Tranimilast
Tranimilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Commercial
No data
Clinical
Clinical Trials
18 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 10 | 3 | 2 | — | — | 15 |
| Obstructive lung diseases | D008173 | — | — | 7 | 1 | 1 | — | — | 9 |
| Chronic bronchitis | D029481 | — | J42 | — | — | 2 | — | — | 2 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | 1 | — | 1 | — | — | 2 |
| Bronchitis | D001991 | — | J40 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | — | 3 | — | — | — | 3 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Respiratory aspiration | D053120 | EFO_1001839 | — | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Tranimilast |
| INN | tanimilast |
| Description | Tranimilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | antiasthmatics/antiallergics (not acting primarily as antihistamines): type IV phosphodiesterase |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CS(=O)(=O)Nc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OCC1CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1239278-59-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3113974 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 0984EU6E2F (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 150 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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