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Drug ReportsVOBARILIZUMAB
VOBARILIZUMAB
Vobarilizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-6 receptor subunit beta.
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Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.9245
ArthritisD001168EFO_0005856M05-M14245
Systemic lupus erythematosusD008180EFO_0002690M3211
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVOBARILIZUMAB
INNvobarilizumab
Description
Vobarilizumab (INN; development code ALX0061) is a humanized bispecific nanobody (Llama-derived heavy-chain only (Vhh) antibody) designed for the treatment of inflammatory autoimmune diseases.
Classification
Antibody
Drug classantiviral (arildone derivatives); monoclonal antibodies
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Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB7XL0
CAS-ID
RxCUI
ChEMBL IDCHEMBL3833343
ChEBI ID
PubChem CID
DrugBank
UNII ID9OD8ISS64U (ChemIDplus, GSRS)
Target
Agency Approved
IL6ST
IL6ST
Organism
Homo sapiens
Gene name
IL6ST
Gene synonyms
NCBI Gene ID
Protein name
interleukin-6 receptor subunit beta
Protein synonyms
CD130, CD130 antigen, CDw130, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, gp130, oncostatin M receptor, IL-6 receptor subunit beta, IL-6R subunit beta, interleukin receptor beta chain, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha
Uniprot ID
Mouse ortholog
Il6st (16195)
interleukin-6 receptor subunit beta (Q00560)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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