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Company ReportsHalozyme Therapeutics

Halozyme Therapeutics(HALO)

Halozyme Therapeutics is an American biotechnology company that develops novel oncology therapies designed to target the tumor microenvironment and licenses a novel drug delivery technology through corporate partnerships.

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Hylenex recombinant	Hyaluronidase (human recombinant)	2005-12-02		Rheumatoid arthritis , Mantle-cell lymphoma , B-cell lymphoma , Lymphoid leukemia , Granulomatosis with polyangiitis , Microscopic polyangiitis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Hyaluronidase (human recombinant)

healthy volunteers/patients

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

aplastic anemia

,

alzheimer disease

,

heart transplantation

,

immunoglobulin light-chain amyloidosis

,

plasma cell neoplasms

,

non-small-cell lung carcinoma

,

smoldering multiple myeloma

,

multiple myeloma

Hyaluronate sodium

,

carpal tunnel syndrome

,

open-angle glaucoma

,

gingival overgrowth

,

,

gingival hyperplasia

,

gingival hypertrophy

,

dental pulp diseases

,

,

stomach neoplasms

,

striae distensae

,

stomatognathic diseases

,

low-level light therapy

,

non-small-cell lung carcinoma

,

,

,

intra-articular injections

,

,

respiratory tract diseases

,

respiration disorders

,

alcoholic hepatitis

,

thyroid neoplasms

,

,

,

cartilage diseases

,

rotator cuff injuries

,

,

urinary bladder neoplasms

,

diabetic retinopathy

,

congenital abnormalities

,

,

patellofemoral pain syndrome

,

corneal diseases

,

somatoform disorders

,

,

,

lower urinary tract symptoms

,

,

oxidative stress

,

,

head and neck neoplasms

,

,

,

conjunctival diseases

,

fecal incontinence

,

,

sudden hearing loss

,

multiple myeloma

,

plasma cell neoplasms

,

carcinoma in situ

,

,

non-muscle invasive bladder neoplasms

,

urinary incontinence

,

parkinson disease

,

,

obstructive lung diseases

,

cartilage fractures

,

,

interstitial lung diseases

,

stress urinary incontinence

,

stem cell research

,

noise-induced hearing loss

,

meniere disease

,

large b-cell lymphoma diffuse

,

papillary carcinoma

,

pancreatic neoplasms

,

spinal cord injuries

,

bacterial conjunctivitis

,

male breast neoplasms

,

,

squamous cell carcinoma of head and neck

,

voice disorders

,

laryngeal neoplasms

,

hereditary corneal dystrophies

,

,

arterial occlusive diseases

,

chronic limb-threatening ischemia

,

,

alpha 1-antitrypsin deficiency

,

pulmonary emphysema

,

,

,

,

sprains and strains

,

,

multiple endocrine neoplasia type 1

,

facial paralysis

,

,

pulmonary hypertension

,

hidradenitis suppurativa

,

,

basal cell carcinoma

,

basal cell neoplasms

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

intratympanic injection

,

,

,

type 2 diabetes mellitus

,

periodontal diseases

,

intervertebral disc degeneration

,

interstitial cystitis

,

,

,

capsule opacification

,

trigger finger disorder

,

shoulder impingement syndrome

,

spontaneous abortion

,

,

,

aphthous stomatitis

,

postoperative pain

,

,

premature birth

,

,

erectile dysfunction

,

colorectal neoplasms

,

,

,

radiodermatitis

,

gingival hemorrhage

,

bone resorption

,

premature ejaculation

,

,

pancreatic ductal carcinoma

,

,

cumulative trauma disorders

,

retinal diseases

,

phacoemulsification

,

,

musculoskeletal diseases

,

,

tendon entrapment

,

,

ductal carcinoma

,

chronic hepatitis c

,

,

,

oral submucous fibrosis

,

,

dental calculus

,

critical illness

,

,

athletic injuries

,

,

,

,

olfactory nerve injuries

,

shoulder injuries

,

retinopathy of prematurity

,

,

prostatic diseases

,

failed back surgery syndrome

,

,

knee osteoarthritis

,

dry eye syndromes

,

keratoconjunctivitis sicca

,

,

,

,

,

wounds and injuries

,

,

tissue adhesions

,

,

,

,

,

,

,

healthy volunteers/patients

,

temporomandibular joint disorders

,

,

gingival recession

,

hip osteoarthritis

,

,

,

