Vonapanitase
Vonapanitase is an enzyme pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
41 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatitis | D010195 | EFO_0000278 | K85 | — | — | — | 1 | 6 | 7 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | 1 | 3 | 4 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic renal insufficiency | D051436 | — | N18 | 2 | 3 | 2 | — | — | 5 |
| Arteriovenous fistula | D001164 | — | Q27.3 | 1 | 2 | 2 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Exocrine pancreatic insufficiency | D010188 | — | K86.81 | — | 1 | — | — | 9 | 10 |
| Chronic pancreatitis | D050500 | EFO_0000342 | K86.1 | — | 1 | — | — | 4 | 5 |
| Acute lung injury | D055371 | EFO_0004610 | — | 1 | 1 | — | — | 1 | 3 |
| Fibrosis | D005355 | — | — | — | 2 | — | — | 1 | 3 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | 1 | 2 |
| Respiratory tract diseases | D012140 | — | — | — | 1 | — | — | 1 | 2 |
| Respiration disorders | D012120 | — | J00-J99 | — | 1 | — | — | 1 | 2 |
| Graft vs host disease | D006086 | — | D89.81 | 2 | 2 | — | — | — | 2 |
| Bronchiectasis | D001987 | — | J47 | — | 1 | — | — | 1 | 2 |
| Fistula | D005402 | — | — | 1 | 2 | — | — | — | 2 |
Show 14 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peripheral arterial disease | D058729 | EFO_0004265 | — | 3 | — | — | — | — | 3 |
| Pathologic constriction | D003251 | — | — | 2 | — | — | — | — | 2 |
| Chronic limb-threatening ischemia | D000089802 | — | — | 1 | — | — | — | — | 1 |
| Intermittent claudication | D007383 | EFO_0003876 | I73.9 | 1 | — | — | — | — | 1 |
| Lung injury | D055370 | — | S27.30 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 3 | 3 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | — | — | — | 2 | 2 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | — | — | 2 | 2 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | — | — | — | 2 | 2 |
| Body weight | D001835 | EFO_0004338 | — | — | — | — | — | 1 | 1 |
| Weight gain | D015430 | — | — | — | — | — | — | 1 | 1 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Respiratory insufficiency | D012131 | — | J96.9 | — | — | — | — | 1 | 1 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Vonapanitase |
| INN | vonapanitase |
| Description | Vonapanitase is an enzyme pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Enzyme |
| Drug class | enzymes |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545070 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 3LWJ2H14I9 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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