Thiazides
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450 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | 16 | 15 | 82 | 110 | 58 | 279 |
| Essential hypertension | D000075222 | — | I10 | 4 | 5 | 29 | 12 | 5 | 53 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 5 | 6 | 1 | 13 | 7 | 32 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 5 | 5 | 2 | 11 | 4 | 27 |
| Heart failure | D006333 | EFO_0003144 | I50 | 2 | 1 | 4 | 9 | 8 | 23 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 1 | 2 | 7 | 4 | 15 |
| Chronic renal insufficiency | D051436 | — | N18 | 1 | 1 | 1 | 8 | 3 | 14 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 6 | 3 | 5 | 14 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 3 | 5 | 1 | 2 | — | 11 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | 2 | — | — | 8 | — | 10 |
Show 54 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 31 | — | 1 | — | 8 | 40 |
| Nephrolithiasis | D053040 | — | N20.0 | — | 2 | 2 | — | 3 | 6 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | 1 | — | 4 | 5 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | 1 | — | 2 | — | 2 | 5 |
| Hyperinsulinism | D006946 | — | E16.1 | 3 | 1 | 1 | — | — | 5 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | 2 | — | — | 2 |
| Neoplasms | D009369 | — | C80 | — | — | 2 | — | — | 2 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | 1 | — | 1 | 2 |
| Acute kidney injury | D058186 | — | N17 | — | — | 1 | — | 1 | 2 |
| Hypercholesterolemia | D006937 | — | — | — | — | 1 | — | — | 1 |
Show 15 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cognitive dysfunction | D060825 | — | G31.84 | — | 1 | — | — | 4 | 5 |
| Hypercalciuria | D053565 | — | R82.994 | — | 1 | — | — | 4 | 5 |
| Ischemic stroke | D000083242 | — | — | — | 1 | — | — | 3 | 4 |
| Aging | D000375 | GO_0007568 | R41.81 | — | 2 | — | — | 1 | 3 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | 2 | 1 | — | — | — | 3 |
| Ischemia | D007511 | EFO_0000556 | — | — | 1 | — | — | 2 | 3 |
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | — | 1 | — | — | 1 | 2 |
| Critical illness | D016638 | — | — | — | 1 | — | — | 1 | 2 |
| Sedentary behavior | D057185 | — | — | — | 1 | — | — | — | 1 |
| Sexual infantilism | D050035 | — | — | — | 1 | — | — | — | 1 |
Show 6 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 4 | — | — | — | — | 4 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | 2 | — | — | — | 2 | 4 |
| Fasting | D005215 | EFO_0002756 | — | 2 | — | — | — | — | 2 |
| Endocrine system diseases | D004700 | EFO_0001379 | E34.9 | 1 | — | — | — | 1 | 2 |
| Myocardial stunning | D017682 | — | — | 2 | — | — | — | — | 2 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 2 | — | — | — | — | 2 |
| Pure autonomic failure | D054970 | — | — | 1 | — | — | — | — | 1 |
| Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
| Chronic pain | D059350 | — | — | 1 | — | — | — | — | 1 |
| Photosensitivity disorders | D010787 | — | L57.1 | 1 | — | — | — | — | 1 |
Show 2 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyponatremia | D007010 | — | E87.1 | — | — | — | — | 4 | 4 |
| Gitelman syndrome | D053579 | Orphanet_358 | N15.8 | — | — | — | — | 2 | 2 |
| Disease | D004194 | EFO_0000408 | R69 | — | — | — | — | 2 | 2 |
| Diastolic heart failure | D054144 | EFO_1000899 | I50.30 | — | — | — | — | 2 | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 1 | 1 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 1 | 1 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | — | 1 | 1 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
| Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 1 | 1 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 1 | 1 |
Show 45 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | — |
| INN | — |
| Description | — |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | — |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
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31 adverse events reported
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