,

,

atrophic vaginitis

,

,

,

temporomandibular joint dysfunction syndrome

,

diabetes mellitus

,

breast neoplasms

,

periodontal pocket

,

urinary tract infections

,

,

,

meibomian gland dysfunction

,

,

,

,

,

prostatic neoplasms

,

chronic periodontitis

,

,

alveolar bone loss

,

,

sjogren's syndrome

,

,

,

,

,

keratoconjunctivitis

,

,

,

dental implants

,

,

,

,

,

postoperative complications

,

,

patient satisfaction

,

,

elbow tendinopathy

,

vesico-ureteral reflux

,

,

oral lichen planus

,

,

communicable diseases

,

,

anterior cruciate ligament injuries

,

peri-implantitis

,

,

,

,

allergic conjunctivitis

,

,

chronic obstructive pulmonary disease

,

,

,

,

thyroid diseases

,

,

photorefractive keratectomy

,

male infertility

,

,

,

uterine cervical neoplasms

,

,

beta-thalassemia

,

,

,

injection site reaction

,

,

,

,

induced abortion

,

actinic keratosis

,

,

,

graves ophthalmopathy

,

,

cesarean section

,

obstetric delivery

,

,

alveolar ridge augmentation

,

physiological sexual dysfunction

,

,

sensorineural hearing loss

,

polycystic ovary syndrome

,

,

,

,

procedural pain

,

linear energy transfer

,

,

,

,

depressive disorder

,

re-epithelialization

,

cosmetic techniques

,

uterine diseases

,

retained placenta

,

,

,

intraocular pressure

,

physiological stress

,

breast implantation

,

ethmoid sinusitis

,

,

,

surgical blood loss

,

,

bacterial vaginosis

,

surgical wound dehiscence

,

,

rheumatoid arthritis

,

gastrointestinal diseases

,

intestinal diseases

,

,

breast carcinoma in situ

,

,

gastroesophageal reflux

,

,

vaginal diseases

,

peptic esophagitis

,

,

cataract extraction

,

vocal cord paralysis

,

,

,

retinal detachment

,

,

rectal neoplasms

,

,

intratracheal intubation

,

,

,

venous insufficiency

,

,

,

coronary artery disease

,

spinal stenosis

,

papillomavirus infections

,

,

,

fuchs' endothelial dystrophy

,

furcation defects

,

skin manifestations

,

,

,

femoracetabular impingement

,

intervertebral disc displacement

,

refractive errors

,

,

,

hypertrophic cicatrix

,

dissociative disorders

,

,

phototoxic dermatitis

,

contact dermatitis

,

photoallergic dermatitis

,

,

neuroendocrine tumors

,

penile prosthesis

,

,

,

,

,

endometrial neoplasms

,

retinal vein occlusion

,

,

penile induration

,

endoscopic mucosal resection

,

atopic dermatitis

,

,

myofascial pain syndromes

,

,

,

periodontal attachment loss

,

,

,

,

,

,

patient reported outcome measures

,

disease progression

,

peripheral arterial disease

,

peripheral vascular diseases

,

iron-deficiency anemia

,

iron deficiencies

,

,

viral pneumonia

,

,

coronary disease

,

chondromalacia patellae

,

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

intradermal injections

,

,

hemorrhagic cystitis

,

squamous intraepithelial lesions of the cervix

,

,

male urogenital diseases

,

urogenital diseases

,

,

personal satisfaction

,

,

executive function

,

physical fitness

,

habitual abortion

,

,

,

topical administration

,

endophthalmitis

,

gynecologic surgical procedures

,

precancerous conditions

,

alcoholic liver diseases

,

,

metabolic diseases

,

metabolic syndrome

,

,

high-risk pregnancy

,

stress fractures

,

randomized controlled trials as topic

,

spinal diseases

,

,

,

,

gender dysphoria

,

cerebral infarction

,

,

magnetic resonance angiography

,

,

neurodegenerative diseases

,

,

refractive surgical procedures

,

surgical amputation

,

,

,

,

,

sleep apnea syndromes

,

,

hypersensitivity

,

nociceptive pain

,

,

acute kidney injury

,

,

gastrointestinal microbiome

,

,

fertilization in vitro

,

deglutition disorders

,

,

,

tooth extraction

,

,

,

pleural diseases

,

respiratory system abnormalities

,

cystic fibrosis

,

tibial meniscus injuries

,

open abdomen techniques

,

angle-closure glaucoma

,

embryo implantation

,

corneal transplantation

,

,

,

,

,

central nervous system neoplasms

,

