Trebananib
Trebananib is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against angiopoietin-2.
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Commercial
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Clinical
Clinical Trials
33 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 1 | 3 | — | — | 6 |
| Fallopian tube neoplasms | D005185 | — | — | 2 | 1 | 3 | — | — | 6 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 2 | — | 3 | — | — | 5 |
| Peritoneal neoplasms | D010534 | — | — | — | 1 | 2 | — | — | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 11 | 2 | — | — | — | 13 |
| Carcinoma | D002277 | — | C80.0 | 3 | 7 | — | — | 1 | 11 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 1 | 3 | — | — | 1 | 5 |
| Recurrence | D012008 | — | — | 2 | 3 | — | — | — | 5 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | — | — | — | 3 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | 1 | — | — | — | 3 |
| Oncogenes | D009857 | — | — | 2 | 1 | — | — | — | 3 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | 2 | — | — | — | 2 |
| Colorectal neoplasms | D015179 | — | — | — | 2 | — | — | — | 2 |
| Hemangiosarcoma | D006394 | — | — | — | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | 1 | — | — | — | — | 1 |
| Carcinoid tumor | D002276 | — | D3A.00 | 1 | — | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | 1 | — | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
| Megakaryoblastic leukemia acute | D007947 | — | C94.2 | 1 | — | — | — | — | 1 |
| Monocytic leukemia acute | D007948 | — | — | 1 | — | — | — | — | 1 |
| Myelomonocytic leukemia acute | D015479 | — | C92.5 | 1 | — | — | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | 1 | — | — | — | — | 1 |
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Trebananib |
| INN | trebananib |
| Description | Trebananib (mab) |
| Classification | Protein |
| Drug class | angiogenesis inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108568 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | X8Y5U6NC7E (ChemIDplus, GSRS) |
Target
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Safety
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106 adverse events reported
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