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Halozyme Therapeutics
Halozyme Therapeutics
(HALO)
Halozyme Therapeutics is an American biotechnology company that develops novel oncology therapies designed to target the tumor microenvironment and licenses a novel drug delivery technology through corporate partnerships.
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Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Hylenex recombinant
Hyaluronidase (human recombinant)
2005-12-02
Rheumatoid arthritis
,
Mantle-cell lymphoma
,
B-cell lymphoma
,
Lymphoid leukemia
,
Granulomatosis with polyangiitis
,
Microscopic polyangiitis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Hyaluronidase (human recombinant)
lung neoplasms
,
urinary bladder neoplasms
,
liver neoplasms
,
kidney neoplasms
,
neoplasms
,
neoplasms by site
,
urologic neoplasms
,
transitional cell carcinoma
,
neoplasm metastasis
,
patient preference
,
multiple myeloma
,
plasma cell neoplasms
,
melanoma
,
skin neoplasms
,
renal cell carcinoma
Hyaluronate sodium
erythema
,
acne vulgaris
,
keratoconjunctivitis sicca
,
dry eye syndromes
,
cataract
Polytetrafluoroethylene
dental implants
,
soft tissue injuries
,
urinary incontinence
,
urinary bladder neoplasms
,
urinary retention
,
spinal cord injuries
,
chronic kidney failure
,
atrophy
,
renal insufficiency
,
tissue adhesions
,
psoriasis
,
kidney diseases
,
proctitis
,
telangiectasis
,
radiation injuries
,
malignant pleural effusion
,
vocal cord paralysis
,
paralysis
,
anatomical pathological conditions
,
chronic renal insufficiency
,
hyperplasia
,
alveolar bone loss
,
peri-implantitis
,
atherosclerosis
,
edentulous mouth
,
hiatal hernia
,
bone resorption
,
periodontitis
,
peripheral nerve injuries
,
pyloric stenosis
,
gastric outlet obstruction
,
periodontal diseases
,
hyperemia
,
metabolic bone diseases
,
osteoporosis
,
jaw fractures
,
edentulous jaw
,
adenocarcinoma
,
peritoneal neoplasms
,
vascular diseases
,
peripheral arterial disease
,
hernia
,
ischemia
,
diabetes mellitus
,
fibrosis
,
arterial occlusive diseases
,
peripheral vascular diseases
,
tooth loss
,
liver cirrhosis
,
chronic limb-threatening ischemia
,
hemorrhage
,
intermittent claudication
,
pancreatic neoplasms
,
gastrointestinal hemorrhage
,
bile duct neoplasms
,
peripheral catheterization
,
inguinal hernia
,
acute coronary syndrome
,
syndrome
,
hemostasis
,
dehydration
,
anodontia
,
ventral hernia
,
recurrence
,
postoperative complications
,
pain
,
wound infection
,
brain diseases
,
dental enamel hypoplasia
,
hypertension
,
portal hypertension
,
inflammation
,
pathologic constriction
,
aneurysm
,
aortic dissection
,
type 1 diabetes mellitus
,
heart failure
,
tooth extraction
,
tissue preservation
,
ascites
,
prolapse
,
fistula
,
congenital heart defects
,
heart diseases
,
aortic aneurysm
,
aortic diseases
,
infections
,
communicable diseases
,
mitral valve insufficiency
,
incisional hernia
,
mucositis
,
alveolar ridge augmentation
,
cardiomyopathies
,
rupture
,
blepharoptosis
,
biliary tract neoplasms
,
pelvic organ prolapse
,
renal dialysis
,
disease
,
cholangiocarcinoma
,
soft tissue infections
,
bone density
,
dental caries
,
otosclerosis
,
heart septal defects
,
aortic arch syndromes
,
nephrolithiasis
,
kidney calculi
,
traumatic brain injuries
,
brain injuries
,
otitis media
,
otitis
,
post-dural puncture headache
,
endoscopy
,
ankle injuries
,
sprains and strains
,
premature birth
,
schistosomiasis
,
schistosomiasis mansoni
,
neoplasms
,
pancreatitis
,
hysterectomy
,
dilated cardiomyopathy
,
gastroesophageal reflux
,
drug-related side effects and adverse reactions
,
gingival pocket
,
joint instability
,
reinjuries
,
aphasia
,
aphakia
,
wounds and injuries
,
hemolysis
,
vascular grafting
,
wound closure techniques
,
uterine prolapse
,
cystocele
,
cardiovascular diseases
,
arteriovenous fistula
,
mesenteric ischemia
,
arteriosclerosis
,
necrosis
,
biliary tract diseases
,
ampulla of vater cancer
,
angiodysplasia
,
colonic polyps
,
colonic diverticulosis
,
colon diverticulum
,
diverticulum
,
coronary stenosis
