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CorMedix(CRMD)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Defencath	Heparin, Taurolidine	2023-11-15	2024-2042	Myocardial infarction , Pulmonary embolism , Postoperative complications , Thromboembolism , Cerebral infarction , Coronary thrombosis , Unstable angina , Thrombophlebitis , Migraine disorders , Pain , Ventricular tachycardia , Orthostatic hypotension , Cardiac arrhythmias , Cluster headache , Postpartum hemorrhage , Xerostomia , Burns , Esophageal diseases , Ventricular fibrillation , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

thromboembolism

,

,

venous thromboembolism

,

venous thrombosis

,

pulmonary embolism

,

gastrointestinal neoplasms

,

thrombocytopenia

chronic kidney failure

,

renal insufficiency

,

,

,

communicable diseases

,

catheter-related infections

blood platelet disorders

,

,

intracranial hypertension

,

non-hodgkin lymphoma

,

hodgkin disease

,

congenital abnormalities

,

systemic lupus erythematosus

,

,

sensorineural hearing loss

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

cesarean section

,

,

,

eosinophilic esophagitis

,

,

,

,

falciparum malaria

,

,

,

protein-losing enteropathies

,

intestinal diseases

,

univentricular heart

,

clear cell sarcoma

,

,

choroid plexus neoplasms

,

choroid plexus papilloma

,

t-cell lymphoma

,

sinus floor augmentation

,

,

sudden hearing loss

,

,

cholangiocarcinoma

,

coronary stenosis

,

ovarian neoplasms

,

congenital heart defects

,

carotid artery diseases

,

myeloid leukemia

,

renal cell carcinoma

,

systemic inflammatory response syndrome

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

kidney neoplasms

,

,

ovarian epithelial carcinoma

,

,

embolism and thrombosis

,

cardiogenic shock

,

,

acute-on-chronic liver failure

,

spinal cord injuries

,

biliary tract neoplasms

,

vascular access devices

,

,

patent foramen ovale

,

staphylococcal infections

,

,

catheter obstruction

,

,

urinary tract infections

,

,

arteriosclerosis

,

urinary bladder diseases

,

,

renal replacement therapy

,

hepatic insufficiency

,

intestinal failure

,

duodenal neoplasms

,

gastrointestinal stromal tumors

,

gallbladder neoplasms

,

ampulla of vater cancer

,

somatoform disorders

,

,

plastic surgery procedures

,

,

staphylococcus aureus

,

radiation injuries

,

central venous catheters

,

addictive behavior

,

,

,

,

lower urinary tract symptoms

,

,

,

neurobehavioral manifestations

,

hypertrophic pyloric stenosis

,

,

,

short bowel syndrome

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

vascular graft occlusion

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

bile duct neoplasms

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

adrenal gland neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

end stage liver disease

,

hemolytic anemia autoimmune

,

thrombocytopenic purpura idiopathic

,

protein s deficiency

,

,

,

schizophrenia spectrum and other psychotic disorders

,

,

marijuana abuse

,

healthy volunteers/patients

,

,

cardiovascular diseases

,

multiple myeloma

,

,

replacement arthroplasty knee

,

newborn respiratory distress syndrome

,

,

plasma cell neoplasms

,

coagulation protein disorders

,

,

,

premature birth

,

,

intracranial aneurysm

,

heart valve diseases

,

stomach neoplasms

,

myeloid leukemia acute

,

,

,

extracorporeal membrane oxygenation

,

aortic dissection

,

brain neoplasms

,

female genital neoplasms

,

,

chronic limb-threatening ischemia

,

proliferative vitreoretinopathy

,

neoplasm metastasis

,

nephrotic syndrome

,

intracranial hemorrhages

,

non-small-cell lung carcinoma

,

postoperative hemorrhage

,

,

,

,

,

postpartum period

,

,

pseudotumor cerebri

,

colonic neoplasms

,

,

transcatheter aortic valve replacement

,

subarachnoid hemorrhage

,

myeloproliferative disorders

,

sickle cell anemia

,

,

,

cardiac catheterization

