Tiratricol
Tiratricol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target thyroid hormone receptor alpha and thyroid hormone receptor beta.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| childrens triacting nighttime | C200263 | 2023-10-13 |
| natural peeling triactive acne | OTC monograph final | 2016-11-01 |
| triacin-c | ANDA | 2015-07-28 |
| triacting daytime cold cough | C200263 | 2024-05-15 |
| vistogard | New Drug Application | 2024-07-23 |
| xuriden | New Drug Application | 2024-05-17 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D11: Other dermatological preparations in atc
— D11A: Other dermatological preparations in atc
— D11AX: Other dermatological preparations in atc
— D11AX08: Tiratricol
H: Systemic hormonal preparations, excl. sex hormones and insulins
— H03: Thyroid therapy drugs
— H03A: Thyroid preparations
— H03AA: Thyroid hormones
— H03AA04: Tiratricol
HCPCS
No data
Clinical
Clinical Trials
724 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 3 | — | — | — | — | 3 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 3 | — | — | — | — | 3 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 3 | — | — | — | — | 3 |
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Common cold | D003139 | EFO_0007214 | J00 | 1 | — | — | — | — | 1 |
| Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
| Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | 1 | — | — | — | — | 1 |
| Cognition disorders | D003072 | — | — | 1 | — | — | — | — | 1 |
| Neurocognitive disorders | D019965 | — | F09 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | — | — | 1 | 1 |
| Back pain | D001416 | HP_0003418 | M54 | — | — | — | — | 1 | 1 |
| Anaphylaxis | D000707 | — | T88.6 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Tiratricol |
| INN | tiratricol |
| Description | Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue. Triiodothyroacetic acid is also a physiologic thyroid hormone that is present in the normal organism in low concentrations.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1 |
Identifiers
| PDB | — |
| CAS-ID | 51-24-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL41632 |
| ChEBI ID | — |
| PubChem CID | 5803 |
| DrugBank | DB03604 |
| UNII ID | 29OQ9EU4R1 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
THRA
THRA
Organism
Homo sapiens
Gene name
THRA
Gene synonyms
EAR7, ERBA1, NR1A1, THRA1, THRA2
NCBI Gene ID
Protein name
thyroid hormone receptor alpha
Protein synonyms
c-erbA protooncogene, c-erbA-1, c-erbA-alpha, EAR-7, ERBA-related 7, Nuclear receptor subfamily 1 group A member 1, thyroid hormone receptor alpha 1, thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), triiodothyronine receptor, V-erbA-related protein 7
Uniprot ID
Mouse ortholog
Thra (21833)
thyroid hormone receptor alpha (Q99146)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 675 documents
View more details
Safety
Black-box Warning
Black-box warning for: Triacin-c
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
58 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use