Ketek(telithromycin)
Ketek, Levviax (telithromycin) is a small molecule pharmaceutical. Telithromycin was first approved as Ketek on 2001-07-09. It is used to treat bacterial infections in the USA. It has been approved in Europe to treat bacterial pneumonia, chronic bronchitis, community-acquired infections, pharyngitis, and pneumonia amongst others.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Trade Name
FDA
EMA
No data
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| ketek | New Drug Application | 2012-05-02 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| bacterial infections | — | D001424 | A49 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
26 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pneumonia | D011014 | EFO_0003106 | — | — | 1 | 1 | 5 | — | 7 |
| Chronic bronchitis | D029481 | — | J42 | — | — | — | 6 | — | 6 |
| Bronchitis | D001991 | — | J40 | — | — | — | 6 | — | 6 |
| Acute disease | D000208 | — | — | — | — | — | 3 | — | 3 |
| Respiratory tract infections | D012141 | — | J06.9 | — | — | — | 3 | — | 3 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | 1 | 2 | — | 3 |
| Infections | D007239 | EFO_0000544 | — | — | — | 1 | 2 | — | 3 |
| Healthy volunteers/patients | — | — | — | — | — | — | 2 | — | 2 |
| Maxillary sinusitis | D015523 | EFO_0007361 | J32.0 | — | — | 1 | 1 | — | 2 |
| Communicable diseases | D003141 | — | — | — | — | 1 | 1 | — | 2 |
Show 2 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Otitis media | D010033 | EFO_0004992 | H66.9 | — | — | 3 | — | — | 3 |
| Otitis | D010031 | — | — | — | — | 3 | — | — | 3 |
| Pharyngitis | D010612 | — | R07.0 | — | — | 2 | — | — | 2 |
| Tonsillitis | D014069 | HP_0011110 | J03 | — | — | 2 | — | — | 2 |
| Suppurative otitis media | D010035 | EFO_0007503 | H66 | — | — | 1 | — | — | 1 |
| Suppuration | D013492 | — | — | — | — | 1 | — | — | 1 |
| Scrub typhus | D012612 | EFO_0007480 | A75.3 | — | — | 1 | — | — | 1 |
| Epidemic louse-borne typhus | D014438 | EFO_0007182 | A75 | — | — | 1 | — | — | 1 |
| Asthma | D001249 | EFO_0000270 | J45 | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 1 | 1 |
| Chemical and drug induced liver injury | D056486 | EFO_0004228 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Telithromycin |
| INN | telithromycin |
| Description | Telithromycin is the first ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek. It is used to treat community acquired pneumonia of mild to moderate severity. After significant safety concerns, the US Food and Drug Administration sharply curtailed the approved uses of the drug in early 2007.
|
| Classification | Small molecule |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@H]1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCCn3cnc(-c4cccnc4)c3)C(=O)O[C@]12C |
Identifiers
| PDB | — |
| CAS-ID | 191114-48-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1136 |
| ChEBI ID | — |
| PubChem CID | 5462516 |
| DrugBank | DB00976 |
| UNII ID | KI8H7H19WL (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Telithromycin
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 2,731 documents
View more details
Safety
Black-box Warning
Black-box warning for: Ketek
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
4,471 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use