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Drug ReportsTropisetron
Tropisetron
Tropisetron is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target glycine receptor subunit alpha-2, 5-hydroxytryptamine receptor 4, glycine receptor subunit beta, and glycine receptor subunit alpha-1.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
No data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
A04: Antiemetics and antinauseants
A04A: Antiemetics and antinauseants
A04AA: Serotonin (5ht3) antagonists
A04AA03: Tropisetron
HCPCS
No data
Clinical
No data
Drug
General
Drug common nameTropisetron
INNtropisetron
Description
Tropisetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.
Classification
Small molecule
Drug classserotonin 5-HT3 receptor antagonists; atropine derivatives
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CN1[C@H]2CC[C@@H]1C[C@H](OC(=O)c1c[nH]c3ccccc13)C2
Identifiers
PDB
CAS-ID89565-68-4
RxCUI
ChEMBL IDCHEMBL56564
ChEBI ID32269
PubChem CID72165
DrugBankDB11699
UNII ID6I819NIK1W (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
GLRA2
GLRA2
HTR4
HTR4
GLRB
GLRB
GLRA1
GLRA1
Organism
Homo sapiens
Gene name
GLRA2
Gene synonyms
NCBI Gene ID
Protein name
glycine receptor subunit alpha-2
Protein synonyms
glycine receptor alpha 2 subunit, glycine receptor, alpha-2 polypeptide
Uniprot ID
Mouse ortholog
Glra2 (237213)
glycine receptor subunit alpha-2 (Q7TNC8)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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