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Drug ReportsVidarabine
Vidarabine
Vira-a (vidarabine) is a small molecule pharmaceutical. Vidarabine was first approved as Vira-a on 1982-01-01. It is used to treat chickenpox, herpes simplex, herpes zoster, herpetic keratitis, and infectious keratoconjunctivitis in the USA. The pharmaceutical is active against adenosine deaminase.
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Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
eye diseasesD005128
skin and connective tissue diseasesD017437
animal diseasesD000820
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Vidarabine
Tradename
Company
Number
Date
Products
VIRA-AParkedale PharmaceuticalsN-050486 DISCN1982-01-01
1 products
VIRA-AParkedale PharmaceuticalsN-050523 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J05: Antivirals for systemic use
— J05A: Direct acting antivirals
— J05AB: Nucleosides and nucleotides excl. reverse transcriptase inhibitors
— J05AB03: Vidarabine
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AD: Antivirals, ophthalmologic
— S01AD06: Vidarabine
HCPCS
No data
Clinical
Clinical Trials
5913 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HepatitisD006505—K75.912921712493190708
Hiv infectionsD015658EFO_0000764B201631459758162601
Hepatitis aD006506EFO_0007305B1510318610085152587
Human influenzaD007251EFO_0007328J11.114218112370101576
Hepatitis cD006526—B19.29917812865138571
InfectionsD007239EFO_0000544—1241568622168515
Covid-19D000086382—U07.1621097931188431
Virus diseasesD014777—B341261246013100397
Hepatitis bD006509——66110644293351
Myeloid leukemia acuteD015470—C92.014418043314327
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Precursor cell lymphoblastic leukemia-lymphomaD054198—C91.0639429—11175
Myelodysplastic syndromesD009190—D466410110—9154
RecurrenceD012008——52598—11109
DengueD003715—A90452811—1496
Lymphoid leukemiaD007945—C91324210—274
Hodgkin diseaseD006689—C8126426—1071
PreleukemiaD011289——30523—270
B-cell chronic lymphocytic leukemiaD015451—C91.123395—764
MelanomaD008545——38283—362
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_0000340—16424—562
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C50339——441
T-cell lymphomaD016399——1222——432
Lymphoproliferative disordersD008232Orphanet_2442D47.91517——230
Zika virus infectionD000071243—A92.5152——1330
B-cell lymphoma marginal zoneD018442—C88.41018——529
Adenoviridae infectionsD000257EFO_1001259B34.02210——528
Prostatic neoplasmsD011471—C611317——227
GliomaD005910EFO_0000520—199——225
Lung neoplasmsD008175—C34.90196——324
Pancreatic neoplasmsD010190EFO_0003860C25208——124
Show 366 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DermatitisD003872—L30.91———67
Varicella zoster virus infectionD000073618——2———57
Atopic dermatitisD003876EFO_0000274L201———67
OligodendrogliomaD009837EFO_0000631—5———16
EmergenciesD004630——2———46
SuicideD013405——2———35
Smoking cessationD016540EFO_0004319—1———45
Inflammatory bowel diseasesD015212EFO_0003767—1———45
Germ cell and embryonal neoplasmsD009373——4————4
MedulloblastomaD008527——4————4
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnxietyD001007EFO_0005230F41.1————66
Community-acquired pneumoniaD000098968——————55
Sleep initiation and maintenance disordersD007319—F51.01————55
Coronary artery diseaseD003324—I25.1————55
Recreational drug useD000084783——————55
RhinovirusD012229——————55
Critical illnessD016638——————55
Neck painD019547—M54.2————44
Anxiety disordersD001008EFO_0006788F41.1————44
GonorrheaD006069DOID_7551A54————44
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVidarabine
INNvidarabine
Description
Adenine arabinoside is a purine nucleoside in which adenine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. It has a role as an antineoplastic agent, a bacterial metabolite and a nucleoside antibiotic. It is a purine nucleoside and a beta-D-arabinoside. It is functionally related to an adenine.
Classification
Small molecule
Drug classantineoplastics (arabinofuranosyl derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
Identifiers
PDB—
CAS-ID5536-17-4
RxCUI—
ChEMBL IDCHEMBL1090
ChEBI ID45327
PubChem CID21704
DrugBankDB00194
UNII ID3XQD2MEW34 (ChemIDplus, GSRS)
Target
Agency Approved
ADA
ADA
Organism
Homo sapiens
Gene name
ADA
Gene synonyms
ADA1
NCBI Gene ID
Protein name
adenosine deaminase
Protein synonyms
Adenosine aminohydrolase
Uniprot ID
Mouse ortholog
Ada (11486)
adenosine deaminase (P03958)
Alternate
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Vidarabine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,380 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,536 adverse events reported
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