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AboutPricing
Drug ReportsTeneligliptin
Teneligliptin
Teneligliptin is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against dipeptidyl peptidase 4. In addition, it is known to target dipeptidyl peptidase 8 and dipeptidyl peptidase 9.
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Target
Variants
Financial
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A10: Drugs used in diabetes
— A10B: Blood glucose lowering drugs, excl. insulins
— A10BH: Dipeptidyl peptidase 4 (dpp-4) inhibitors for blood glucose lowering
— A10BH08: Teneligliptin
HCPCS
No data
Clinical
Clinical Trials
37 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 2 diabetes mellitusD003924EFO_0001360E11—2111—14
Insulin resistanceD007333EFO_0002614E88.819—131—5
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Diabetes mellitusD003920EFO_0000400E08-E13—14——5
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTeneligliptin
INNteneligliptin
Description
Teneligliptin is an amino acid amide.
Classification
Small molecule
Drug classdipeptidyl aminopeptidase-IV inhibitors
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Cc1cc(N2CCN([C@@H]3CN[C@H](C(=O)N4CCSC4)C3)CC2)n(-c2ccccc2)n1
Identifiers
PDB—
CAS-ID760937-92-6
RxCUI—
ChEMBL IDCHEMBL2147777
ChEBI ID—
PubChem CID11949652
DrugBank—
UNII ID28ZHI4CF9C (ChemIDplus, GSRS)
Target
Agency Approved
DPP4
DPP4
Organism
Homo sapiens
Gene name
DPP4
Gene synonyms
ADCP2, CD26
NCBI Gene ID
1803
Protein name
dipeptidyl peptidase 4
Protein synonyms
ADABP, ADCP-2, Adenosine deaminase complexing protein 2, CD26, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP IV, Gly-Pro naphthylamidase, Post-proline dipeptidyl aminopeptidase IV, T-cell activation antigen CD26, TP103, Xaa-Pro-dipeptidylaminopeptidase
Uniprot ID
Q53TN1
Mouse ortholog
Dpp4 (13482)
dipeptidyl peptidase 4 (Q3U514)
Alternate
DPP8
DPP8
DPP9
DPP9
Organism
Homo sapiens
Gene name
DPP8
Gene synonyms
DPRP1
NCBI Gene ID
54878
Protein name
dipeptidyl peptidase 8
Protein synonyms
Dipeptidyl peptidase IV-related protein 1, Dipeptidyl peptidase VIII, DPP VIII, DPRP-1, Prolyl dipeptidase DPP8
Uniprot ID
Q9NXF4
Mouse ortholog
Dpp8 (74388)
dipeptidyl peptidase 8 (Q9D4G6)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,082 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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243 adverse events reported
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