Teicoplanin
Teicoplanin is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
43 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | 3 | 6 | 10 |
| Communicable diseases | D003141 | — | — | — | — | — | 1 | 4 | 5 |
| Staphylococcal infections | D013203 | — | A49.01 | — | — | — | 1 | 3 | 4 |
| Surgical wound infection | D013530 | — | — | — | — | 1 | 2 | — | 3 |
| Bacterial infections | D001424 | — | A49 | — | — | — | 1 | 2 | 3 |
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | — | — | 1 | 1 | 2 |
| Febrile neutropenia | D064147 | — | — | — | — | — | 1 | 1 | 2 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | 1 | — | 1 |
| Surgical amputation | D000671 | — | — | — | — | — | 1 | — | 1 |
| Wound infection | D014946 | — | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infectious skin diseases | D012874 | — | — | — | — | 1 | — | 2 | 3 |
| Soft tissue infections | D018461 | — | — | — | — | 1 | — | 1 | 2 |
| Osteomyelitis | D010019 | EFO_0003102 | M86 | — | 1 | 1 | — | — | 2 |
| Scoliosis | D012600 | EFO_0004273 | M41 | — | — | 1 | — | — | 1 |
| Spinal stenosis | D013130 | EFO_0007490 | M48.0 | — | — | 1 | — | — | 1 |
| Spondylolisthesis | D013168 | EFO_0007493 | M43.1 | — | — | 1 | — | — | 1 |
| Intervertebral disc displacement | D007405 | EFO_1001800 | — | — | — | 1 | — | — | 1 |
| Diabetic foot | D017719 | EFO_1001459 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteoarticular tuberculosis | D014394 | EFO_0007487 | A18.0 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neurosurgical procedures | D019635 | — | — | 1 | — | — | — | — | 1 |
| Fibrosis | D005355 | — | — | 1 | — | — | — | — | 1 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | — | — | — | 3 | 3 |
| Critical illness | D016638 | — | — | — | — | — | — | 2 | 2 |
| Infectious arthritis | D001170 | EFO_1001351 | M00 | — | — | — | — | 2 | 2 |
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 2 | 2 |
| Enterococcus | D016983 | — | — | — | — | — | — | 2 | 2 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 2 | 2 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 2 | 2 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 1 | 1 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | — | 1 | 1 |
| Prosthesis-related infections | D016459 | EFO_1001406 | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Teicoplanin |
| INN | teicoplanin |
| Description | Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. It is a semisynthetic glycopeptide antibiotic with a spectrum of activity similar to vancomycin. Its mechanism of action is to inhibit bacterial cell wall synthesis.
|
| Classification | Unknown |
| Drug class | antibacterials (Actinoplanes strains) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)N[C@@H]1[C@H](Oc2c3cc4cc2Oc2ccc(cc2Cl)[C@@H](O[C@@H]2O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]2NC(C)=O)[C@@H]2NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H]4NC(=O)[C@@H](Cc5ccc(c(Cl)c5)O3)NC(=O)[C@H](N)c3ccc(O)c(c3)Oc3cc(O)cc4c3)c3ccc(O)c(c3)-c3c(O[C@H]4O[C@H](CO)[C@@H](O)[C@@H](O)[C@@H]4O)cc(O)cc3[C@@H](C(=O)O)NC2=O)O[C@@H](CO)[C@@H](O)[C@@H]1O |
Identifiers
| PDB | — |
| CAS-ID | 61036-62-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297166 |
| ChEBI ID | — |
| PubChem CID | 16129712 |
| DrugBank | DB06149 |
| UNII ID | 4U3D3YY81M (ChemIDplus, GSRS) |
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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3,185 adverse events reported
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