Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Depressive disorder | D003866 | EFO_1002014 | F32.A | 10 | 10 | 30 | 16 | 7 | 70 |
Major depressive disorder | D003865 | EFO_0003761 | F22 | 11 | 8 | 28 | 13 | 8 | 66 |
Depression | D003863 | — | F33.9 | 5 | 10 | 29 | 14 | 6 | 61 |
Hot flashes | D019584 | — | — | 2 | — | 3 | 1 | 2 | 8 |
Dysthymic disorder | D019263 | EFO_0008623 | F34.1 | — | 1 | — | 1 | 1 | 3 |
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | — | 1 | 2 | — | 3 |
Pharmacokinetics | D010599 | — | — | — | — | — | 2 | — | 2 |
Anhedonia | D059445 | — | R45.84 | — | — | — | 1 | 1 | 2 |
Generalized anxiety disorder | D000098647 | — | — | — | — | 1 | 1 | — | 2 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | — | 1 | — | — | 4 |
Fibromyalgia | D005356 | EFO_0005687 | M79.1 | 1 | 2 | 1 | — | — | 3 |
Diabetic neuropathies | D003929 | EFO_1000783 | — | 1 | — | 2 | — | — | 3 |
Myofascial pain syndromes | D009209 | EFO_1001054 | — | — | 2 | 1 | — | — | 2 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 2 | 1 | — | — | 2 |
Peripheral nervous system diseases | D010523 | — | G64 | — | — | 2 | — | — | 2 |
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | 1 | 1 | — | — | 1 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | 1 | 1 | — | — | 1 |
Neoplasms | D009369 | — | C80 | — | 1 | 1 | — | — | 1 |
Postpartum depression | D019052 | EFO_0007453 | F53.0 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | — | 1 |
Prediabetic state | D011236 | EFO_1001121 | R73.03 | — | 1 | — | — | — | 1 |
Insulin resistance | D007333 | EFO_0002614 | E88.819 | — | 1 | — | — | — | 1 |
Glucose intolerance | D018149 | HP_0000833 | R73.03 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 1 | 1 |
Acute kidney injury | D058186 | — | N17 | — | — | — | — | 1 | 1 |
Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 1 | 1 |
Cancer pain | D000072716 | — | G89.3 | — | — | — | — | 1 | 1 |
Vomiting | D014839 | — | R11.1 | — | — | — | — | 1 | 1 |
Nausea | D009325 | — | R11.0 | — | — | — | — | 1 | 1 |
Adjustment disorders | D000275 | — | F43.2 | — | — | — | — | 1 | 1 |
Drug common name | Toludesvenlafaxine |
INN | toludesvenlafaxine |
Description | Toludesvenlafaxine, also formerly known as ansofaxine and sold under the brand name Ruoxinlin, is an antidepressant which is approved for the treatment of major depressive disorder in China. It is also under development for use in other countries like the United States. It is a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) and was developed by Luye Pharma Group.
|
Classification | Small molecule |
Drug class | antianxiety, antidepressant inhibitor of norepinephrine and dopamine re-uptake |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Cc1ccc(C(=O)Oc2ccc(C(CN(C)C)C3(O)CCCCC3)cc2)cc1 |
PDB | — |
CAS-ID | 916918-84-8 |
RxCUI | — |
ChEMBL ID | CHEMBL4227736 |
ChEBI ID | — |
PubChem CID | 56955395 |
DrugBank | — |
UNII ID | A7CGH459FN (ChemIDplus, GSRS) |