,

,

hepatic veno-occlusive disease

,

,

respiratory tract infections

,

respiratory tract diseases

,

community-acquired pneumonia

,

retinal vein occlusion

,

myelodysplastic syndromes

,

,

migraine disorders

,

,

vertebral artery dissection

,

,

hemorrhagic stroke

,

small cell lung carcinoma

,

rectal neoplasms

,

,

disseminated intravascular coagulation

,

dental occlusion

,

retinal detachment

,

dissociative disorders

,

cardiomyopathies

,

acute chest syndrome

,

cardiac arrhythmias

,

hematologic neoplasms

,

intraabdominal infections

,

uterine cervical neoplasms

,

,

human influenza

,

budd-chiari syndrome

,

splenic infarction

,

,

retinal artery occlusion

,

,

,

,

internal carotid artery dissection

,

abdominal neoplasms

,

,

pharmacological phenomena

,

peripartum cardiomyopathy

,

vascular patency

,

endovascular procedures

,

,

respiratory aspiration

,

metabolic diseases

,

aplastic anemia

,

metabolic brain diseases

,

intra-abdominal hypertension

,

compartment syndromes

,

,

digestive system diseases

,

diabetic angiopathies

,

,

breast neoplasms

,

may-thurner syndrome

,

gram-negative bacterial infections

,

precancerous conditions

,

,

,

ventricular dysfunction

,

headache disorders

,

,

bacterial pneumonia

,

cavernous sinus thrombosis

,

smoke inhalation injury

,

idiopathic pulmonary fibrosis

,

,

thromboembolism

,

venous thromboembolism

,

venous thrombosis

,

,

pulmonary embolism

,

,

myocardial infarction

,

,

,

,

coronary artery disease

,

thrombocytopenia

,

acute coronary syndrome

,

,

atrial fibrillation

,

,

,

chronic kidney failure

,

renal insufficiency

,

acute kidney injury

,

st elevation myocardial infarction

,

catheter-related infections

,

cardiac surgical procedures

,

myocardial ischemia

,

,

coronary disease

,

hemostatic disorders

,

critical illness

,

,

respiratory distress syndrome

,

communicable diseases

,

liver cirrhosis

,

,

diabetes mellitus

,

,

inferior wall myocardial infarction

,

,

,

colorectal neoplasms

,

blood coagulation disorders

,

wounds and injuries

,

,

chronic renal insufficiency

,

respiratory insufficiency

,

,

pancreatic neoplasms

,

atherosclerosis

,

unstable angina

,

ischemic stroke

,

,

cardiopulmonary bypass

,

arterial occlusive diseases

,

antiphospholipid syndrome

,

percutaneous coronary intervention

,

habitual abortion

,

interstitial cystitis

,

,

spontaneous abortion

,

acute lung injury

,

kidney diseases

,

,

,

peripheral arterial disease

,

,

,

,

type 2 diabetes mellitus

,

coronary artery bypass

,

,

,

type 1 diabetes mellitus

,

,

,

peripheral vascular diseases

,

coronavirus infections

,

liver neoplasms

,

intracranial thrombosis

,

postthrombotic syndrome

,

angina pectoris

,

,

,

,

insulin resistance

,

fetal growth retardation

,

,

aortic valve stenosis

,

vascular diseases

,

pregnancy complications

,

severe acute respiratory syndrome

,

non-st elevated myocardial infarction

,

,

,

cerebral infarction

,

bacterial infections

,

hypersensitivity

,

portal hypertension

,

hepatocellular carcinoma

,

esophageal neoplasms

,

upper extremity deep vein thrombosis

,

postphlebitic syndrome

,

viral pneumonia

,

,

balloon angioplasty coronary

,

traumatic brain injuries

,

,

replacement arthroplasty hip

,

,

,

thrombophlebitis

,

surgical blood loss

,

lung transplantation

,

right ventricular dysfunction

,

high-risk pregnancy

,

,

,

female infertility

,

injection site reaction

,

knee osteoarthritis

,

,

intracranial sinus thrombosis

,

aortic aneurysm

,

extracorporeal circulation

,

prostatic neoplasms

,

hypercholesterolemia

,

mesenteric ischemia

,

,

gastrointestinal hemorrhage

,

artificial respiration

,

pulmonary hypertension

,

severe acute respiratory syndrome-related coronavirus

,

gastrointestinal neoplasms

,

hip osteoarthritis

,

,

cerebral hemorrhage

,

multiple organ failure

