Vitamin e
Berocca Pn, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitaped (vitamin e) is an unknown pharmaceutical. Vitamin e was first approved as M.v.i.-12 lyophilized on 1985-08-08. It is used to treat alzheimer disease, drug-induced dyskinesia, hemolytic anemia, and vitamin e deficiency in the USA.
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 3 | 15 | 7 | 8 | 12 | 43 |
| Fatty liver | D005234 | EFO_0003934 | — | 1 | 7 | 5 | 8 | 9 | 30 |
| Syndrome | D013577 | — | — | 2 | 7 | 5 | 1 | 10 | 23 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 4 | 2 | 5 | 5 | 6 | 21 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | 1 | 1 | 3 | 6 | 7 | 18 |
| Oxidative stress | D018384 | EFO_1001905 | — | — | 3 | 1 | 1 | 12 | 17 |
| Anemia | D000740 | EFO_0004272 | D64.9 | 2 | 3 | 2 | 1 | 9 | 16 |
| Neoplasms | D009369 | — | C80 | 2 | 2 | 4 | 2 | 6 | 15 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 3 | 2 | 2 | 3 | 6 | 15 |
| Male infertility | D007248 | EFO_0004248 | N46 | 1 | 2 | — | 2 | 9 | 14 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 7 | 3 | 1 | — | 12 | 23 |
| Inflammation | D007249 | MP_0001845 | — | — | 4 | 2 | — | 12 | 16 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | 5 | 5 | — | 7 | 15 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 6 | 1 | — | 6 | 14 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 4 | 3 | — | 6 | 12 |
| Mitochondrial diseases | D028361 | EFO_0000591 | — | 1 | 7 | 3 | — | 3 | 12 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 3 | 4 | — | 2 | 10 |
| Colorectal neoplasms | D015179 | — | — | 1 | 3 | 2 | — | 3 | 9 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | 2 | 1 | — | 6 | 9 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | 1 | 5 | — | 2 | 9 |
Show 146 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 3 | 3 | — | — | 2 | 8 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 3 | — | — | 3 | 6 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 3 | 1 | — | — | 1 | 5 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 3 | — | — | — | 3 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | 3 | — | — | — | 3 |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | — | 1 | — | — | 2 | 3 |
| Autism spectrum disorder | D000067877 | — | F84.0 | — | 1 | — | — | 2 | 3 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 1 | — | — | 2 | 3 |
| Acne vulgaris | D000152 | EFO_0003894 | L70 | — | 1 | — | — | 2 | 3 |
| Adrenoleukodystrophy | D000326 | Orphanet_43 | E71.52 | — | 2 | — | — | — | 2 |
Show 85 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Macular edema | D008269 | — | — | 3 | — | — | — | 1 | 4 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | 1 | — | — | — | 3 | 4 |
| Heart failure | D006333 | EFO_0003144 | I50 | 3 | — | — | — | — | 3 |
| Allergic rhinitis | D065631 | — | J30.9 | 2 | — | — | — | 1 | 3 |
| Rhinitis | D012220 | EFO_0008521 | J31 | 1 | — | — | — | 2 | 3 |
| Female infertility | D007247 | EFO_0008560 | N97 | 1 | — | — | — | 2 | 3 |
| Fatigue | D005221 | — | R53.83 | 1 | — | — | — | 2 | 3 |
| Edema | D004487 | — | R60.9 | 3 | — | — | — | — | 3 |
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | 1 | 2 |
| Sleep apnea syndromes | D012891 | EFO_0003877 | G47.3 | 1 | — | — | — | 1 | 2 |
Show 25 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 9 | 9 |
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | — | — | — | 6 | 6 |
| Joint diseases | D007592 | — | M12.9 | — | — | — | — | 6 | 6 |
| Alopecia | D000505 | — | L64 | — | — | — | — | 5 | 5 |
| Micronutrients | D018977 | — | — | — | — | — | — | 5 | 5 |
| Alopecia areata | D000506 | EFO_0004192 | L63 | — | — | — | — | 4 | 4 |
| Hypotrichosis | D007039 | — | — | — | — | — | — | 4 | 4 |
| Motor activity | D009043 | EFO_0003940 | — | — | — | — | — | 4 | 4 |
| Keratoconjunctivitis sicca | D007638 | EFO_1000906 | — | — | — | — | — | 4 | 4 |
| Skin aging | D015595 | EFO_0005422 | — | — | — | — | — | 4 | 4 |
Show 141 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Vitamin e |
| INN | phytomenadione |
| Description | (R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol. |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 10191-41-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3989727 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | A034SE7857 (ChemIDplus, GSRS) |
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