VELSECORAT
Velsecorat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target glucocorticoid receptor.
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Events Timeline
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YTD
1Y
2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 6 | 2 | — | — | — | 8 |
| Healthy volunteers/patients | — | — | — | 1 | 1 | — | — | — | 2 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 4 | — | — | — | — | 4 |
| Obstructive lung diseases | D008173 | — | — | 4 | — | — | — | — | 4 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | 2 | — | — | — | — | 2 |
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | VELSECORAT |
| INN | velsecorat |
| Description | Velsecorat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target glucocorticoid receptor. |
| Classification | Small molecule |
| Drug class | glucocorticoid receptor agonists ( not glucocorticoids) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2c(cnn2-c2cccc(C(=O)N[C@@H]3CCOC3)c2)c1)c1ccc2c(c1)OCCO2 |
Identifiers
| PDB | — |
| CAS-ID | 1196509-60-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3666807 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | P30N0911C2 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
NR3C1
NR3C1
Organism
Homo sapiens
Gene name
NR3C1
Gene synonyms
GRL
NCBI Gene ID
Protein name
glucocorticoid receptor
Protein synonyms
Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3 group C member 1 variant hGR-B(54), nuclear receptor subfamily 3 group C member 1 variant hGR-B(77), nuclear receptor subfamily 3 group C member 1 variant hGR-B(93), nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Uniprot ID
Mouse ortholog
Nr3c1 (14815)
glucocorticoid receptor (Q61629)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 26 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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