Therapeutic Area | MeSH |
---|---|
skin and connective tissue diseases | D017437 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TAZORAC | Allergan | N-021184 RX | 2000-09-29 | 2 products, RLD, RS |
AVAGE | Allergan | N-021184 RX | 2002-09-30 | 1 products, RLD, RS |
TAZORAC | Allergan | N-020600 RX | 1997-06-13 | 2 products, RLD, RS |
ARAZLO | Bausch Health Companies | N-211882 RX | 2019-12-18 | 1 products, RLD, RS |
FABIOR | Mayne Group | N-202428 RX | 2012-05-11 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
DUOBRII | Bausch Health Companies | N-209354 RX | 2019-04-25 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
011312 niacinamide 4% / tazarotene 0.05% | unapproved drug other | 2020-07-02 |
arazlo | New Drug Application | 2023-09-26 |
clindamycin 1% / niacinamide 2% / tazarotene 0.05% | unapproved drug other | 2019-05-09 |
duobrii | New Drug Application | 2020-01-01 |
fabior | New Drug Application | 2024-05-09 |
hyaluronic acid sodium salt 0.5% / tazarotene 0.05% | unapproved drug other | 2019-05-09 |
hyaluronic acid sodium salt 0.5% / tazarotene 0.1% | unapproved drug other | 2019-05-06 |
niacinamide 4% / tazarotene 0.05% | unapproved drug other | 2019-04-23 |
niacinamide 4% / tazarotene 0.1% | unapproved drug other | 2019-05-09 |
tazarodex | C200263 | 2023-12-21 |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Tazarotene, Arazlo, Bausch | |||
11311482 | 2038-05-11 | U-2368 | |
11679116 | 2036-06-06 | DP | |
Halobetasol Propionate / Tazarotene, Duobrii, Bausch | |||
10251895 | 2036-06-06 | DP | |
10426787 | 2036-06-06 | U-2625 | |
11648256 | 2036-06-06 | DP | U-2625 |
11679115 | 2036-06-06 | DP | U-2625 |
8809307 | 2031-11-02 | DP | |
10478502 | 2031-11-02 | DP | U-2625 |
11839656 | 2031-11-02 | U-2625 | |
Tazarotene, Fabior, Mayne Pharma | |||
8808716 | 2030-02-24 | DP | |
10568859 | 2030-02-24 | DP | U-2760 |
10688071 | 2030-02-24 | DP | U-2760 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Acne vulgaris | D000152 | EFO_0003894 | L70 | 1 | — | 1 | 3 | — | 5 |
Drug common name | Tazarotene |
INN | tazarotene |
Description | Tazarotene is the ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin. It has a role as a keratolytic drug, a prodrug and a teratogenic agent. It is a retinoid, a thiochromane, a member of pyridines, an acetylenic compound and an ethyl ester. It is functionally related to a tazarotenic acid. |
Classification | Small molecule |
Drug class | arotinoid derivatives |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3)nc1 |
PDB | — |
CAS-ID | 118292-40-3 |
RxCUI | — |
ChEMBL ID | CHEMBL1657 |
ChEBI ID | 32184 |
PubChem CID | 5381 |
DrugBank | DB00799 |
UNII ID | 81BDR9Y8PS (ChemIDplus, GSRS) |