Thymalfasin
Thymalfasin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
65 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | 1 | 2 | 1 | 2 | — | 5 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | — | 1 | 1 | 3 | 5 |
| Hepatitis b | D006509 | — | — | — | 1 | 1 | 2 | — | 4 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | — | 1 | — | 2 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | 2 | — | 2 |
| Toxemia | D014115 | — | — | — | — | — | 1 | 1 | 2 |
| Pancreatitis | D010195 | EFO_0000278 | K85 | — | — | — | 1 | — | 1 |
| Acute necrotizing pancreatitis | D019283 | — | — | — | — | — | 1 | — | 1 |
| Musculoskeletal pain | D059352 | — | — | — | — | — | 1 | — | 1 |
| Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis | D006505 | — | K75.9 | — | 1 | 3 | — | — | 4 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | — | 1 | 3 | — | — | 4 |
| Colorectal neoplasms | D015179 | — | — | — | 1 | 1 | — | 1 | 3 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | — | — | 3 | — | — | 3 |
| Covid-19 | D000086382 | — | U07.1 | — | 2 | 1 | — | — | 3 |
| Hepatitis c | D006526 | — | B19.2 | — | — | 2 | — | — | 2 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 6 | — | — | 2 | 8 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | 4 | — | — | 1 | 5 |
| Small cell lung carcinoma | D055752 | — | — | 1 | 3 | — | — | — | 3 |
| Melanoma | D008545 | — | — | — | 2 | — | — | — | 2 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | 1 | 2 |
| Lymphopenia | D008231 | — | D72.810 | — | 2 | — | — | — | 2 |
| Esophageal neoplasms | D004938 | — | C15 | — | 2 | — | — | — | 2 |
| Radiotherapy | D011878 | — | — | — | 2 | — | — | — | 2 |
| Hematologic neoplasms | D019337 | — | — | 1 | 2 | — | — | — | 2 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | — | — | — | — | 2 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 1 | — | — | — | — | 1 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | — | — | — | — | 1 |
| Uterine cervical neoplasms | D002583 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aortic dissection | D000784 | — | I71.0 | — | — | — | — | 3 | 3 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 2 | 2 |
| Liver failure | D017093 | — | K72.9 | — | — | — | — | 1 | 1 |
| Acute aortic syndrome | D000094683 | — | — | — | — | — | — | 1 | 1 |
| Cardiopulmonary bypass | D002315 | — | — | — | — | — | — | 1 | 1 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 1 | 1 |
| Rheumatic heart disease | D012214 | EFO_1001161 | I09.9 | — | — | — | — | 1 | 1 |
| Immunotherapy | D007167 | — | — | — | — | — | — | 1 | 1 |
| Rheumatic diseases | D012216 | — | M79.0 | — | — | — | — | 1 | 1 |
| Squamous cell carcinoma | D002294 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Thymalfasin |
| INN | thymalfasin |
| Description | THYMALFASIN |
| Classification | Protein |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(C)=O)C(C)C)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)O)C(C)C)C(C)C)[C@@H](C)O)[C@@H](C)O |
Identifiers
| PDB | — |
| CAS-ID | 62304-98-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2103979 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | W0B22ISQ1C (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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45 adverse events reported
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