Vindesine
Vindesine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
81 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | — | 1 | 1 | — | — | 2 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | — | — | 1 | — | — | 1 |
| B-cell lymphoma | D016393 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Central nervous system neoplasms | D016543 | — | — | — | 1 | — | — | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Vindesine |
| INN | vindesine |
| Description | Vindesine is a vinca alkaloid, a methyl ester, an organic heterotetracyclic compound, an organic heteropentacyclic compound, a tertiary alcohol, a tertiary amino compound and a primary carboxamide. It has a role as an antineoplastic agent. It is functionally related to a vincaleukoblastine. |
| Classification | Small molecule |
| Drug class | vinca alkaloids |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@]1(O)C[C@@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C)[C@H]3[C@@](O)(C(N)=O)[C@H](O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1 |
Identifiers
| PDB | — |
| CAS-ID | 53643-48-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL238071 |
| ChEBI ID | — |
| PubChem CID | 40839 |
| DrugBank | DB00309 |
| UNII ID | RSA8KO39WH (ChemIDplus, GSRS) |
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Safety
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2,209 adverse events reported
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