kidney neoplasms

,

,

nervous system neoplasms

,

,

body dysmorphic disorders

,

,

premature aging

,

drug-related side effects and adverse reactions

,

choroid diseases

,

,

dental pulp necrosis

,

,

,

multiple abnormalities

,

pityriasis rubra pilaris

,

,

,

,

,

uterine hemorrhage

,

,

dental pulp exposure

,

metabolic bone diseases

,

afibrinogenemia

,

transitional cell carcinoma

,

corneal opacity

,

nasal obstruction

,

,

muscle spasticity

,

non-alcoholic fatty liver disease

,

,

,

tendon injuries

,

,

prostatic hyperplasia

,

,

,

,

muscle rigidity

,

esophageal neoplasms

,

,

,

sinus floor augmentation

,

,

,

,

,

,

maxillofacial injuries

,

teratozoospermia

,

ventilator-associated pneumonia

,

cross infection

,

healthcare-associated pneumonia

,

,

,

,

,

,

,

suppurative otitis media

,

,

,

dietary supplements

,

,

,

otorhinolaryngologic diseases

,

,

pediatric obesity

,

rheumatic diseases

,

rheumatic fever

,

collagen diseases

,

alphapapillomavirus

,

uterine cervical dysplasia

,

subarachnoid hemorrhage

,

acute lung injury

,

plantar fasciitis

,

,

retinal perforations

,

,

radiofrequency ablation

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

pathologic constriction

,

dentin sensitivity

,

tooth discoloration

,

dental implantation

,

,

hyperpigmentation

,

,

,

,

,

plastic surgery procedures

,

,

general anesthesia

,

vascular malformations

,

,

peripheral nervous system diseases

,

tissue transplantation

,

,

acupuncture therapy

,

,

rotator cuff tear arthropathy

,

premature obstetric labor

Polytetrafluoroethylene

breast neoplasms

,

triple negative breast neoplasms

,

neoplasm metastasis

hypercholesterolemia

,

healthy volunteers/patients

hyperlipidemias

,

,

non-small-cell lung carcinoma

,

,

alzheimer disease

,

myeloid leukemia

,

healthy volunteers/patients

,

ulcerative colitis

,

,

,

rheumatoid arthritis

,

myeloid leukemia acute

,

atopic dermatitis

,

hidradenitis suppurativa

,

,

,

,

pathologic constriction

,

inflammatory bowel diseases

,

intestinal diseases

pharmacokinetics

,

inflammatory breast neoplasms

,

,

renal cell carcinoma

,

communicable diseases

,

pneumococcal infections

,

immune system diseases

,

triple negative breast neoplasms

,

,

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

neoplasm metastasis

,

stomach neoplasms

,

esophageal neoplasms

,

hodgkin disease

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

bronchiolitis obliterans syndrome

,

,

plasma cell neoplasms

,

squamous cell carcinoma of head and neck

,

ovarian epithelial carcinoma

,

human influenza

,

fallopian tube neoplasms

,

biliary tract neoplasms

,

prolymphocytic leukemia

,

pancreatic neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

,

adenocarcinoma of lung

,

gestational diabetes

,

pregnancy in diabetics

,

coronary disease

,

large b-cell lymphoma diffuse

,

brain neoplasms

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

follicular lymphoma

,

hematopoietic stem cell transplantation

,

peripheral arterial disease

,

atherosclerosis

,

intermittent claudication

,

peripheral vascular diseases

,

,

,

,

,

meningococcal meningitis

,

haemophilus infections

,

cutaneous malignant melanoma

,

esophageal squamous cell carcinoma

,

urinary bladder neoplasms

,

,

rectal neoplasms

,

congenital abnormalities

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

erythroblastic leukemia acute

,

hypersensitivity

,

peanut hypersensitivity

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

allergic rhinitis

,

,

acquired immunodeficiency syndrome

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

pulmonary alveolar proteinosis

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

,

alpha 1-antitrypsin deficiency

,

breast neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

,

,

,

myelodysplastic syndromes

,

,

ovarian neoplasms

,

,

,

graft vs host disease

,

meningococcal infections

,

,

healthy volunteers/patients

,

,

