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Drug ReportsTiclopidine
Ticlopidine
Ticlid (ticlopidine) is a small molecule pharmaceutical. Ticlopidine was first approved as Ticlid on 1991-10-31. It is used to treat intracranial embolism and thrombosis in the USA. It is known to target cytochrome P450 2B6.
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FDA approval date
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Study first post date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
cardiovascular diseasesD002318
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ticlopidine hydrochloride
Tradename
Company
Number
Date
Products
TICLIDRocheN-019979 DISCN1991-10-31
2 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
ticlopidine hydrochlorideANDA2016-08-06
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
intracranial embolism and thrombosis—D002542—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
B: Blood and blood forming organ drugs
— B01: Antithrombotic agents
— B01A: Antithrombotic agents
— B01AC: Platelet aggregation inhibitors excl. heparin
— B01AC05: Ticlopidine
HCPCS
Code
Description
G9531
Patient has documentation of ventricular shunt, brain tumor, multisystem trauma, or is currently taking an antiplatelet medication including: abciximab, anagrelide, cangrelor, cilostazol, clopidogrel, dipyridamole, eptifibatide, prasugrel, ticlopidine, ticagrelor, tirofiban, or vorapaxar
Clinical
Clinical Trials
715 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———2————2
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTiclopidine
INNticlopidine
Description
Ticlopidine is a thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group. It has a role as a fibrin modulating drug, a hematologic agent, an anticoagulant, a platelet aggregation inhibitor and a P2Y12 receptor antagonist. It is a thienopyridine and a member of monochlorobenzenes.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
Clc1ccccc1CN1CCc2sccc2C1
Identifiers
PDB—
CAS-ID55142-85-3
RxCUI—
ChEMBL IDCHEMBL833
ChEBI ID9588
PubChem CID5472
DrugBankDB00208
UNII IDOM90ZUW7M1 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
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Estimated US medical usage
Ticlopidine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 6,685 documents
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Safety
Black-box Warning
Black-box warning for: Ticlopidine hydrochloride
Adverse Events
Top Adverse Reactions
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1,434 adverse events reported
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