VALOPICITABINE
Valopicitabine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis c | D006526 | — | B19.2 | 2 | 5 | — | — | — | 5 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 2 | 5 | — | — | — | 5 |
| Hepatitis | D006505 | HP_0012115 | K75.9 | 2 | 5 | — | — | — | 5 |
| Chronic hepatitis | D006521 | — | K73.9 | 2 | 5 | — | — | — | 5 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | 2 | 4 | — | — | — | 4 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | VALOPICITABINE |
| INN | valopicitabine |
| Description | Valopicitabine (NM-283) is an antiviral drug which was developed as a treatment for hepatitis C, though only progressed as far as Phase III clinical trials. It acts as an RNA-dependent RNA polymerase inhibitor. It is a prodrug which is converted inside the body to the active form, 2'-C-methylcytidine triphosphate.
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| Classification | Small molecule |
| Drug class | nucleoside antiviral or antineoplastic agents, cytarabine or azarabine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)[C@H](N)C(=O)O[C@@H]1[C@@H](CO)O[C@@H](n2ccc(N)nc2=O)[C@]1(C)O |
Identifiers
| PDB | — |
| CAS-ID | 640281-90-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL393820 |
| ChEBI ID | — |
| PubChem CID | 6918726 |
| DrugBank | DB13920 |
| UNII ID | I2T0B5G94M (ChemIDplus, GSRS) |
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Safety
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0 adverse events reported
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