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Drug ReportsVasopressin
Vasopressin
Pitressin, Vasopressin, Vasostrict (vasopressin) is a protein pharmaceutical. Vasopressin was first approved as Pitressin tannate on 1982-01-01.
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FDA approval date
EMA approval date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Vasopressin, Vasostrict (discontinued: Pitressin, Vasopressin, Vasostrict)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Vasopressin
Tradename
Company
Number
Date
Products
VASOPRESSINAmerican RegentN-212593 RX2020-08-03
2 products, RLD, RS
VASOPRESSIN IN SODIUM CHLORIDE 0.9%BaxterN-217569 RX2023-09-29
2 products, RLD, RS
VASOSTRICTEndoN-204485 RX2014-04-17
4 products, RLD, RS
VASOPRESSIN IN SODIUM CHLORIDE 0.9%Long Grove PharmaceuticalsN-217766 RX2024-07-11
2 products, RLD, RS
Show 2 discontinued
Vasopressin tannate
Tradename
Company
Number
Date
Products
PITRESSIN TANNATEPfizerN-003402 DISCN1982-01-01
1 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
vasopressinANDA2025-08-26
vasopressin in 0.9% sodium chlorideNew Drug Application2025-06-17
vasostrictNew Drug Application2023-11-16
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Vasopressin, Vasostrict, Par Sterile Products
93754782035-01-30U-1857
96875262035-01-30U-1857
97442092035-01-30U-1857
97442392035-01-30U-1857
97507852035-01-30DP
99190262035-01-30DP
99252332035-01-30U-1857
99252342035-01-30U-1857
99372232035-01-30U-1857
99624222035-01-30U-1857
99686492035-01-30U-1857
99748272035-01-30U-1857
99810062035-01-30U-1857
100105752035-01-30U-1857
ATC Codes
C: Cardiovascular system drugs
— C03: Diuretics
— C03X: Other diuretics in atc
— C03XA: Vasopressin antagonists, diuretics
H: Systemic hormonal preparations, excl. sex hormones and insulins
— H01: Pituitary and hypothalamic hormones and analogues
— H01B: Posterior pituitary lobe hormones
— H01BA: Vasopressin and analogues
— H01BA01: Vasopressin (argipressin)
HCPCS
No data
Clinical
Clinical Trials
406 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Diabetes insipidusD003919—E23.261311122967
Septic shockD012772—A48.31111191644
ShockD012769—R57.11131261743
HemorrhageD006470MP_0001914R58—4217730
SyndromeD013577——26103927
HyponatremiaD007010—E87.1—2132926
Liver cirrhosisD008103EFO_0001422K74.0—6461124
Hepatorenal syndromeD006530—K76.71483620
Acute kidney injuryD058186—N17—235919
NocturiaD053158—R35.1—484419
Show 64 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Inappropriate adh syndromeD007177EFO_1000982E22.2136—413
Neurogenic diabetes insipidusD020790——231—511
Kidney diseasesD007674EFO_0003086N08—34—39
Polycystic kidney diseasesD007690—Q61.3—34—28
Autosomal dominant polycystic kidneyD016891EFO_1001496Q61.2—34—28
Liver failureD017093—K72.9—11—57
Diabetes mellitusD003920EFO_0000400E08-E13—21—36
Hepatic insufficiencyD048550————1—45
Critical illnessD016638———11—35
AnesthesiaD000758———11—34
Show 26 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.911——24
Nephrogenic diabetes insipidusD018500—N25.1—1——34
DepressionD003863—F33.911——13
Chronic kidney failureD007676EFO_0003884N18.6—1——23
Hemophilia bD002836—D6711——13
Cerebral hemorrhageD002543———2———2
Traumatic shockD012774—T79.411———2
NephritisD009393—N05—1———1
Neonatal sepsisD000071074———1———1
Respiratory distress syndromeD012128EFO_1000637J80—1———1
Show 19 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———5———1116
Social psychologyD011593——2————2
HypopituitarismD007018EFO_0001380E23.01———12
Anxiety disordersD001008EFO_0006788F41.12————2
Pure autonomic failureD054970——1————1
Prostatic neoplasmsD011471—C611————1
EmbolismD004617——1————1
AtherosclerosisD050197EFO_0003914I25.11————1
Intracranial arteriosclerosisD002537EFO_1000860I67.21————1
FearD005239——1————1
Show 3 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DehydrationD003681—E86.0————44
Acute-on-chronic liver failureD065290——————44
Blood platelet disordersD001791——————22
Type 2 diabetes mellitusD003924EFO_0001360E11————22
Von willebrand diseasesD014842EFO_0003910D68.0————22
Pituitary diseasesD010900—E23.7————22
SchizophreniaD012559EFO_0000692F20————22
Acute liver failureD017114——————22
Meniere diseaseD008575EFO_0006862H81.0————22
Transient ischemic attackD002546EFO_0003764G45.9————22
Show 77 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVasopressin
INNvasopressin injection
Description
Argipressin is the predominant form of mammalian vasopressin (antidiuretic hormone). It is a nonapeptide containing an arginine at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. It has a role as a cardiovascular drug, a hematologic agent and a mitogen. It is a conjugate base of an argipressin(2+).
Classification
Protein
Drug classvasoconstrictors (vasopressin derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
Identifiers
PDB—
CAS-ID113-79-1
RxCUI—
ChEMBL IDCHEMBL373742
ChEBI ID34543
PubChem CID644077
DrugBankDB00067
UNII IDY87Y826H08 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Vasopressin – Eagle Pharmaceuticals
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Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 62,326 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,107 adverse events reported
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