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Drug ReportsTranilast
Tranilast
Tranilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
190 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9246
Respiration disordersD012120J00-J9933
Bronchiolitis obliterans syndromeD000092122D89.81133
Obstructive lung diseasesD008173213
Type 2 diabetes mellitusD003924EFO_0001360E1111
Insulin resistanceD007333EFO_0002614E88.81911
Lung diseasesD008171EFO_0003818J98.411
BronchiectasisD001987J4711
FibrosisD00535511
Cystic fibrosisD003550EFO_0000390E8411
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
PharmacokineticsD01059911
Pharmacological phenomenaD00006943711
Fatty liverD005234EFO_000393411
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTranilast
INNtranilast
Description
Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid.
Classification
Small molecule
Drug classantiasthmatics/antiallergics (not acting primarily as antihistamines)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC
Identifiers
PDB
CAS-ID53902-12-8
RxCUI
ChEMBL IDCHEMBL415324
ChEBI ID77572
PubChem CID5282230
DrugBank
UNII IDHVF50SMY6E (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,776 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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45 adverse events reported
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