,
bacteremia
,
vascular ring
,
rhinitis
,
atrophic rhinitis
,
bone regeneration
,
surgical wound
,
surgical wound dehiscence
,
corneal ulcer
,
bile duct diseases
,
intracranial aneurysm
,
carotid-cavernous sinus fistula
,
periodontal debridement
,
long qt syndrome
,
ventricular tachycardia
,
tachycardia
,
ventricular fibrillation
,
arteritis
,
liver diseases
,
cystic fibrosis
,
abdominal aortic aneurysm
,
dental implantation
,
single-tooth dental implants
,
immunohistochemistry
,
tooth fractures
,
surgical blood loss
,
electrosurgery
,
obesity
,
bacterial endocarditis
,
endocarditis
,
congenital abnormalities
,
ventricular heart septal defects
,
aortic valve stenosis
,
bone transplantation
,
atrial heart septal defects
,
aortic valve insufficiency
,
ascending aorta dissection
,
hypertrophy
,
calculi
,
menopause
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
thrombosis
,
venous thrombosis
,
bacterial infections
,
percutaneous nephrolithotomy
,
oral surgery
,
virus diseases
,
color
,
breast neoplasms
,
breast carcinoma in situ
Tiragolumab
neoplasm metastasis
,
multiple myeloma
,
squamous cell carcinoma of head and neck
,
squamous cell neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
head and neck neoplasms
,
colorectal neoplasms
,
melanoma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
adenocarcinoma
,
non-hodgkin lymphoma
,
b-cell lymphoma
,
renal cell carcinoma
,
recurrence
,
endometrial neoplasms
,
small cell carcinoma
,
uterine cervical neoplasms
,
urologic neoplasms
,
pancreatic neoplasms
,
stomach neoplasms
,
rectal neoplasms
,
sarcoma
,
rhabdoid tumor
,
chordoma
,
brain stem neoplasms
,
phenylketonurias
,
lymphoma
,
follicular lymphoma
,
brain neoplasms
,
glioblastoma
,
microsatellite instability
,
tertiary lymphoid structures
,
spinocerebellar degenerations
,
non-small-cell lung carcinoma
,
carcinoma
,
neoplasms
,
squamous cell carcinoma
,
lung neoplasms
,
small cell lung carcinoma
,
esophageal neoplasms
,
liver neoplasms
,
esophageal squamous cell carcinoma
,
hepatocellular carcinoma
Gilvetmab
lung neoplasms
,
small cell lung carcinoma
,
neoplasms
,
melanoma
,
urinary bladder neoplasms
,
esophageal squamous cell carcinoma
,
triple negative breast neoplasms
,
malignant mesothelioma
,
breast neoplasms
,
glioblastoma
,
colorectal neoplasms
,
pancreatic neoplasms
,
tumor virus infections
,
non-small-cell lung carcinoma
Bococizumab
healthy volunteers/patients
,
metabolic diseases
,
metabolic syndrome
,
lipid metabolism disorders
,
hypercholesterolemia
,
dyslipidemias
,
hyperlipidemias
,
hyperlipoproteinemias
,
cardiovascular diseases
,
hyperlipoproteinemia type ii
Maxacalcitol
esophageal neoplasms
Edrecolomab
hypertension
,
hiv infections
,
hiv
,
acquired immunodeficiency syndrome
,
immunologic deficiency syndromes
,
neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
transitional cell carcinoma
,
breast neoplasms
,
renal cell carcinoma
,
urologic neoplasms
,
carcinoma
,
stomach neoplasms
,
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
melanoma
,
squamous cell carcinoma
,
mouth neoplasms
,
oropharyngeal neoplasms
,
squamous cell neoplasms
,
neoplasms by histologic type
,
neoplasms by site
,
glandular and epithelial neoplasms
,
hypopharyngeal neoplasms
,
hepatitis c
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
malignant mesothelioma
,
mesothelioma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
pancreatic ductal carcinoma
,
biliary tract neoplasms
,
invasive hydatidiform mole
Doconexent
myeloid leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
biphenotypic leukemia acute
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
Aspartame
healthy volunteers/patients
,
colorectal neoplasms
,
chronic renal insufficiency
,
kidney diseases
,
sickle cell anemia
,
knee osteoarthritis
,
osteoarthritis
,
heart failure
,
lung neoplasms
,
ovarian neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
head and neck neoplasms
,
squamous cell carcinoma
,
squamous cell neoplasms
,
laryngeal neoplasms
,
opioid-related disorders
,
covid-19
,
