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Drug ReportsTocopherol
Vitamin e
Berocca Pn, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitaped (vitamin e) is an unknown pharmaceutical. Vitamin e was first approved as M.v.i.-12 lyophilized on 1985-08-08. It is used to treat alzheimer disease, drug-induced dyskinesia, hemolytic anemia, and vitamin e deficiency in the USA.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
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FDA approval date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
hemic and lymphatic diseasesD006425
nutritional and metabolic diseasesD009750
signs and symptoms pathological conditionsD013568
chemically-induced disordersD064419
mental disordersD001523
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.I. PEDIATRICHospiraN-018920 DISCN2000-09-21
1 products, RLD
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin 5'-phosphate sodium
+
Thiamine
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.I.-12 LYOPHILIZEDTeligentN-018933 DISCN1985-08-08
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.I.-12 ADULTHospiraN-008809 DISCN2004-04-22
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.C. 9+3APP PharmaceuticalsN-018440 DISCN1985-08-08
1 products
M.V.I.-12 ADULTHospiraN-008809 DISCN1985-08-08
2 products
MVC PLUSAllerganN-018439 DISCN1985-08-08
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Tradename
Company
Number
Date
Products
M.V.I. ADULTHospiraN-021625 DISCN2004-01-30
1 products, RLD
M.V.I. ADULT (PHARMACY BULK PACKAGE)HospiraN-021643 DISCN2004-02-18
1 products, RLD
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin e
Tradename
Company
Number
Date
Products
BEROCCA PNRocheN-006071 DISCN1985-10-10
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pantothenic acid
+
Phytonadione
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Vitamin a palmitate
+
Vitamin e
Tradename
Company
Number
Date
Products
VITAPEDHospiraN-020176 DISCN1993-12-29
1 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
a and d plus eC2002632024-08-08
acne c-patchunapproved drug other2018-02-10
altra hand sanitizer with aloe and vitamin eC2002632024-07-23
antiphlamineunapproved drug other2017-05-11
anyi beauty vitamin c evens skin tone face serumC2002632024-04-29
astoneaC2002632024-06-25
batana hair oilC2002632024-06-24
batana oil hair care creamC2002632024-05-17
biotnC2002632024-07-09
body milk for stretch marksC2002632024-07-31
Show 56 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
B: Blood and blood forming organ drugs
— B02: Antihemorrhagics
— B02B: Vitamin k and other hemostatics
— B02BA: Vitamin k containing hemostatics
— B02BA01: Phytomenadione
HCPCS
No data
Clinical
Clinical Trials
1334 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369—C8013744630
Knee osteoarthritisD020370EFO_0004616M1711—81827
OsteoarthritisD010003EFO_0002506M15-M19—1—81726
Non-alcoholic fatty liver diseaseD065626EFO_0003095K75.811845925
Colorectal neoplasmsD015179——8731421
Diabetes mellitusD003920HP_0000819E08-E133245619
ObesityD009765EFO_0001073E66.94332818
Oxidative stressD018384EFO_1001905——3111217
Covid-19D000086382—U07.1—531916
Type 2 diabetes mellitusD003924EFO_0001360E116412416
Show 99 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———7042—2398
Cardiovascular diseasesD002318HP_0001626——58—1223
Breast neoplasmsD001943EFO_0003869C50691—521
AnemiaD000740HP_0001903D64.9245—1020
InflammationD007249MP_0001845—121—1518
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9461—718
Hiv infectionsD015658EFO_0000764B20329—115
Prostatic neoplasmsD011471—C61444—214
Alzheimer diseaseD000544EFO_0000249F03524—213
Chronic kidney failureD007676EFO_0003884N18.6—43—612
Show 139 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J4545——312
Pancreatic neoplasmsD010190EFO_0003860C2573——111
Non-small-cell lung carcinomaD002289——73———10
MicronutrientsD018977———1——67
Ovarian neoplasmsD010051EFO_0003893C5643———6
Cystic fibrosisD003550EFO_0000390E84—3——25
Myelodysplastic syndromesD009190—D4632———4
MelanomaD008545——41———4
Hepatitis cD006526—B19.212——14
Beta-thalassemiaD017086Orphanet_848D56.111——34
Show 101 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.92———1113
StrokeD020521EFO_0000712I63.92———57
Iron deficienciesD000090463—E61.11———45
Bacterial infectionsD001424—A492———24
Macular edemaD008269——3———14
FatigueD005221HP_0012378R53.831———34
Non-hodgkin lymphomaD008228—C85.93————3
Neoplasm metastasisD009362EFO_0009708—3————3
Renal cell carcinomaD002292EFO_0000376—3————3
Overactive urinary bladderD053201EFO_1000781N32.813————3
Show 54 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AlopeciaD000505HP_0002293L64————66
ArthralgiaD018771HP_0002829M25.5————55
Hip osteoarthritisD015207EFO_1000786M16————55
ArthritisD001168HP_0001369M05-M14————44
Skin agingD015595EFO_0005422—————44
Musculoskeletal diseasesD009140——————44
Knee prosthesisD007720——————44
Dietary supplementsD019587——————44
AvitaminosisD001361EFO_0005878E56.9————33
RhinitisD012220EFO_0008521J31————33
Show 194 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVitamin e
INNphytomenadione
Description
(R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol.
Classification
Unknown
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID10191-41-0
RxCUI—
ChEMBL IDCHEMBL3989727
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDA034SE7857 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
Black-box warning for: Nestabs one
Adverse Events
Top Adverse Reactions
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2,516 adverse events reported
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