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Drug ReportsThonzonium
Thonzonium
Coly-mycin (thonzonium) is a small molecule pharmaceutical. Thonzonium was first approved as Coly-mycin s on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Combinations
Coly-mycin
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Colistin sulfate
+
Hydrocortisone acetate
+
Neomycin sulfate
+
Thonzonium bromide
Tradename
Company
Number
Date
Products
COLY-MYCIN SEndoN-050356 RX1982-01-01
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
cortisporin tcNew Drug Application2024-08-01
cortisporin-tcNew Drug Application2010-01-29
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
shock—D012769R57.1
ulcerative colitisEFO_0000729D003093K51
pruritus ani—D011538L29.0
inflammationMP_0001845D007249—
adrenal insufficiency—D000309—
bacterial infections—D001424A49
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
rheumatic diseases—D012216M79.0
status asthmaticus—D013224—
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Agency Specific
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Clinical
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Drug
General
Drug common nameThonzonium
INNtonzonium bromide
Description
Thonzonium bromide is a monocationic detergent. A solution of it is thus a surfactant and a detergent that promotes tissue contact by dispersion and penetration of the cellular debris and exudate of the containing solution.
Classification
Small molecule
Drug classquaternary ammonium derivatives; quaternary ammonium derivatives
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Structure (InChI/SMILES or Protein Sequence)
CCCCCCCCCCCCCCCC[N+](C)(C)CCN(Cc1ccc(OC)cc1)c1ncccn1
Identifiers
PDB—
CAS-ID553-08-2
RxCUI—
ChEMBL IDCHEMBL1201322
ChEBI ID—
PubChem CID11102
DrugBank—
UNII IDJI2B19CR0R (ChemIDplus, GSRS)
Target
No data
Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 145 documents
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Safety
Black-box Warning
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11 adverse events reported
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