coronavirus infections
,
carcinoma
,
neoplasms
,
urinary bladder neoplasms
,
brain neoplasms
,
serous cystadenocarcinoma
,
glioma
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
body weight
,
cystic fibrosis
,
melanoma
,
biliary tract neoplasms
,
rare diseases
,
invasive hydatidiform mole
,
non-muscle invasive bladder neoplasms
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
mantle-cell lymphoma
,
b-cell lymphoma
,
b-cell leukemia
,
diabetes mellitus
,
chronic obstructive pulmonary disease
,
obesity
,
lung diseases
,
obstructive lung diseases
,
non-small-cell lung carcinoma
,
asthma
,
pulmonary eosinophilia
,
overweight
,
weight loss
,
hyperkalemia
,
endometrial neoplasms
,
borderline personality disorder
,
personality disorders
,
churg-strauss syndrome
,
eosinophilic granuloma
,
type 2 diabetes mellitus
,
breast neoplasms
,
fibrosis
,
inflammation
,
myocarditis
,
endomyocardial fibrosis
,
postoperative pain
,
depression
,
major depressive disorder
,
depressive disorder
Bevifimod
brain neoplasms
,
nutritional status
,
pneumonia
,
pneumococcal pneumonia
,
obesity
,
male breast neoplasms
,
respiratory tract infections
,
embryo transfer
,
hyperalgesia
,
epilepsy
,
blister
,
postpartum hemorrhage
,
inflammatory bowel diseases
,
virus diseases
,
tendon injuries
,
dermatitis
,
community-acquired infections
,
haemophilus influenzae
,
streptococcus pneumoniae
,
prostatic neoplasms
,
cytomegalovirus infections
,
crohn disease
,
energy metabolism
,
ovarian epithelial carcinoma
,
head and neck neoplasms
,
stomach neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
neoplasms by site
,
non-small-cell lung carcinoma
,
malaria
,
lung neoplasms
,
falciparum malaria
,
ovarian neoplasms
,
renal cell carcinoma
,
melanoma
,
healthy volunteers/patients
,
colorectal neoplasms
,
arthritis
,
lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
pancreatic neoplasms
,
uterine cervical neoplasms
,
neuralgia
,
type 1 diabetes mellitus
,
sickle cell anemia
,
sjogren's syndrome
,
dyslipidemias
,
inflammation
,
respiration disorders
,
chronic hepatitis b
,
hepatitis
,
endometrial neoplasms
,
carcinoma
,
malignant mesothelioma
,
squamous cell carcinoma of head and neck
,
cutaneous malignant melanoma
,
streptococcus agalactiae
,
follicular lymphoma
,
microsatellite repeats
,
small cell lung carcinoma
,
macular degeneration
,
b-cell lymphoma
,
sinusitis
,
pre-eclampsia
,
respiratory tract diseases
,
proteinuria
,
focal segmental glomerulosclerosis
,
chronic hepatitis
,
membranous glomerulonephritis
,
nephrotic syndrome
,
endometrioid carcinoma
,
fallopian tube neoplasms
,
systemic scleroderma
,
bone diseases
,
granulomatosis with polyangiitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
xerostomia
,
glioblastoma
,
glioma
,
gliosarcoma
,
kidney transplantation
,
wilms tumor
,
contraception
,
hypogonadism
,
b-cell chronic lymphocytic leukemia
,
beta-thalassemia
,
thalassemia
,
sickle cell trait
,
ulcer
,
buruli ulcer
,
clear cell adenocarcinoma
,
large cell carcinoma
,
vaginal neoplasms
,
vulvar neoplasms
,
adenomyoepithelioma
,
breast neoplasms
,
neoplasms
,
rheumatoid arthritis
,
covid-19
,
haemophilus influenzae type b
,
haemophilus infections
,
chronic renal insufficiency
,
anemia
,
neisseria meningitidis
,
respiratory syncytial virus infections
,
streptococcal infections
,
hepatitis b
,
muscle spasticity
,
kidney diseases
,
postmenopausal osteoporosis
,
non-hodgkin lymphoma
,
herpes zoster
,
human influenza
,
mumps
,
insulin resistance
,
hepatitis a
,
pneumococcal infections
,
thrombocytopenic purpura idiopathic
,
inflammatory breast neoplasms
,
recurrence
,
ductal carcinoma breast
,
measles
,
rubella
,
abdominal obesity
,
adenocarcinoma
,
strabismus
,
stroke
,
chronic kidney failure
,
bone fractures
,
large b-cell lymphoma diffuse
,
hiv-1
,
renal insufficiency
,
systemic lupus erythematosus
,
myocardial infarction
,
st elevation myocardial infarction
,
acute coronary syndrome
,
syndrome
,
heart failure
,
left ventricular hypertrophy
,
rotavirus infections
,
tetanus
,
diphtheria
,
meningococcal infections
,
