

,

inflammatory bowel diseases

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

renal insufficiency

,

brain neoplasms

,

glandular and epithelial neoplasms

,

,

delayed graft function

,

hypersensitivity

,

venous thromboembolism

,

thromboembolism

,

pharmacokinetics

,

,

central nervous system diseases

,

,

,

endometrial neoplasms

,

,

mullerian mixed tumor

,

,

,

breast neoplasms

,

rheumatoid arthritis

,

,

b-cell chronic lymphocytic leukemia

,

neoplasm metastasis

,

,

non-hodgkin lymphoma

,

,

colorectal neoplasms

,

ulcerative colitis

,

,

,

,

triple negative breast neoplasms

,

small cell lung carcinoma

,

autoimmune diseases

,

,

kidney neoplasms

,

,

female genital neoplasms

,

biliary tract neoplasms

,

neuroendocrine tumors

,

,

kidney transplantation

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

,

lipoid nephrosis

,

discoid lupus erythematosus

,

cutaneous lupus erythematosus

,

lupus nephritis

,

,

,

diabetic nephropathies

,

kidney diseases

,

atopic dermatitis

,

,

,

alopecia areata

,

,

hematologic neoplasms

,

gastrointestinal neoplasms

,

esophageal neoplasms

,

pancreatic ductal carcinoma

,

hidradenitis suppurativa

,

,

polycythemia vera

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

gastrointestinal stromal tumors

,

,

alveolar soft part sarcoma

,

solitary fibrous tumors

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors peripheral

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

giant cell tumor of bone

,

giant cell tumors

,

hemangiopericytoma

,

adenocarcinoma of lung

,

merkel cell carcinoma

,

castration-resistant prostatic neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

non-small-cell lung carcinoma

,

,

renal cell carcinoma

,

systemic lupus erythematosus

,

lymphoid leukemia

,

multiple myeloma

,

philadelphia chromosome

,

prostatic neoplasms

,

,

plasma cell neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

psoriatic arthritis

,

hepatocellular carcinoma

,

liver neoplasms

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

,

myeloid leukemia accelerated phase

,

sjogren's syndrome

,

squamous cell carcinoma

,

rheumatic diseases

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

healthy volunteers/patients

,

,

myeloid leukemia chronic-phase

,

coronary artery disease

,

pleural effusion

,

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

alzheimer disease

,

progressive supranuclear palsy

,

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

Pegvorhyaluronidase alfa

non-small-cell lung carcinoma

,

,

cholangiocarcinoma

,

,

stomach neoplasms

,

pancreatic neoplasms

,

esophageal neoplasms

,

breast neoplasms

,

,

pancreatic ductal carcinoma

,

ductal carcinoma

duchenne muscular dystrophy

,

muscular dystrophies

,

growth disorders

,

failure to thrive

,

,

,

,

,

insulin resistance

,

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