Transplatin
Transplatin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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FDA
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Brand Name | Status | Last Update |
|---|---|---|
| cisplatin | ANDA | 2024-10-10 |
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Clinical
Clinical Trials
4622 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 172 | 586 | 249 | 6 | 88 | 1014 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 163 | 465 | 233 | 18 | 52 | 850 |
| Non-small-cell lung carcinoma | D002289 | — | — | 147 | 414 | 239 | 21 | 44 | 790 |
| Squamous cell carcinoma | D002294 | — | — | 99 | 310 | 96 | 4 | 42 | 504 |
| Neoplasms | D009369 | — | C80 | 201 | 154 | 48 | 2 | 23 | 370 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 81 | 190 | 67 | 2 | 26 | 335 |
| Head and neck neoplasms | D006258 | — | — | 79 | 182 | 68 | 4 | 34 | 333 |
| Uterine cervical neoplasms | D002583 | HP_0030159 | — | 46 | 123 | 87 | 1 | 41 | 277 |
| Nasopharyngeal carcinoma | D000077274 | — | — | 18 | 135 | 102 | 1 | 27 | 265 |
| Esophageal neoplasms | D004938 | — | C15 | 35 | 154 | 56 | 5 | 20 | 244 |
Show 44 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 50 | 136 | 60 | — | 15 | 235 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 52 | 80 | 35 | — | 18 | 167 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 33 | 103 | 17 | — | 9 | 142 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 32 | 55 | 27 | — | 13 | 118 |
| Mesothelioma | D008654 | — | C45 | 41 | 68 | 11 | — | 6 | 105 |
| Cholangiocarcinoma | D018281 | — | C22.1 | 27 | 61 | 20 | — | 7 | 101 |
| Biliary tract neoplasms | D001661 | — | C24.9 | 25 | 70 | 18 | — | 4 | 99 |
| Malignant mesothelioma | D000086002 | — | — | 39 | 65 | 11 | — | 4 | 98 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 32 | 71 | 9 | — | 4 | 98 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 8 | 37 | 21 | — | 14 | 72 |
Show 156 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Uterine neoplasms | D014594 | EFO_0003859 | C55 | 3 | 7 | — | — | 2 | 11 |
| Papilloma | D010212 | — | — | — | 7 | — | — | 1 | 8 |
| Penile neoplasms | D010412 | — | C60 | 1 | 7 | — | — | — | 8 |
| Glandular and epithelial neoplasms | D009375 | — | — | 2 | 5 | — | — | 1 | 7 |
| Papillomaviridae | D027383 | — | — | — | 5 | — | — | 1 | 6 |
| Colonic neoplasms | D003110 | — | C18 | 3 | 4 | — | — | — | 6 |
| Thyroid neoplasms | D013964 | EFO_0003841 | — | 4 | 4 | — | — | — | 5 |
| Plasmacytoma | D010954 | — | C90.3 | — | 5 | — | — | — | 5 |
| Hyperthermic intraperitoneal chemotherapy | D000084262 | — | — | 2 | 3 | — | — | — | 5 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | 1 | 3 | — | — | 2 | 5 |
Show 147 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Appendiceal neoplasms | D001063 | EFO_0003880 | C18.1 | 2 | — | — | — | 2 | 4 |
| And serous mucinous cystic neoplasms | D018297 | — | — | 1 | — | — | — | — | 1 |
| Hydronephrosis | D006869 | EFO_0005562 | N13.30 | 1 | — | — | — | — | 1 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
| Pinealoma | D010871 | — | — | 1 | — | — | — | — | 1 |
| Primary myelofibrosis | D055728 | — | D47.4 | 1 | — | — | — | — | 1 |
| Medical sociology | D012962 | — | — | 1 | — | — | — | — | 1 |
| Liposarcoma | D008080 | — | — | 1 | — | — | — | — | 1 |
| Vaccinia | D014615 | — | — | 1 | — | — | — | — | 1 |
| Wilms tumor | D009396 | EFO_0000212 | — | 1 | — | — | — | — | 1 |
Show 4 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | — | — | — | 4 | 4 |
| Circulating neoplastic cells | D009360 | — | — | — | — | — | — | 2 | 2 |
| Cervical intraepithelial neoplasia | — | — | D06 | — | — | — | — | 2 | 2 |
| Uterine cervical dysplasia | D002578 | EFO_1000910 | N87 | — | — | — | — | 2 | 2 |
| Chronic periodontitis | D055113 | EFO_0006343 | K05.3 | — | — | — | — | 2 | 2 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 2 | 2 |
| Methylation | D008745 | — | — | — | — | — | — | 1 | 1 |
| Multiple primary neoplasms | D009378 | — | — | — | — | — | — | 1 | 1 |
| Dna damage | D004249 | — | — | — | — | — | — | 1 | 1 |
| Double-stranded dna breaks | D053903 | — | — | — | — | — | — | 1 | 1 |
Show 44 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Transplatin |
| INN | — |
| Description | trans-Dichlorodiammineplatinum(II) is the trans isomer of the coordination complex with the formula trans-PtCl2(NH3)2, sometimes called transplatin. It is a yellow solid with low solubility in water but good solubility in DMF. The existence of two isomers of PtCl2(NH3)2 led Alfred Werner to propose square planar molecular geometry. It belongs to the molecular symmetry point group D2h.
|
| Classification | Small molecule |
| Drug class | antineoplastics (platinum derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 15663-27-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1386 |
| ChEBI ID | 27899 |
| PubChem CID | 5702198 |
| DrugBank | DB00515 |
| UNII ID | — |
Target
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Trends
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Additional graphs summarizing 125,061 documents
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Safety
Black-box Warning
Black-box warning for: Cisplatin
Adverse Events
Top Adverse Reactions
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65,328 adverse events reported
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