Ticarcillin
Ticar, Timentin (ticarcillin) is a small molecule pharmaceutical. Ticarcillin was first approved as Ticar on 1982-01-01. It is used to treat bacterial infections, infectious skin diseases, pseudomonas infections, respiratory tract infections, and soft tissue infections amongst others in the USA.
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Commercial
Therapeutic Areas
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Ticarcillin disodium
Labels
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Agency Specific
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ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CA: Penicillins with extended spectrum
— J01CA13: Ticarcillin
— J01CR: Combinations of penicillins, incl. beta-lactamase inhibitors
— J01CR03: Ticarcillin and beta-lactamase inhibitor
HCPCS
Code | Description |
|---|---|
| S0040 | Injection, ticarcillin disodium and clavulanate potassium, 3.1 grams |
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fibrosis | D005355 | — | — | — | — | — | 1 | 1 | 2 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | 1 | 1 | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 2 | 1 | — | — | 3 |
| Bacterial skin diseases | D017192 | — | — | — | — | 1 | — | — | 1 |
| Skin diseases | D012871 | — | L00-L99 | — | — | 1 | — | — | 1 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | 1 | 1 | — | — | 1 |
| Disease progression | D018450 | — | — | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Communicable diseases | D003141 | — | — | — | 2 | — | — | — | 2 |
| Intraabdominal infections | D059413 | — | — | — | 1 | — | — | — | 1 |
| Pelvic infection | D034161 | — | — | — | 1 | — | — | — | 1 |
| Pelvic inflammatory disease | D000292 | EFO_1001388 | N70-N77 | — | 1 | — | — | — | 1 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sepsis | D018805 | HP_0100806 | A41.9 | 2 | — | — | — | — | 2 |
| Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic bronchitis | D029481 | — | J42 | — | — | — | — | 1 | 1 |
| Bronchitis | D001991 | — | J40 | — | — | — | — | 1 | 1 |
| Disease susceptibility | D004198 | — | — | — | — | — | — | 1 | 1 |
| Appendicitis | D001064 | EFO_0007149 | K37 | — | — | — | — | 1 | 1 |
| Bacterial infections | D001424 | — | A49 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ticarcillin |
| INN | ticarcillin |
| Description | Ticarcillin is a penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a ticarcillin(2-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C(=O)O)c3ccsc3)C(=O)N2[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 34787-01-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1449 |
| ChEBI ID | 9587 |
| PubChem CID | 36921 |
| DrugBank | DB01607 |
| UNII ID | F93UJX4SWT (ChemIDplus, GSRS) |
Target
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Safety
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Adverse Events
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300 adverse events reported
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