hematologic neoplasms

,

,

pneumococcal pneumonia

,

,

haemophilus influenzae type b

,

,

,

myeloid leukemia

,

,

venous thrombosis

,

rheumatoid arthritis

,

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

thrombotic thrombocytopenic purpura

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

pulmonary embolism

,

,

,

st elevation myocardial infarction

,

glucose intolerance

,

hematologic diseases

,

inborn genetic diseases

,

blood coagulation disorders

,

x-linked genetic diseases

,

hemorrhagic disorders

,

inherited blood coagulation disorders

,

coagulation protein disorders

,

fetal growth retardation

,

thromboembolism

,

noonan syndrome

,

bacterial meningitis

,

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

,

type 2 diabetes mellitus

,

type 1 diabetes mellitus

,

glycogen storage disease type ii

,

,

diabetes mellitus

,

prostatic neoplasms

,

non-hodgkin lymphoma

,

multiple sclerosis

,

,

glycogen storage disease type iii

,

relapsing-remitting multiple sclerosis

,

,

,

graft rejection

,

chronic kidney failure

,

insulin resistance

,

renal insufficiency

,

kidney transplantation

,

autologous transplantation

,

acute coronary syndrome

,

myocardial infarction

,

,

,

liver transplantation

,

psychology rejection

,

atrial fibrillation

,

,

,

,

,

,

,

,

,

inferior wall myocardial infarction

,

kidney diseases

,

coronary artery disease

,

immunosuppression therapy

,

,

,

glycogen storage disease

,

,

lymphoproliferative disorders

,

paraproteinemias

,

heart transplantation

,

reperfusion injury

,

,

,

,

haemophilus infections

,

colorectal neoplasms

,

,

rectal neoplasms

,

squamous cell carcinoma of head and neck

,

chronic obstructive pulmonary disease

,

,

multiple myeloma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

vision disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

neoplasm metastasis

,

,

,

,

myeloid leukemia

,

spondylarthritis

,

,

,

,

psoriatic arthritis

,

ankylosing spondylitis

,

retinal vein occlusion

,

,

chronic urticaria

,

,

cystic fibrosis

,

choroidal neovascularization

,

osteitis deformans

,

renal cell carcinoma

,

philadelphia chromosome

,

ovarian neoplasms

,

pituitary acth hypersecretion

,

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

diabetic retinopathy

,

retinal neovascularization

,

macular degeneration

,

,

hematologic diseases

,

sickle cell anemia

,

sickle cell trait

,

vaso-occlusive crises

,

,

,

,

,

neuroendocrine tumors

,

,

,

gastrointestinal stromal tumors

,

triple negative breast neoplasms

,

myeloid leukemia acute

,

acth-secreting pituitary adenoma

,

,

pseudomonas aeruginosa

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

respiratory aspiration

,

prostatic neoplasms

,

myelomonocytic leukemia chronic

,

,

wet macular degeneration

,

pathologic neovascularization

,

adenocarcinoma of lung

,

brain neoplasms

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

,

lupus nephritis

,

,

axial spondyloarthritis

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

allergic rhinitis seasonal

,

graft vs host disease

,

primary myelofibrosis

,

,

inclusion body myositis

,

juvenile arthritis

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

diabetes mellitus

,

rheumatoid arthritis

,

hereditary sensory and autonomic neuropathies

,

,

hyperlipoproteinemia type i

,

hyperpituitarism

,

degenerative myopia

,

,

non-hodgkin lymphoma

,

,

pulmonary infarction

,

hodgkin disease

,

behcet syndrome

,

,

,

,

giant cell arteritis

,

,

thyroid neoplasms

,

food hypersensitivity

,

peanut hypersensitivity

,

polymyalgia rheumatica

,

male breast neoplasms

,

,

follicular lymphoma

,

polycythemia vera

,

,

,

myeloid leukemia chronic-phase

,

,

iga glomerulonephritis

,

,

left ventricular hypertrophy

,

pathologic dilatation

,

,

essential hypertension

,

systolic murmurs

Pegvorhyaluronidase alfa

esophageal neoplasms

,

pancreatic neoplasms

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