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Drug ReportsTiclopidine
Ticlopidine
Ticlid (ticlopidine) is a small molecule pharmaceutical. Ticlopidine was first approved as Ticlid on 1991-10-31. It is used to treat intracranial embolism and thrombosis in the USA. It is known to target cytochrome P450 2B6.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
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YTD
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2Y
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FDA approval date
EMA approval date
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Study first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
cardiovascular diseasesD002318
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ticlopidine hydrochloride
Tradename
Company
Number
Date
Products
TICLIDRocheN-019979 DISCN1991-10-31
2 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
ticlopidine hydrochlorideANDA2016-08-06
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
intracranial embolism and thrombosisD002542
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
B: Blood and blood forming organ drugs
B01: Antithrombotic agents
B01A: Antithrombotic agents
B01AC: Platelet aggregation inhibitors excl. heparin
B01AC05: Ticlopidine
HCPCS
Code
Description
G9531
Patient has documentation of ventricular shunt, brain tumor, multisystem trauma, or is currently taking an antiplatelet medication including: abciximab, anagrelide, cangrelor, cilostazol, clopidogrel, dipyridamole, eptifibatide, prasugrel, ticlopidine, ticagrelor, tirofiban, or vorapaxar
Clinical
Clinical Trials
717 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Coronary artery diseaseD003324I25.17192810622176
Acute coronary syndromeD054058EFO_0005672812284516107
Myocardial infarctionD009203EFO_0000612I2151838766
Coronary diseaseD0033277639958
Ischemic strokeD0000832422723171257
StrokeD020521EFO_0000712I63.9824161154
Myocardial ischemiaD017202EFO_1001375I20-I257636754
Healthy volunteers/patients4014247
ThrombosisD013927241012735
Percutaneous coronary interventionD06264515815835
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Indications Phases 3
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Head and neck neoplasmsD006258112
HivD006678O98.7112
Blood platelet disordersD001791112
Coronavirus infectionsD018352EFO_0007224B34.211
Respiratory insufficiencyD012131J96.911
Viral pneumoniaD011024EFO_0007541J12.911
Cognition disordersD00307211
Hiv infectionsD015658EFO_0000764B2011
Lung diseasesD008171EFO_0003818J98.411
Obstructive lung diseasesD00817311
Show 13 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Therapeutic equivalencyD01381022
FastingD005215EFO_000275622
HemostasisD00648722
Depressive disorderD003866EFO_1002014F32.A112
Acquired immunodeficiency syndromeD000163EFO_0000765B2011
Crush injuriesD000071576T14.811
Major depressive disorderD003865EFO_0003761F2211
Hemolytic anemiaD000743D55-D5911
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pulmonary embolismD011655EFO_0003827I2644
Hip fracturesD006620EFO_0003964S72.0022
Asymptomatic diseasesD05807022
Cerebrovascular disordersD002561EFO_0003763I60-I6922
Coronary occlusionD054059I2111
Cerebral amyloid angiopathyD016657EFO_0006790I68.011
Familial cerebral amyloid angiopathyD02824311
Surgical blood lossD01606311
HyperuricemiaD03346111
Leg ulcerD00787111
Show 24 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTiclopidine
INNticlopidine
Description
Ticlopidine is a thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group. It has a role as a fibrin modulating drug, a hematologic agent, an anticoagulant, a platelet aggregation inhibitor and a P2Y12 receptor antagonist. It is a thienopyridine and a member of monochlorobenzenes.
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Clc1ccccc1CN1CCc2sccc2C1
Identifiers
PDB
CAS-ID55142-85-3
RxCUI
ChEMBL IDCHEMBL833
ChEBI ID9588
PubChem CID5472
DrugBankDB00208
UNII IDOM90ZUW7M1 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
No data
Estimated US medical usage
Ticlopidine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 6,714 documents
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Safety
Black-box Warning
Black-box warning for: Ticlopidine hydrochloride
Adverse Events
Top Adverse Reactions
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1,434 adverse events reported
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