Terconazole
Terconazole (terconazole) is a small molecule pharmaceutical. Terconazole was first approved as Terazol 7 on 1987-12-31. It is used to treat mycoses and vulvovaginal candidiasis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| urogenital diseases | D000091642 |
Trade Name
FDA
EMA
Terconazole (discontinued: Terazol, Terconazole)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Terconazole
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| TERCONAZOLE | Fougera Pharmaceuticals | N-021735 RX | 2004-10-01 | 1 products, RLD, RS |
Show 3 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| fungistat max | OTC monograph final | 2016-04-08 |
| terconazole | New Drug Application | 2025-09-08 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| mycoses | — | D009181 | B35-B49 |
| vulvovaginal candidiasis | EFO_0007543 | D002181 | B37.3 |
Agency Specific
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Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Candidiasis | D002177 | — | B37 | — | — | — | — | 1 | 1 |
| Vulvovaginal candidiasis | D002181 | EFO_0007543 | B37.3 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Terconazole |
| INN | terconazole |
| Description | Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It has a relatively broad spectrum compared to azole compounds but not triazole compounds. Testing shows that it is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis.
|
| Classification | Small molecule |
| Drug class | systemic antifungals (miconazole type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)N1CCN(c2ccc(OC[C@H]3CO[C@](Cn4cncn4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 172587-59-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1306 |
| ChEBI ID | 82980 |
| PubChem CID | 441383 |
| DrugBank | DB00251 |
| UNII ID | 0KJ2VE664U (ChemIDplus, GSRS) |
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Estimated US medical usage
Terconazole
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PubMed Central
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Additional graphs summarizing 590 documents
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Safety
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Adverse Events
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299 adverse events reported
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