

Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia | D012559 | EFO_0000692 | F20 | — | 1 | 1 | — | — | 1 |
| Drug common name | Varespladib |
| INN | varespladib |
| Description | Varespladib is a member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects. It has a role as an EC 3.1.1.4 (phospholipase A2) inhibitor, an anti-inflammatory drug and an antidote. It is a member of indoles, a member of benzenes, an aromatic ether, a dicarboxylic acid monoamide, a monocarboxylic acid and a primary carboxamide. It is a conjugate acid of a varespladib(1-). |
| Classification | Small molecule |
| Drug class | phospholipase A2 inhibitors |
| Image (chem structure or protein) | ![]() |
| Structure (InChI/SMILES or Protein Sequence) | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 |
| PDB | — |
| CAS-ID | 172732-68-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL148674 |
| ChEBI ID | — |
| PubChem CID | 155815 |
| DrugBank | DB11909 |
| UNII ID | 2Q3P98DATH (ChemIDplus, GSRS) |