otitis media
,
mucinous adenocarcinoma
,
meningitis
,
meningococcal meningitis
,
hemorrhage
,
thrombocytopenia
,
respiratory syncytial viruses
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hiv infections
,
hypertension
,
asthma
,
infections
,
chronic obstructive pulmonary disease
,
acquired immunodeficiency syndrome
,
osteoporosis
,
psoriasis
,
lung diseases
,
nausea
,
metabolic bone diseases
,
obstructive lung diseases
,
pulmonary eosinophilia
,
hypothyroidism
,
lipodystrophy
,
chronic bronchitis
,
bronchitis
,
chronic disease
,
growth and development
,
dysphonia
,
skin diseases
,
immunologic tests
,
cognition
,
alzheimer disease
,
cardiovascular diseases
,
wasting syndrome
,
cachexia
,
lipid metabolism
,
resistance training
,
exercise
,
depression
,
major depressive disorder
,
depressive disorder
,
rhinitis
,
allergic rhinitis seasonal
,
clostridioides difficile
Doxecitine
b-cell lymphoma
,
glioma
,
liver neoplasms
,
unknown primary neoplasms
,
nasopharyngeal neoplasms
,
esophageal neoplasms
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
hepatocellular carcinoma
,
brain stem neoplasms
,
brain neoplasms
,
hodgkin disease
,
aids-related lymphoma
,
extranodal nk-t-cell lymphoma
,
recurrence
,
clear cell adenocarcinoma
,
invasive hydatidiform mole
,
bile duct neoplasms
,
gallbladder neoplasms
,
erythema multiforme
,
hiv infections
,
stomach neoplasms
,
acquired immunodeficiency syndrome
,
aids-related complex
,
neoplasms
,
neoplasm metastasis
,
adenocarcinoma
,
lymphoma
,
transitional cell carcinoma
,
large b-cell lymphoma diffuse
,
urologic neoplasms
,
urinary bladder neoplasms
,
head and neck neoplasms
,
ovarian neoplasms
,
non-hodgkin lymphoma
,
triple negative breast neoplasms
,
chronic hepatitis
,
carcinoma
,
lung neoplasms
,
neoplasms by site
,
ductal carcinoma breast
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
neoplasms by histologic type
,
nerve tissue neoplasms
,
kidney diseases
,
aids-associated nephropathy
,
ovarian epithelial carcinoma
,
lobular carcinoma
,
skin diseases
,
breast diseases
,
breast neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
pancreatic neoplasms
,
rectal neoplasms
,
colonic neoplasms
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
Nadide
skin diseases
,
papulosquamous skin diseases
Nepidermin
neurofibromatosis 1
,
hereditary sensory and autonomic neuropathies
,
obesity
,
atopic dermatitis
,
dermatitis
,
liposarcoma
,
ovarian neoplasms
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
esophageal neoplasms
,
esophageal squamous cell carcinoma
,
germ cell and embryonal neoplasms
,
teratoma
,
testicular neoplasms
,
pelvic pain
,
brain neoplasms
,
breast neoplasms
,
neoplasms
,
melanoma
,
colorectal neoplasms
,
type 2 diabetes mellitus
,
neoplasm metastasis
,
infections
,
communicable diseases
,
intraabdominal infections
,
urinary tract infections
,
male breast neoplasms
,
bacterial infections
,
infectious skin diseases
,
wound infection
,
soft tissue infections
,
cellulitis
,
cutaneous malignant melanoma
,
small cell lung carcinoma
,
liver neoplasms
,
recurrence
,
diabetes mellitus
,
hypertension
,
essential hypertension
,
acne vulgaris
,
skin neoplasms
,
skin diseases
,
adenocarcinoma
,
gastrointestinal stromal tumors
,
amyloidosis
,
polyneuropathies
,
familial amyloid neuropathies
,
amyloid neuropathies
,
carcinoma
,
pancreatic neoplasms
,
islet cell carcinoma
,
islet cell adenoma
,
alzheimer disease
,
hiv infections
,
acquired immunodeficiency syndrome
,
leukemia
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
drug therapy
,
myeloid leukemia acute
,
residual neoplasm
,
chronic renal insufficiency
,
kidney diseases
,
acute coronary syndrome
,
syndrome
,
atrial fibrillation
,
drug-related side effects and adverse reactions
,
pain
,
colonic neoplasms
,
rectal neoplasms
,
hand-foot syndrome
,
migraine disorders
,
neuroendocrine tumors
,
non-small-cell lung carcinoma
,
lung neoplasms
Pegvorhyaluronidase alfa
esophageal neoplasms
,
pancreatic neoplasms
,
adenocarcinoma
1
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