Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Fatty liver | D005234 | EFO_0003934 | — | 3 | 14 | 6 | 9 | 12 | 42 |
Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 2 | 14 | 7 | 8 | 12 | 41 |
Syndrome | D013577 | — | — | 2 | 10 | 6 | 1 | 12 | 28 |
Liver diseases | D008107 | EFO_0001421 | K70-K77 | 2 | 7 | 5 | 6 | 9 | 27 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 4 | 3 | 6 | 5 | 8 | 24 |
Fibrosis | D005355 | — | — | 2 | 10 | 5 | 2 | 3 | 20 |
Infertility | D007246 | EFO_0000545 | — | 2 | 2 | — | 2 | 12 | 18 |
Inflammation | D007249 | MP_0001845 | — | — | 4 | 2 | 1 | 13 | 18 |
Oxidative stress | D018384 | EFO_1001905 | — | — | 3 | 1 | 1 | 12 | 17 |
Male infertility | D007248 | EFO_0004248 | N46 | 1 | 2 | — | 2 | 9 | 14 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 7 | 3 | 1 | — | 12 | 23 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | 5 | 5 | — | 8 | 16 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 6 | 2 | — | 6 | 15 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 4 | 3 | — | 6 | 12 |
Prostatic neoplasms | D011471 | — | C61 | 1 | 3 | 4 | — | 2 | 10 |
Arthritis | D001168 | EFO_0005856 | M05-M14 | 1 | 1 | 1 | — | 7 | 9 |
Colorectal neoplasms | D015179 | — | — | 1 | 3 | 1 | — | 3 | 8 |
Premature birth | D047928 | EFO_0003917 | O60 | 1 | — | 3 | — | 4 | 8 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | 1 | 4 | — | 2 | 8 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | 1 | 1 | — | 6 | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | 2 | — | — | 6 | 8 |
Asthma | D001249 | EFO_0000270 | J45 | 3 | 3 | — | — | 2 | 8 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 3 | — | — | 3 | 6 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 3 | 1 | — | — | 1 | 5 |
Pneumonia | D011014 | EFO_0003106 | J18 | — | 2 | — | — | 2 | 4 |
Acne vulgaris | D000152 | EFO_0003894 | L70 | — | 1 | — | — | 3 | 4 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 3 | — | — | — | 3 |
Ovarian epithelial carcinoma | D000077216 | — | — | 1 | 3 | — | — | — | 3 |
Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | 2 | — | — | 1 | 3 |
Stomatitis | D013280 | EFO_1001904 | K12.1 | — | 1 | — | — | 2 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Heart failure | D006333 | EFO_0003144 | I50 | 3 | — | — | — | 1 | 4 |
Macular edema | D008269 | — | — | 3 | — | — | — | 1 | 4 |
Allergic rhinitis | D065631 | — | J30.9 | 2 | — | — | — | 1 | 3 |
Rhinitis | D012220 | EFO_0008521 | J31 | 1 | — | — | — | 2 | 3 |
Female infertility | D007247 | EFO_0008560 | N97 | 1 | — | — | — | 2 | 3 |
Fatigue | D005221 | — | R53.83 | 1 | — | — | — | 2 | 3 |
Edema | D004487 | — | R60.9 | 3 | — | — | — | — | 3 |
Pharmacokinetics | D010599 | — | — | 1 | — | — | — | 1 | 2 |
Oral lichen planus | D017676 | — | — | 1 | — | — | — | 1 | 2 |
Lichen planus | D008010 | — | L43 | 1 | — | — | — | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 9 | 9 |
Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | — | — | — | 6 | 6 |
Alopecia areata | D000506 | EFO_0004192 | L63 | — | — | — | — | 5 | 5 |
Alopecia | D000505 | — | L64 | — | — | — | — | 5 | 5 |
Micronutrients | D018977 | — | — | — | — | — | — | 5 | 5 |
Hypotrichosis | D007039 | — | — | — | — | — | — | 4 | 4 |
Skin aging | D015595 | EFO_0005422 | — | — | — | — | — | 4 | 4 |
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 4 | 4 |
Joint diseases | D007592 | — | M12.9 | — | — | — | — | 4 | 4 |
Anxiety | D001007 | EFO_0005230 | F41.1 | — | — | — | — | 3 | 3 |
Drug common name | Vitamin e |
INN | phytomenadione |
Description | (R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol. |
Classification | Unknown |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | 10191-41-0 |
RxCUI | — |
ChEMBL ID | CHEMBL3989727 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | A034SE7857 (ChemIDplus, GSRS) |