Cirmtuzumab
Cirmtuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 3 | 6 | 2 | — | — | 8 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 2 | 4 | 1 | — | — | 5 |
| Mantle-cell lymphoma | D020522 | — | — | 2 | 2 | 1 | — | — | 4 |
| B-cell lymphoma | D016393 | — | — | — | 2 | 2 | — | — | 3 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | 1 | — | — | 2 |
| Immune system diseases | D007154 | — | D89.9 | — | — | 1 | — | — | 1 |
| Lymphoproliferative disorders | D008232 | Orphanet_2442 | D47.9 | — | — | 1 | — | — | 1 |
| Lymphatic diseases | D008206 | HP_0100763 | — | — | — | 1 | — | — | 1 |
| Immunoproliferative disorders | D007160 | — | C88.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 4 | 3 | — | — | — | 6 |
| Lymphoid leukemia | D007945 | — | C91 | 4 | 2 | — | — | — | 5 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 1 | — | — | — | 2 |
| B-cell lymphoma marginal zone | D018442 | — | C88.4 | 2 | 1 | — | — | — | 2 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | 2 | 1 | — | — | — | 2 |
| Follicular lymphoma | D008224 | — | C82 | 1 | 1 | — | — | — | 2 |
| Burkitt lymphoma | D002051 | — | C83.7 | 2 | 1 | — | — | — | 2 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | — | 1 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | 1 | — | — | — | 1 |
| Triple negative breast neoplasms | D064726 | — | — | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 3 | — | — | — | — | 3 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
| T-cell lymphoma | D016399 | — | — | 1 | — | — | — | — | 1 |
| Waldenstrom macroglobulinemia | D008258 | HP_0005508 | C88.0 | 1 | — | — | — | — | 1 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | — | 1 |
| Castration-resistant prostatic neoplasms | D064129 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cirmtuzumab |
| INN | zilovertamab |
| Description | Cirmtuzumab (also UC-961) is an anti-ROR1 humanised monoclonal antibody.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297728 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | FEH7RQ7B3J (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
Black-box Warning
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Adverse Events
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