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Drug ReportsTocopherol
Vitamin e
Berocca Pn, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitaped (vitamin e) is an unknown pharmaceutical. Vitamin e was first approved as M.v.i.-12 lyophilized on 1985-08-08. It is used to treat alzheimer disease, drug-induced dyskinesia, hemolytic anemia, and vitamin e deficiency in the USA.
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-alcoholic fatty liver diseaseD065626EFO_0003095K75.81316781244
Fatty liverD005234EFO_0003934—1758930
SyndromeD013577——26511022
Diabetes mellitusD003920EFO_0000400E08-E133255721
Liver diseasesD008107EFO_0001421K70-K771236719
Oxidative stressD018384EFO_1001905——3111217
AnemiaD000740EFO_0004272D64.92321916
ObesityD009765EFO_0001073E66.93223615
Type 2 diabetes mellitusD003924EFO_0001360E112424415
Male infertilityD007248EFO_0004248N4612—2914
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Indications Phases 3
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Healthy volunteers/patients———731—1324
Cardiovascular diseasesD002318EFO_0000319I98—55—816
InflammationD007249MP_0001845——31—1316
Breast neoplasmsD001943EFO_0003869C50161—513
Chronic kidney failureD007676EFO_0003884N18.6—43—612
Mitochondrial diseasesD028361EFO_0000591—173—312
Prostatic neoplasmsD011471—C61134—210
Colorectal neoplasmsD015179——132—39
MalnutritionD044342EFO_0008572E40-E46—21—69
Alzheimer diseaseD000544EFO_0000249F03115—29
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Indications Phases 2
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AsthmaD001249EFO_0000270J4533——28
Cystic fibrosisD003550EFO_0000390E84—3——36
Pancreatic neoplasmsD010190EFO_0003860C2531——15
Ovarian neoplasmsD010051EFO_0003893C5613———3
Non-small-cell lung carcinomaD002289———3———3
Autistic disorderD001321EFO_0003758F84.0—1——23
Autism spectrum disorderD000067877—F84.0—1——23
Depressive disorderD003866EFO_1002014F32.A—1——23
DementiaD003704EFO_0003862F0311——13
Acne vulgarisD000152EFO_0003894L70—1——23
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Indications Phases 1
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Macular edemaD008269——3———14
HypersensitivityD006967EFO_0003785T78.401———34
Heart failureD006333EFO_0003144I503————3
Allergic rhinitisD065631—J30.92———13
RhinitisD012220EFO_0008521J311———23
Female infertilityD007247EFO_0008560N971———23
FatigueD005221—R53.831———23
EdemaD004487—R60.93————3
PharmacokineticsD010599——1———12
Sleep apnea syndromesD012891EFO_0003877G47.31———12
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Indications Without Phase
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OsteoarthritisD010003EFO_0002506M15-M19————99
ArthritisD001168EFO_0005856M05-M14————77
Hip osteoarthritisD015207EFO_1000786M16————66
Motor activityD009043EFO_0003940—————55
AlopeciaD000505—L64————55
MicronutrientsD018977——————55
Skin agingD015595EFO_0005422—————55
Alopecia areataD000506EFO_0004192L63————44
HypotrichosisD007039——————44
Keratoconjunctivitis siccaD007638EFO_1000906—————44
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVitamin e
INNphytomenadione
Description
(R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol.
Classification
Unknown
Drug class—
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID10191-41-0
RxCUI—
ChEMBL IDCHEMBL3989727
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDA034SE7857 (ChemIDplus, GSRS)
Target
No data
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2,645 adverse events reported
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