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Drug ReportsZIMLOVISERTIB
ZIMLOVISERTIB
Zimlovisertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-1 receptor-associated kinase 4.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.922
ArthritisD001168HP_0001369M05-M1422
Covid-19D00008638222
Hidradenitis suppurativaD017497L73.211
HidradenitisD01657511
PneumoniaD011014EFO_000310611
InflammationD007249MP_000184511
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients77
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameZIMLOVISERTIB
INNzimlovisertib
Description
Zimlovisertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-1 receptor-associated kinase 4.
Classification
Small molecule
Drug classserine/threonine kinase inhibitors
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Structure (InChI/SMILES or Protein Sequence)
CC[C@H]1[C@@H](COc2nccc3cc(C(N)=O)c(OC)cc23)NC(=O)[C@H]1F
Identifiers
PDB
CAS-ID1817626-54-2
RxCUI
ChEMBL IDCHEMBL4081711
ChEBI ID
PubChem CID118414016
DrugBankDB15143
UNII IDS3F315JJXI (ChemIDplus, GSRS)
Target
Agency Approved
IRAK4
IRAK4
Organism
Homo sapiens
Gene name
IRAK4
Gene synonyms
NCBI Gene ID
Protein name
interleukin-1 receptor-associated kinase 4
Protein synonyms
Renal carcinoma antigen NY-REN-64
Uniprot ID
Mouse ortholog
Irak4 (266632)
interleukin-1 receptor-associated kinase 4 (Q8R4K2)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 166 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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