Zatolmilast
Zatolmilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
No data
Clinical
Clinical Trials
14 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fragile x syndrome | D005600 | — | Q99.2 | — | 2 | 3 | — | — | 4 |
| Syndrome | D013577 | — | — | — | 3 | 2 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 3 | 1 | — | — | — | 4 |
| Depression | D003863 | — | F33.9 | 1 | 1 | — | — | — | 1 |
| Neurodevelopmental disorders | D065886 | — | F89 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dementia | D003704 | EFO_0003862 | F03 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
| Hepatic insufficiency | D048550 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Zatolmilast |
| INN | zatolmilast |
| Description | Zatolmilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | antiasthmatics/antiallergics (not acting primarily as antihistamines): type IV phosphodiesterase |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)Cc1ccc(Cc2cc(-c3cccc(Cl)c3)nc(C(F)(F)F)c2)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 1606974-33-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4541964 |
| ChEBI ID | — |
| PubChem CID | 90111638 |
| DrugBank | DB14790 |
| UNII ID | G786V328X6 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Additional graphs summarizing 135 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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