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Drug ReportsTroriluzole
Troriluzole
Troriluzole is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Target
Variants
Financial
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Obsessive-compulsive disorderD009771EFO_0004242F42—14——4
Compulsive personality disorderD003193—F60.5—14——4
Spinocerebellar ataxiasD020754———12—24
AtaxiaD001259—R27.0——1—23
GlioblastomaD005909EFO_0000515—111——2
RecurrenceD012008———11——1
Anxiety disordersD001008EFO_0006788F41.1——1——1
Generalized anxiety disorderD000098647————1——1
Heart arrestD006323EFO_0009492I46——1——1
Machado-joseph diseaseD017827EFO_0004135———1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MelanomaD008545——11———2
Alzheimer diseaseD000544EFO_0000249F03—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Renal cell carcinomaD002292EFO_0000376—1————1
Non-small-cell lung carcinomaD002289——1————1
LymphomaD008223—C85.91————1
Urinary bladder neoplasmsD001749—C671————1
Hodgkin diseaseD006689—C811————1
Squamous cell carcinoma of head and neckD000077195——1————1
Neoplasm metastasisD009362EFO_0009708—1————1
Cutaneous malignant melanomaD000096142——1————1
Brain neoplasmsD001932EFO_0003833C711————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Spinocerebellar degenerationsD013132—G11————22
Cerebellar ataxiaD002524——————22
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTroriluzole
INNtroriluzole
Description
Troriluzole (trigriluzole) is an experimental medication that has been investigated as a potential treatment for spinocerebellar ataxia type 3 (SCA3), obsessive-compulsive disorder, and glioblastoma. It is a prodrug formulation of the medication riluzole.
Classification
Protein
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CN(CC(=O)Nc1nc2ccc(OC(F)(F)F)cc2s1)C(=O)CNC(=O)CN
Identifiers
PDB—
CAS-ID1926203-09-9
RxCUI—
ChEMBL IDCHEMBL4297586
ChEBI ID—
PubChem CID121488186
DrugBankDB15079
UNII IDS7H48S6K7H (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 116 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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