PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsZidovudine
Retrovir, Combivir(zidovudine)
/ Lamivudine / Zidovudine, Combivir, Lamivudine / Zidovudine, Retrovir, Trizivir, Zidovudine (zidovudine) is a small molecule pharmaceutical. Zidovudine was first approved as Retrovir on 1987-03-19. It is used to treat acquired immunodeficiency syndrome and HIV infections in the USA. It has been approved in Europe to treat HIV infections.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
urogenital diseasesD000091642
immune system diseasesD007154
Trade Name
FDA
EMA
Retrovir, Zidovudine (discontinued: Retrovir, Zidovudine)
Combinations
Abacavir sulfate, lamivudine zidovudine, Lamivudine zidovudine (discontinued: Combivir, Lamivudine zidovudine, Lamivudine, nevirapine zidovudine, Trizivir)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Zidovudine
Tradename
Company
Number
Date
Products
RETROVIRViiV HealthcareN-019655 RX1987-03-19
1 products, RLD, RS
RETROVIRViiV HealthcareN-019910 RX1989-09-28
1 products, RLD, RS
RETROVIRViiV HealthcareN-019951 RX1990-02-02
1 products, RLD, RS
Show 3 discontinued
Lamivudine
+
Nevirapine
+
Zidovudine
Tradename
Company
Number
Date
Products
LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINEMicro LaboratoriesN-205626 DISCN2018-08-13
1 products, RLD
Hide discontinued
Lamivudine
+
Zidovudine
Tradename
Company
Number
Date
Products
LAMIVUDINE AND ZIDOVUDINEPharmaCareN-022018 DISCN2017-03-17
1 products
COMBIVIRViiV HealthcareN-020857 DISCN1997-09-26
1 products, RLD
Hide discontinued
Abacavir sulfate
+
Lamivudine
+
Zidovudine
Tradename
Company
Number
Date
Products
TRIZIVIRViiV HealthcareN-021205 DISCN2000-11-14
1 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
abacavir sulfate, lamivudine and zidovudineANDA2013-12-17
abacavir, lamivudine and zidovudineANDA2023-10-31
azactamNew Drug Application2025-01-09
aztreonamANDA2024-06-03
caystonNew Drug Application2025-03-17
combivirNew Drug Application2023-08-22
compound wC2002632025-08-08
compound w for kids one step stripsC2002632024-10-25
compound w one step padsC2002632024-10-25
compound w one step plantar foot padsC2002632024-10-25
Show 15 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
hiv infectionsEFO_0000764D015658B20
acquired immunodeficiency syndromeEFO_0000765D000163B20
hepatitis b—D006509—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J05: Antivirals for systemic use
— J05A: Direct acting antivirals
— J05AF: Nucleoside and nucleotide reverse transcriptase inhibitors
— J05AF01: Zidovudine
— J05AR: Antivirals for treatment of hiv infections, combinations
— J05AR01: Zidovudine and lamivudine
— J05AR04: Zidovudine, lamivudine and abacavir
— J05AR05: Zidovudine, lamivudine and nevirapine
HCPCS
Code
Description
J3485
Injection, zidovudine, 10 mg
S0104
Zidovudine, oral, 100 mg
Clinical
Clinical Trials
597 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B20—1—135
Acquired immunodeficiency syndromeD000163EFO_0000765B20—1—135
HivD006678—O98.7———2—2
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv-1D015497————1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_0000544——1——34
Communicable diseasesD003141———1——12
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Immunologic deficiency syndromesD007153—D84.9————22
Bone fracturesD050723EFO_0003931T14.8————11
Cardiovascular diseasesD002318EFO_0000319I98————11
Myocardial infarctionD009203EFO_0000612I21————11
InfarctionD007238EFO_0009463—————11
Inferior wall myocardial infarctionD056989EFO_1000983—————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameZidovudine
INNzidovudine
Description
Zidovudine is a pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. It has a role as an antiviral drug, an antimetabolite and a HIV-1 reverse transcriptase inhibitor. It is a pyrimidine 2',3'-dideoxyribonucleoside and an azide.
Classification
Small molecule
Drug classantineoplastics; antivirals (zidovudine group) (exception: edoxudine)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O
Identifiers
PDB—
CAS-ID30516-87-1
RxCUI—
ChEMBL IDCHEMBL129
ChEBI ID10110
PubChem CID35370
DrugBankDB00495
UNII ID4B9XT59T7S (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Azactam – Elan Corporation
Plot placeholder
Mock data
Subscribe for the real data
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Estimated US medical usage
Zidovudine
+
Lamivudine
+
Abacavir
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Zidovudine
+
Lamivudine
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Zidovudine
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 1,435,441 documents
View more details
Safety
Black-box Warning
Black-box warning for: Abacavir sulfate, lamivudine and zidovudine, Abacavir, lamivudine and zidovudine, Combivir, Direct rx, Lamivudine and zidovudine, Lamivudine zidovudine, Retrovir, Trizivir, Zidovudine
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
30,930 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use