Tariquidar
Tariquidar is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target ATP-dependent translocase ABCB1.
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Variants
Financial
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Events Timeline
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YTD
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2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | — | — | 2 | — | — | 2 |
| Lung neoplasms | D008175 | — | C34.90 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Tariquidar |
| INN | tariquidar |
| Description | Tariquidar is a member of benzamides. |
| Classification | Small molecule |
| Drug class | multidrug resistance inhibitors: quinoline derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3cc(OC)c(OC)cc3NC(=O)c3cnc4ccccc4c3)cc1)CC2 |
Identifiers
| PDB | — |
| CAS-ID | 206873-63-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL348475 |
| ChEBI ID | — |
| PubChem CID | 148201 |
| DrugBank | DB06240 |
| UNII ID | J58862DTVD (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ABCB1
ABCB1
Organism
Homo sapiens
Gene name
ABCB1
Gene synonyms
MDR1, PGY1
NCBI Gene ID
Protein name
ATP-dependent translocase ABCB1
Protein synonyms
ATP-binding cassette sub-family B member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, CD243, colchicin sensitivity, doxorubicin resistance, Multidrug resistance protein 1, P-glycoprotein 1, Phospholipid transporter ABCB1
Uniprot ID
Mouse ortholog
Abcb1b (18669)
ATP-dependent translocase ABCB1 (P06795)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,718 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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18 adverse events reported
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