Vercirnon
Vercirnon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against C-C chemokine receptor type 9.
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Commercial
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Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Crohn disease | D003424 | EFO_0000384 | K50 | 4 | 2 | 4 | — | — | 10 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 1 | — | — | — | 1 |
| Colitis | D003092 | EFO_0003872 | K52.9 | — | 1 | — | — | — | 1 |
| Ulcer | D014456 | MPATH_579 | — | — | 1 | — | — | — | 1 |
| Celiac disease | D002446 | EFO_0001060 | K90.0 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Vercirnon |
| INN | vercirnon |
| Description | Vercirnon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against C-C chemokine receptor type 9. |
| Classification | Small molecule |
| Drug class | Chemokine receptor (CCR) antagonists, not antivirals |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2cc[n+]([O-])cc2)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 698394-73-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2178578 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | MWI54OUA12 (ChemIDplus, GSRS) |
Target
Agency Approved
CCR9
CCR9
Organism
Homo sapiens
Gene name
CCR9
Gene synonyms
GPR28
NCBI Gene ID
Protein name
C-C chemokine receptor type 9
Protein synonyms
CDw199, chemokine (C-C motif) receptor 9, G protein-coupled receptor 28, G-protein coupled receptor 28, GPR-9-6
Uniprot ID
Mouse ortholog
Ccr9 (12769)
C-C chemokine receptor type 9 (Q9WUT7)
Alternate
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
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