Tradename | Proper name | Company | Number | Date | Products |
---|---|---|---|---|---|
Stelara | ustekinumab | Johnson & Johnson | N-125261 RX | 2009-09-25 | 3 products |
Stelara | ustekinumab | Johnson & Johnson | N-761044 RX | 2016-09-23 | 1 products |
Brand Name | Status | Last Update |
---|---|---|
imuldosa | Biologic Licensing Application | 2025-09-02 |
otulfi | Biologic Licensing Application | 2025-06-09 |
pyzchiva | Biologic Licensing Application | 2025-08-04 |
selarsdi | Biologic Licensing Application | 2025-02-28 |
stelara | Biologic Licensing Application | 2025-07-10 |
steqeyma | Biologic Licensing Application | 2025-04-21 |
ustekinumab | Biologic Licensing Application | 2025-04-08 |
ustekinumab-aekn | Biologic Licensing Application | 2025-02-28 |
ustekinumab-ttwe | Biologic Licensing Application | 2025-03-18 |
wezlana | Biologic Licensing Application | 2025-04-01 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Psoriasis | D011565 | EFO_0000676 | L40 | 8 | 4 | 37 | 10 | 19 | 78 |
Crohn disease | D003424 | EFO_0000384 | K50 | 4 | 7 | 15 | 10 | 41 | 75 |
Ulcerative colitis | D003093 | EFO_0000729 | K51 | 1 | 2 | 5 | 3 | 20 | 31 |
Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 1 | 1 | 5 | 3 | 15 | 25 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | 1 | — | 1 |
Netherton syndrome | D056770 | — | — | — | — | — | 1 | — | 1 |
Lamellar ichthyosis | D017490 | — | Q80 | — | — | — | 1 | — | 1 |
Ichthyosis vulgaris | D016112 | — | Q80.0 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Psoriatic arthritis | D015535 | EFO_0003778 | L40.5 | — | 3 | 8 | — | 14 | 25 |
Colitis | D003092 | EFO_0003872 | K52.9 | 1 | 1 | 5 | — | 5 | 12 |
Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | 1 | — | 9 | 10 |
Ulcer | D014456 | MPATH_579 | — | 1 | 2 | 2 | — | 4 | 9 |
Skin diseases | D012871 | — | L00-L99 | — | — | 4 | — | 2 | 6 |
Intestinal diseases | D007410 | — | K63.9 | 1 | 1 | 1 | — | 3 | 5 |
Ankylosing spondylitis | D013167 | EFO_0003898 | M45 | — | 1 | 2 | — | 2 | 5 |
Spondylitis | D013166 | — | M46.9 | — | — | 1 | — | 3 | 4 |
Axial spondyloarthritis | D000089183 | — | — | — | — | 3 | — | 1 | 4 |
Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | — | 1 | 2 | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | 1 | — | — | 4 | 5 |
Inflammation | D007249 | MP_0001845 | — | — | 2 | — | — | 3 | 5 |
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 2 | — | — | 1 | 3 |
Uveitis | D014605 | EFO_1001231 | H20.9 | 1 | 3 | — | — | — | 3 |
Autoimmune diseases | D001327 | EFO_0000540 | M30-M36 | — | 1 | — | — | 1 | 2 |
Giant cell arteritis | D013700 | EFO_1001209 | M31.6 | 1 | 2 | — | — | — | 2 |
Eczema | D004485 | — | L30.9 | — | 2 | — | — | — | 2 |
Graft vs host disease | D006086 | — | D89.81 | — | 1 | — | — | — | 1 |
Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | 1 | — | — | — | 1 |
Bullous pemphigoid | D010391 | EFO_0007187 | L12 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 8 | — | — | — | — | 8 |
Ichthyosis | D007057 | — | E50.8 | 1 | — | — | — | — | 1 |
Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Infections | D007239 | EFO_0000544 | — | — | — | — | — | 2 | 2 |
Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | — | 1 | 1 |
Congenital abnormalities | D000013 | EFO_0003915 | Q89.9 | — | — | — | — | 1 | 1 |
Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
Hepatitis b | D006509 | — | — | — | — | — | — | 1 | 1 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | — | — | 1 | 1 |
Necrosis | D009336 | — | — | — | — | — | — | 1 | 1 |
Pathologic constriction | D003251 | — | — | — | — | — | — | 1 | 1 |
Intestinal obstruction | D007415 | — | K56.60 | — | — | — | — | 1 | 1 |
Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | — | 1 | 1 |
Drug common name | Ustekinumab |
INN | ustekinumab |
Description | Ustekinumab, sold under the brand name Stelara, is a human monoclonal antibody used to treat psoriasis. It is also approved to treat Crohn's disease in the United States, Israel and Australia, and ulcerative colitis in the U.S., and in the European Union (EU) among people who have not responded to more traditional treatments. |
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | >3HMW:H|USTEKINUMAB FAB HEAVY CHAIN
EVQLVQSGAEVKKPGESLKISCKGSGYSFTTYWLGWVRQMPGKGLDWIGIMSPVDSDIRYSPSFQGQVTMSVDKSITTAY
LQWNSLKASDTAMYYCARRRPGQGYFDFWGQGTLVTVSSSSTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW
NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTH
>3HMW:L|USTEKINUMAB FAB LIGHT CHAIN
DIQMTQSPSSLSASVGDRVTITCRASQGISSWLAWYQQKPEKAPKSLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP
EDFATYYCQQYNIYPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
PDB | 3HMW, 3HMX |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL1201835 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB05679 |
UNII ID | FU77B4U5Z0 (ChemIDplus, GSRS) |