Thalomid, Thalidomide bms (previously thalidomide celgene)(thalidomide)
Thalidomide, Thalomid (thalidomide) is a small molecule pharmaceutical. Thalidomide was first approved as Thalomid on 1998-07-16. It is used to treat aphthous stomatitis, behcet syndrome, crohn disease, discoid lupus erythematosus, and erythema multiforme amongst others in the USA. It has been approved in Europe to treat multiple myeloma. It is known to target protein cereblon.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Show 4 more
Trade Name
FDA
EMA
Thalomid (discontinued: Thalidomide)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Thalidomide
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| THALOMID | Bristol Myers Squibb | N-020785 RX | 1998-07-16 | 4 products, RLD |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| thalomid | New Drug Application | 2023-03-24 |
Indications
FDA
EMA
Show 3 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
527 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 26 | 93 | 61 | 4 | 15 | 182 |
| Plasma cell neoplasms | D054219 | — | — | 25 | 86 | 58 | 4 | 14 | 171 |
| Lymphoma | D008223 | — | C85.9 | 4 | 25 | 3 | 2 | 1 | 33 |
| Syndrome | D013577 | — | — | 2 | 19 | 2 | 1 | 1 | 24 |
| Myelodysplastic syndromes | D009190 | — | D46 | 3 | 14 | 2 | 1 | 2 | 21 |
| Preleukemia | D011289 | — | — | 3 | 14 | 2 | 1 | — | 19 |
| Non-small-cell lung carcinoma | D002289 | — | — | 2 | 11 | 3 | 1 | — | 15 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 2 | 9 | 3 | 1 | — | 14 |
| Thalassemia | D013789 | EFO_1001996 | D56 | 1 | 8 | 4 | 1 | — | 11 |
| Amyloidosis | D000686 | EFO_1001875 | E85 | 1 | 7 | 1 | 1 | 1 | 10 |
Show 29 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 9 | 15 | 5 | — | — | 27 |
| Leukemia | D007938 | — | C95 | 4 | 18 | 2 | — | 3 | 24 |
| Plasmacytoma | D010954 | — | C90.3 | 1 | 14 | 5 | — | 1 | 21 |
| Carcinoma | D002277 | — | C80.0 | 3 | 14 | 6 | — | 1 | 17 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 14 | 6 | — | 1 | 17 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 2 | 11 | 6 | — | 1 | 14 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 12 | 1 | — | — | 13 |
| Crohn disease | D003424 | EFO_0000384 | K50 | 1 | 2 | 3 | — | 4 | 9 |
| Primary myelofibrosis | D055728 | — | D47.4 | — | 6 | 2 | — | — | 8 |
| Colorectal neoplasms | D015179 | — | — | 1 | 6 | 1 | — | — | 8 |
Show 44 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 4 | 11 | — | — | 1 | 13 |
| Central nervous system neoplasms | D016543 | — | — | 2 | 11 | — | — | — | 13 |
| Nervous system neoplasms | D009423 | — | — | 1 | 11 | — | — | — | 12 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 7 | — | — | 3 | 12 |
| Recurrence | D012008 | — | — | — | 10 | — | — | 1 | 11 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 4 | 9 | — | — | 1 | 11 |
| Melanoma | D008545 | — | — | 3 | 9 | — | — | — | 11 |
| Lymphoid leukemia | D007945 | — | C91 | 2 | 8 | — | — | 1 | 9 |
| Sarcoma | D012509 | — | — | — | 8 | — | — | — | 8 |
| Glioma | D005910 | EFO_0000520 | — | 2 | 6 | — | — | — | 8 |
Show 138 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 5 | — | — | — | — | 5 |
| Therapeutic equivalency | D013810 | — | — | 2 | — | — | — | — | 2 |
| Liposarcoma | D008080 | — | — | 1 | — | — | — | — | 1 |
| Intestinal neoplasms | D007414 | — | C26.0 | 1 | — | — | — | — | 1 |
| Pulmonary sarcoidosis | D017565 | DOID_13406 | D86.0 | 1 | — | — | — | — | 1 |
| Osteosarcoma | D012516 | — | — | 1 | — | — | — | — | 1 |
| Retinoblastoma | D012175 | — | — | 1 | — | — | — | — | 1 |
| Ewing sarcoma | D012512 | EFO_0000173 | — | 1 | — | — | — | — | 1 |
| Rhabdomyosarcoma | D012208 | — | — | 1 | — | — | — | — | 1 |
| Primitive neuroectodermal tumors | D018242 | — | — | 1 | — | — | — | — | 1 |
Show 7 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hematopoietic stem cell transplantation | D018380 | — | — | — | — | — | — | 3 | 3 |
| Bone marrow transplantation | D016026 | — | — | — | — | — | — | 1 | 1 |
| Adrenoleukodystrophy | D000326 | Orphanet_43 | E71.52 | — | — | — | — | 1 | 1 |
| Mothers | D009035 | — | — | — | — | — | — | 1 | 1 |
| Carpal tunnel syndrome | D002349 | EFO_0004143 | G56.0 | — | — | — | — | 1 | 1 |
| Leukapheresis | D007937 | — | — | — | — | — | — | 1 | 1 |
| Acute-phase reaction | D000210 | — | — | — | — | — | — | 1 | 1 |
| Survivorship | D000073859 | — | — | — | — | — | — | 1 | 1 |
| Chronic pain | D059350 | HP_0012532 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Thalidomide |
| INN | thalidomide |
| Description | 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione is a dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group. It is a member of piperidones and a member of phthalimides. |
| Classification | Small molecule |
| Drug class | thalidomide derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1 |
Identifiers
| PDB | — |
| CAS-ID | 1012310-87-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL468 |
| ChEBI ID | 74947 |
| PubChem CID | 5426 |
| DrugBank | DB01041 |
| UNII ID | 4Z8R6ORS6L (ChemIDplus, GSRS) |
Target
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Thalomid – Celgene
Mock data
Subscribe for the real data
Subscribe for the real data
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 57,955 documents
View more details
Safety
Black-box Warning
Black-box warning for: Thalomid
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
37,027 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use