Vorolanib
Vorolanib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
23 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 1 | 2 | 1 | — | 2 | 5 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | — | C34.90 | 1 | 6 | — | — | — | 6 |
| Small cell lung carcinoma | D055752 | — | — | 1 | 4 | — | — | — | 4 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 3 | — | — | — | 3 |
| Carcinoma | D002277 | — | C80.0 | — | 1 | — | — | 2 | 3 |
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 1 | 1 | — | — | 2 | 3 |
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | 1 | — | — | — | 2 |
| Thoracic neoplasms | D013899 | — | — | 1 | 1 | — | — | — | 1 |
| Thymoma | D013945 | — | — | 1 | 1 | — | — | — | 1 |
| Thymus neoplasms | D013953 | — | C37 | 1 | 1 | — | — | — | 1 |
| Melanoma | D008545 | — | — | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 6 | — | — | — | 1 | 7 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | — | — | — | — | 1 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 1 | — | — | — | — | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | — | — | — | — | 1 |
| Adenocarcinoma | D000230 | — | — | 1 | — | — | — | — | 1 |
| Choroidal neovascularization | D020256 | — | — | 1 | — | — | — | — | 1 |
| Myopia | D009216 | EFO_0003927 | H52.1 | 1 | — | — | — | — | 1 |
| Pathologic neovascularization | D009389 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | — | 1 | 1 |
| Urologic neoplasms | D014571 | — | C64-C68 | — | — | — | — | 1 | 1 |
| Urogenital neoplasms | D014565 | EFO_0003863 | D07 | — | — | — | — | 1 | 1 |
| Urologic diseases | D014570 | — | N39.9 | — | — | — | — | 1 | 1 |
| Male urogenital diseases | D052801 | — | — | — | — | — | — | 1 | 1 |
| Female urogenital diseases | D052776 | — | — | — | — | — | — | 1 | 1 |
| Urogenital diseases | D000091642 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Vorolanib |
| INN | vorolanib |
| Description | Vorolanib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | angiogenesis inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)N[C@H]1CCN(C(=O)N(C)C)C1 |
Identifiers
| PDB | — |
| CAS-ID | 1013920-15-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297587 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | YP8G3I74EL (ChemIDplus, GSRS) |
Target
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Variants
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Trends
PubMed Central
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Additional graphs summarizing 112 documents
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Safety
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Adverse Events
Top Adverse Reactions
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14 adverse events reported
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