Mephedrone
Mephedrone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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164 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 7 | 8 | 2 | 1 | 1 | 14 |
| Colorectal neoplasms | D015179 | — | — | 6 | 5 | 2 | 1 | 1 | 12 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 3 | 2 | 1 | 2 | 9 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 1 | 1 | 4 | 1 | 2 | 9 |
| Glaucoma | D005901 | EFO_0000516 | H40 | 1 | 1 | 1 | 1 | 4 | 7 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | — | 1 | 3 | 4 |
| Oropharyngeal neoplasms | D009959 | — | — | 1 | 1 | 1 | 1 | — | 3 |
| Second primary neoplasms | D016609 | — | — | — | — | 1 | 1 | — | 2 |
| Recurrence | D012008 | — | — | — | — | — | 1 | 1 | 2 |
| Cervical intraepithelial neoplasia | — | — | D06 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 4 | 8 | 7 | — | 3 | 20 |
| Urinary bladder neoplasms | D001749 | — | C67 | 5 | 9 | 3 | — | 1 | 16 |
| Anus neoplasms | D001005 | EFO_0003835 | C21 | 4 | 8 | 1 | — | 1 | 12 |
| Neoplasms | D009369 | — | C80 | 4 | 3 | 3 | — | 1 | 9 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 3 | 3 | 3 | — | — | 9 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | 3 | 2 | — | 2 | 8 |
| Squamous cell carcinoma | D002294 | — | — | 4 | 7 | 1 | — | — | 8 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 6 | 1 | — | — | 7 |
| Transitional cell carcinoma | D002295 | — | — | 2 | — | 3 | — | 2 | 7 |
| Lymphoma | D008223 | — | C85.9 | 2 | 4 | 2 | — | — | 6 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 2 | 5 | — | — | — | 6 |
| Burkitt lymphoma | D002051 | — | C83.7 | — | 5 | — | — | — | 5 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 1 | — | — | — | 4 |
| Lung neoplasms | D008175 | — | C34.90 | 2 | 3 | — | — | — | 4 |
| B-cell lymphoma | D016393 | — | — | 2 | 3 | — | — | — | 4 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | — | — | — | 3 |
| Multiple myeloma | D009101 | — | C90.0 | — | 3 | — | — | — | 3 |
| Glioma | D005910 | EFO_0000520 | — | — | 3 | — | — | — | 3 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | 1 | — | — | — | 2 |
| Head and neck neoplasms | D006258 | — | — | — | 1 | — | — | 1 | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pterygium | D011625 | — | H11.0 | 1 | — | — | — | 2 | 3 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 2 | — | — | — | — | 2 |
| Appendiceal neoplasms | D001063 | EFO_0003880 | C18.1 | 2 | — | — | — | — | 2 |
| Endometrioid carcinoma | D018269 | — | — | 2 | — | — | — | — | 2 |
| Acinar cell carcinoma | D018267 | — | — | 2 | — | — | — | — | 2 |
| Amphetamine-related disorders | D019969 | EFO_0004701 | F15 | 2 | — | — | — | — | 2 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
| Adult t-cell leukemia-lymphoma | D015459 | — | C91.5 | 1 | — | — | — | — | 1 |
| Deltaretrovirus infections | D006800 | EFO_1001303 | — | 1 | — | — | — | — | 1 |
| Htlv-i infections | D015490 | EFO_0007316 | — | 1 | — | — | — | — | 1 |
Show 16 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 2 | 2 |
| Esophageal stenosis | D004940 | — | K22.2 | — | — | — | — | 2 | 2 |
| Pathologic constriction | D003251 | — | — | — | — | — | — | 2 | 2 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | — | — | 1 | 1 |
| Muscle weakness | D018908 | — | — | — | — | — | — | 1 | 1 |
| Deglutition disorders | D003680 | — | R13.1 | — | — | — | — | 1 | 1 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 1 | 1 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 1 | 1 |
| Gastroparesis | D018589 | EFO_1000948 | K31.84 | — | — | — | — | 1 | 1 |
| Traumatic brain injuries | D000070642 | — | S06 | — | — | — | — | 1 | 1 |
Show 29 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Mephedrone |
| INN | _ |
| Description | Mephedrone, also known as 4-methylmethcathinone, 4-MMC, and 4-methylephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include drone, M-CAT, White Magic, meow meow and bubble. It is chemically similar to the cathinone compounds found in the Khat plant of eastern Africa. It comes in the form of tablets or crystals, which users can swallow, snort or inject, producing effects similar to those of MDMA, amphetamines and cocaine.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CNC(C)C(=O)c1ccc(C)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 1189805-46-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4094396 |
| ChEBI ID | — |
| PubChem CID | 29982893 |
| DrugBank | — |
| UNII ID | G0XL35SUXP (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
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67 adverse events reported
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