,

,

blood transfusion

,

coronary angiography

,

arteriovenous fistula

,

,

metabolic syndrome

,

,

placental insufficiency

,

,

mitral valve insufficiency

,

digestive system neoplasms

,

,

abdominal aortic aneurysm

,

,

,

intracranial vasospasm

,

thoracic surgical procedures

,

catheter ablation

,

,

,

continuous renal replacement therapy

,

hyperlipoproteinemia type ii

,

,

antithrombin iii deficiency

,

,

,

hematologic diseases

,

intermittent claudication

,

hemodiafiltration

,

,

diabetes complications

,

,

pulmonary infarction

,

,

drug interactions

,

femoral neck fractures

,

femur head necrosis

,

graft rejection

,

mechanical ventilators

,

,

,

cardiovascular surgical procedures

,

extravasation of diagnostic and therapeutic materials

,

exfoliation syndrome

,

,

medical sociology

,

,

blood component removal

,

severe fever with thrombocytopenia syndrome

,

,

antibiotic prophylaxis

,

cerebral angiography

,

,

,

major depressive disorder

,

head and neck neoplasms

,

,

autoimmune diseases

,

pregnancy-induced hypertension

,

postoperative complications

,

carotid stenosis

,

,

pathologic constriction

,

non-alcoholic fatty liver disease

,

,

post-acute covid-19 syndrome

,

cytokine release syndrome

,

blood coagulation

,

esophageal and gastric varices

,

platelet aggregation

,

ventilator-associated pneumonia

,

bariatric surgery

,

,

,

connective tissue diseases

,

venous insufficiency

,

traumatic intracranial hemorrhage

,

fertilization in vitro

,

assisted reproductive techniques

,

,

endoscopic ultrasound-guided fine needle aspiration

,

,

,

hyperlipoproteinemia type i

,

,

liver transplantation

,

thoracic aortic aneurysm

,

autoimmune diseases of the nervous system

,

drug-related side effects and adverse reactions

,

prostatic hyperplasia

,

blood coagulation tests

,

,

latent tuberculosis

,

renal artery obstruction

,

female genital diseases

,

,

,

platelet activation

,

,

tissue adhesions

,

,

,

,

,

,

,

,

renin-angiotensin system

,

craniocerebral trauma

,

scimitar syndrome

,

optical coherence tomography

,

,

,

patient reported outcome measures

,

undifferentiated connective tissue diseases

,

erectile dysfunction

,

,

transient ischemic attack

,

soft tissue neoplasms

,

,

,

epidural analgesia

,

carotid artery injuries

,

polycystic ovary syndrome

,

eye abnormalities

,

,

heart valve prosthesis

,

,

atrial heart septal defects

,

heart septal defects

,

abruptio placentae

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

,

cardiac valve annuloplasty

,

,

atopic dermatitis

,

prospective studies

,

,

allergic rhinitis seasonal

,

venom hypersensitivity

,

dust mite allergy

,

perioperative period

,

,

,

alcoholic fatty liver

,

,

,

,

tibial fractures

,

,

respiration disorders

,

neurodegenerative diseases

,

,

arteriovenous malformations

,

,

environmental biomarkers

,

disease progression

,

heart-assist devices

,

mycobacterium tuberculosis

,

popliteal artery aneurysm

,

blood specimen collection

,

,

dysgammaglobulinemia

,

hyperlipidemias

,

hyperlipoproteinemias

,

primary ovarian insufficiency

,

premature menopause

,

orthopedic procedures

,

,

,

hyperinsulinism

,

diagnostic techniques and procedures

,

,

multiple acyl coenzyme a dehydrogenase deficiency

,

renovascular hypertension

,

homozygous familial hypercholesterolemia

,

cytoreduction surgical procedures

,

,

,

epidermolysis bullosa

,

epidermolysis bullosa dystrophica

,

macular degeneration

,

collateral circulation

,

,

urogenital neoplasms

,

genital diseases

,

spinal stenosis

,

arteriosclerosis obliterans

,

heart disease risk factors

,

,

off-pump coronary artery bypass

,

intermittent pneumatic compression devices

,

thrombelastography

,

,

coronary restenosis

,

,

femoral fractures

,

spontaneous fractures

,

hyperandrogenism

,

glomerular filtration rate

,

