Tempol
Tempol is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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YTD
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2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Commercial
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ototoxicity | D000081015 | — | — | — | 1 | — | — | — | 1 |
| Mucositis | D052016 | EFO_1001898 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anus neoplasms | D001005 | EFO_0003835 | C21 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Tempol |
| INN | — |
| Description | 4-hydroxy-TEMPO is a member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties. It has a role as a radical scavenger, a catalyst, a nephroprotective agent, an anti-inflammatory agent, a neuroprotective agent, a hepatoprotective agent, an antineoplastic agent and an apoptosis inducer. It is a member of aminoxyls and a hydroxypiperidine. It is functionally related to a TEMPO. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)CC(O)CC(C)(C)N1[O] |
Identifiers
| PDB | — |
| CAS-ID | 2226-96-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL607023 |
| ChEBI ID | — |
| PubChem CID | 137994 |
| DrugBank | DB12449 |
| UNII ID | — |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,932 adverse events reported
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