Zimberelimab
Zimberelimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
67 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 6 | 7 | 1 | — | — | 13 |
| Uterine cervical neoplasms | D002583 | HP_0030159 | — | 2 | 7 | 1 | — | — | 10 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 2 | 6 | 1 | — | — | 8 |
| Adenocarcinoma | D000230 | — | — | 2 | 4 | 1 | — | — | 5 |
| Lymphoma | D008223 | — | C85.9 | 1 | 2 | 1 | — | — | 4 |
| Hodgkin disease | D006689 | — | C81 | — | 2 | 1 | — | — | 3 |
| Recurrence | D012008 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 14 | 4 | — | — | — | 16 |
| Carcinoma | D002277 | — | C80.0 | 5 | 7 | — | — | — | 10 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 3 | 4 | — | — | 1 | 6 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | 2 | — | — | — | 5 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 4 | 1 | — | — | — | 5 |
| Urinary bladder neoplasms | D001749 | — | C67 | 2 | 2 | — | — | — | 4 |
| Squamous cell carcinoma | D002294 | — | — | 2 | 3 | — | — | — | 4 |
| Esophageal neoplasms | D004938 | — | C15 | 3 | 1 | — | — | — | 4 |
| Colorectal neoplasms | D015179 | — | — | 3 | 1 | — | — | — | 3 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 3 | — | — | — | 3 |
Show 23 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | — | — | — | — | 2 |
| Head and neck neoplasms | D006258 | — | — | 2 | — | — | — | — | 2 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | — | — | — | — | 1 |
| Merkel cell carcinoma | D015266 | EFO_1001471 | C4A | 1 | — | — | — | — | 1 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
| Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | — | — | — | — | 1 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Mouth neoplasms | D009062 | EFO_0003868 | C06.9 | 1 | — | — | — | — | 1 |
| Oropharyngeal neoplasms | D009959 | — | — | 1 | — | — | — | — | 1 |
Show 5 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Radiosurgery | D016634 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Zimberelimab |
| INN | zimberelimab |
| Description | Zimberelimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297856 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | ZBL7O904IL (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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133 adverse events reported
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