Veliparib
Veliparib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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105 clinical trials
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Indications Phases 4
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
| Lymphoma | D008223 | — | C85.9 | 1 | — | — | — | — | 1 |
| T-cell lymphoma | D016399 | — | — | 1 | — | — | — | — | 1 |
| Mantle-cell lymphoma | D020522 | — | — | 1 | — | — | — | — | 1 |
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Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Veliparib |
| INN | veliparib |
| Description | Veliparib is a benzimidazole substituted with a carbamoyl group at C-4 and a (2R)-2-methylpyrrolidin-2-yl moiety at C-2. It is a potent, orally bioavailable PARP inhibitor. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. |
| Classification | Small molecule |
| Drug class | poly-ADP-ribose polymerase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@]1(c2nc3c(C(N)=O)cccc3[nH]2)CCCN1 |
Identifiers
| PDB | — |
| CAS-ID | 912444-00-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL506871 |
| ChEBI ID | 62880 |
| PubChem CID | 11960529 |
| DrugBank | DB07232 |
| UNII ID | 01O4K0631N (ChemIDplus, GSRS) |
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600 adverse events reported
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