Mephedrone
Mephedrone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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191 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 8 | 8 | 2 | 1 | 1 | 15 |
| Colorectal neoplasms | D015179 | — | — | 8 | 5 | 3 | 1 | 1 | 15 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 1 | 1 | 5 | 1 | 2 | 10 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 3 | 2 | 1 | 2 | 9 |
| Glaucoma | D005901 | EFO_0000516 | H40 | 1 | 1 | 1 | 1 | 4 | 7 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | — | 1 | 3 | 4 |
| Second primary neoplasms | D016609 | — | — | — | — | 1 | 1 | — | 2 |
| Oropharyngeal neoplasms | D009959 | — | — | — | 1 | 1 | 1 | — | 2 |
| Recurrence | D012008 | — | — | — | — | — | 1 | 1 | 2 |
| Cervical intraepithelial neoplasia | — | — | D06 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Urinary bladder neoplasms | D001749 | — | C67 | 6 | 9 | 5 | — | 1 | 19 |
| Carcinoma | D002277 | — | C80.0 | 3 | 5 | 5 | — | 3 | 15 |
| Anus neoplasms | D001005 | EFO_0003835 | C21 | 4 | 9 | 1 | — | 1 | 13 |
| Neoplasms | D009369 | — | C80 | 5 | 2 | 4 | — | 2 | 12 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 3 | 3 | 3 | — | — | 9 |
| Squamous cell carcinoma | D002294 | — | — | 4 | 8 | 1 | — | — | 9 |
| Transitional cell carcinoma | D002295 | — | — | 3 | — | 4 | — | 2 | 9 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 7 | 2 | — | — | 8 |
| Burkitt lymphoma | D002051 | — | C83.7 | — | 7 | 2 | — | — | 8 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 4 | 5 | 2 | — | — | 8 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 2 | 5 | — | — | — | 6 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 1 | — | — | — | 4 |
| Lung neoplasms | D008175 | — | C34.90 | 2 | 3 | — | — | — | 4 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | — | — | — | 3 |
| Multiple myeloma | D009101 | — | C90.0 | — | 3 | — | — | — | 3 |
| Glioma | D005910 | EFO_0000520 | — | — | 3 | — | — | — | 3 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | 2 | — | — | — | 3 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | 1 | — | — | — | 2 |
| Head and neck neoplasms | D006258 | — | — | — | 1 | — | — | 1 | 2 |
| Esophageal neoplasms | D004938 | — | C15 | — | 1 | — | — | 1 | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pterygium | D011625 | — | H11.0 | 1 | — | — | — | 2 | 3 |
| Endometrioid carcinoma | D018269 | — | — | 2 | — | — | — | — | 2 |
| Acinar cell carcinoma | D018267 | — | — | 2 | — | — | — | — | 2 |
| Amphetamine-related disorders | D019969 | EFO_0004701 | F15 | 2 | — | — | — | — | 2 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
| Adult t-cell leukemia-lymphoma | D015459 | — | C91.5 | 1 | — | — | — | — | 1 |
| Deltaretrovirus infections | D006800 | EFO_1001303 | — | 1 | — | — | — | — | 1 |
| Htlv-i infections | D015490 | EFO_0007316 | — | 1 | — | — | — | — | 1 |
| Mucinous cystadenocarcinoma | D018282 | — | — | 1 | — | — | — | — | 1 |
| Mucinous adenocarcinoma | D002288 | — | — | 1 | — | — | — | — | 1 |
Show 14 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 3 | 3 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 2 | 2 |
| Esophageal stenosis | D004940 | — | K22.2 | — | — | — | — | 2 | 2 |
| Pathologic constriction | D003251 | — | — | — | — | — | — | 2 | 2 |
| Postural balance | D004856 | — | — | — | — | — | — | 2 | 2 |
| Pregnancy complications | D011248 | — | — | — | — | — | — | 2 | 2 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | — | — | 1 | 1 |
| Muscle weakness | D018908 | — | — | — | — | — | — | 1 | 1 |
| Deglutition disorders | D003680 | — | R13.1 | — | — | — | — | 1 | 1 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 1 | 1 |
Show 44 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Mephedrone |
| INN | _ |
| Description | Mephedrone, also known as 4-methylmethcathinone, 4-MMC, and 4-methylephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include drone, M-CAT, White Magic, meow meow and bubble. It is chemically similar to the cathinone compounds found in the Khat plant of eastern Africa. It comes in the form of tablets or crystals, which users can swallow, snort or inject, producing effects similar to those of MDMA, amphetamines and cocaine.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CNC(C)C(=O)c1ccc(C)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 1189805-46-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4094396 |
| ChEBI ID | — |
| PubChem CID | 29982893 |
| DrugBank | — |
| UNII ID | G0XL35SUXP (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
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75 adverse events reported
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