renal circulation

,

renal plasma flow

,

peritoneal dialysis

,

food diet and nutrition

,

,

,

myocardial bridging

,

microvascular angina

,

central nervous system infections

,

lymphoproliferative disorders

,

hospitalization

,

aortic diseases

,

anhidrotic ectodermal dysplasia 1

,

,

,

enhanced recovery after surgery

,

preoperative exercise

,

,

kidney transplantation

,

,

inguinal hernia

,

,

cholecystectomy

,

diabetic nephropathies

,

chronic disease

,

acute liver failure

,

,

,

mediastinal emphysema

,

,

loeys-dietz syndrome

,

immunosuppression therapy

,

cognition disorders

,

neurocognitive disorders

,

acupuncture therapy

,

ultrasonic therapy

,

,

,

pancreaticoduodenectomy

,

subcutaneous injections

,

,

arrhythmogenic right ventricular dysplasia

,

camurati-engelmann syndrome

,

electronic health records

,

premature rupture fetal membranes

,

chorioamnionitis

,

,

,

,

lymphatic diseases

,

anastomotic leak

,

,

ultrasonography

,

,

,

urinary bladder neoplasms

,

capillary fragility

,

,

hereditary autoinflammatory diseases

,

pericardial effusion

,

endometrial neoplasms

,

vaginal neoplasms

,

pleural effusion

,

prediabetic state

,

pancreatic ductal carcinoma

,

patient satisfaction

,

antibody specificity

,

collagen diseases

,

psychogenic polydipsia

,

diabetes insipidus

,

neurogenic diabetes insipidus

,

nephrogenic diabetes insipidus

,

,

,

,

pulmonary tuberculosis

,

extrapulmonary tuberculosis

,

hypoalbuminemia

,

,

,

anxiety disorders

,

,

postoperative pain

,

hypertrophic cicatrix

,

thrombolytic therapy

,

pulmonary edema

,

dual anti-platelet therapy

,

premature obstetric labor

,

postpartum depression

,

uterine cervical incompetence

,

pregnancy outcome

,

,

,

,

retinal diseases

,

kidney diseases

,

chronic renal insufficiency

,

type 2 diabetes mellitus

,

diabetes mellitus

,

chronic kidney failure

,

,

renal insufficiency

,

,

chronic hepatitis c

,

,

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

rectal neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

stomach neoplasms

,

,

,

ovarian neoplasms

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

hepatocellular carcinoma

,

liver neoplasms

,

,

b-cell lymphoma

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

,

,

lupus nephritis

,

ductal carcinoma breast

,

macular degeneration

,

,

renal cell carcinoma

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

urinary bladder neoplasms

,

colonic neoplasms

,

,

head and neck neoplasms

,

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

pancreatic neoplasms

,

,

,

,

neoplasms by site

,

breast diseases

,

urologic neoplasms

,

prostatic neoplasms

,

,

follicular lymphoma

,

lymphoid leukemia

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

atypical hemolytic uremic syndrome

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

ovarian epithelial carcinoma

,

brain neoplasms

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

vision disorders

,

,

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

,

endometrioid carcinoma

,

giant cell arteritis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

membranous glomerulonephritis

,

multiple sclerosis

,

chronic progressive multiple sclerosis

,

ankylosing spondylitis

,

spondylarthritis

,

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

bcr-abl positive chronic myelogenous leukemia

,

circulating neoplastic cells

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

,

hemolytic anemia autoimmune

,

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

endometrial neoplasms

,

,

graft rejection

,

retinal neovascularization

,

human influenza

,

type 3 von willebrand disease

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

chronic kidney failure

,

renal insufficiency

,

,

,

communicable diseases

,

catheter-related infections

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