Txa127
Txa127 is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target type-2 angiotensin II receptor and proto-oncogene Mas.
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Drug
General
| Drug common name | Txa127 |
| INN | — |
| Description | Ile(5)-angiotensin II (1-7) is an angiotensin compound consisting of the linear heptapeptide sequence L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro. It has a role as a vasodilator agent. It is a tautomer of an Ile(5)-angiotensin II (1-7) dizwitterion. |
| Classification | Protein |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 39386-80-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545347 |
| ChEBI ID | 55438 |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
Variants
No data
Financial
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Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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