Troxerutin
Troxerutin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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179 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 3 | — | — | 1 | 15 | 19 |
| Hemorrhoids | D006484 | EFO_0009552 | K64 | — | — | — | 2 | 4 | 6 |
| Venous insufficiency | D014689 | — | — | — | — | — | 1 | 1 | 2 |
| Diarrhea | D003967 | HP_0002014 | R19.7 | — | — | — | 1 | 1 | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | 1 | 1 | 2 |
| Postoperative complications | D011183 | — | — | — | — | — | 1 | — | 1 |
| Impacted tooth | D014095 | HP_0011079 | K01.1 | — | — | — | 1 | — | 1 |
| Lymphedema | D008209 | HP_0001004 | — | — | — | — | 1 | — | 1 |
| Hyperuricemia | D033461 | HP_0002149 | — | — | — | — | 1 | — | 1 |
| Rectal fistula | D012003 | HP_0010447 | K60.3 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | 1 | — | 7 | 8 |
| Syndrome | D013577 | — | — | — | — | 1 | — | 4 | 5 |
| Postthrombotic syndrome | D054070 | EFO_0007452 | I87.0 | — | — | 2 | — | — | 2 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | 1 | — | 1 | 2 |
| Thrombosis | D013927 | — | — | — | — | 1 | — | — | 1 |
| Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | — | 1 | — | — | 1 |
| Proctitis | D011349 | EFO_0005628 | K62.89 | — | — | 1 | — | — | 1 |
| Postphlebitic syndrome | D011186 | — | I87.0 | — | — | 1 | — | — | 1 |
| Angina pectoris | D000787 | EFO_0003913 | I20 | — | — | 1 | — | — | 1 |
| Stable angina | D060050 | — | I20.89 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammation | D007249 | MP_0001845 | — | 2 | 3 | — | — | 6 | 11 |
| Cardiovascular diseases | D002318 | HP_0001626 | — | 1 | 1 | — | — | 8 | 10 |
| Hypertension | D006973 | EFO_0000537 | I10 | 1 | 1 | — | — | 5 | 7 |
| Covid-19 | D000086382 | — | — | 1 | 1 | — | — | 5 | 7 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | 1 | — | — | 2 | 3 |
| Pediatric obesity | D063766 | — | — | — | 1 | — | — | 1 | 2 |
| Frailty | D000073496 | — | R53.1 | — | 2 | — | — | — | 2 |
| Stomatitis | D013280 | EFO_1001904 | K12.1 | 1 | 1 | — | — | — | 2 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | — | — | — | 2 |
Show 17 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Overweight | D050177 | — | E66.3 | 1 | — | — | — | 3 | 4 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | 2 | — | — | — | 2 | 4 |
| Mental processes | D008606 | EFO_0004323 | — | 1 | — | — | — | 1 | 2 |
| Oxidative stress | D018384 | EFO_1001905 | — | 1 | — | — | — | 1 | 2 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 1 | — | — | — | 1 | 2 |
| Infections | D007239 | EFO_0000544 | — | 1 | — | — | — | — | 1 |
| Hepatitis c | D006526 | — | B19.2 | 1 | — | — | — | — | 1 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 1 | — | — | — | — | 1 |
| Communicable diseases | D003141 | — | — | 1 | — | — | — | — | 1 |
| Hepatitis | D006505 | HP_0012115 | K75.9 | 1 | — | — | — | — | 1 |
Show 21 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | — | — | 7 | 7 |
| Aging | D000375 | GO_0007568 | R41.81 | — | — | — | — | 5 | 5 |
| Affect | D000339 | — | — | — | — | — | — | 5 | 5 |
| Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | — | — | — | 5 | 5 |
| Fatigue | D005221 | HP_0012378 | R53.83 | — | — | — | — | 4 | 4 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 4 | 4 |
| Periodontal pocket | D010514 | EFO_1001393 | — | — | — | — | — | 3 | 3 |
| Coronary disease | D003327 | — | — | — | — | — | — | 3 | 3 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 3 | 3 |
| Sedentary behavior | D057185 | — | — | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Troxerutin |
| INN | troxerutin |
| Description | Troxerutin is a flavonol, a type of flavonoid, derived from rutin. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the Japanese pagoda tree.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(OCCO)c(OCCO)c4)oc4cc(OCCO)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3182320 |
| ChEBI ID | — |
| PubChem CID | 9896814 |
| DrugBank | — |
| UNII ID | 7Y4N11PXO8 (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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158 adverse events reported
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