Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | 4 | 17 | — | — | 21 |
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | 3 | 7 | — | — | 10 |
Low back pain | D017116 | HP_0003419 | M54.5 | 1 | 3 | 3 | — | — | 7 |
Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | 1 | 5 | — | — | 6 |
Arthritis | D001168 | HP_0001369 | M05-M14 | — | 1 | 5 | — | — | 6 |
Back pain | D001416 | HP_0003418 | M54 | — | 3 | 2 | — | — | 5 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 2 | 1 | — | — | 3 |
Cancer pain | D000072716 | — | G89.3 | — | — | 2 | — | — | 2 |
Pain | D010146 | EFO_0003843 | R52 | — | 1 | 1 | — | — | 2 |
Chronic pain | D059350 | HP_0012532 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Interstitial cystitis | D018856 | EFO_1000869 | N30.1 | 1 | 2 | — | — | — | 3 |
Cystitis | D003556 | EFO_1000025 | N30 | 1 | 2 | — | — | — | 3 |
Peripheral nervous system diseases | D010523 | HP_0009830 | G64 | — | 1 | — | — | — | 1 |
Diabetic neuropathies | D003929 | EFO_1000783 | — | — | 1 | — | — | — | 1 |
Skin neoplasms | D012878 | EFO_0004198 | C44 | — | 1 | — | — | — | 1 |
Neurofibromatoses | D017253 | — | Q85.00 | — | 1 | — | — | — | 1 |
Neurilemmoma | D009442 | EFO_0000693 | — | — | 1 | — | — | — | 1 |
Pancreatitis | D010195 | HP_0001733 | K85 | — | 1 | — | — | — | 1 |
Chronic pancreatitis | D050500 | EFO_0000342 | K86.1 | — | 1 | — | — | — | 1 |
Neoplasms | D009369 | — | C80 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Spine osteoarthritis | D055013 | EFO_1000787 | — | 1 | — | — | — | — | 1 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Drug common name | Tanezumab |
INN | tanezumab |
Description | Tanezumab (humanized mab) |
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | >4EDW:H|tanezumab Fab heavy chain
QVQLQESGPGLVKPSETLSLTCTVSGFSLIGYDLNWIRQPPGKGLEWIGIIWGDGTTDYNSAVKSRVTISKDTSKNQFSL
KLSSVTAADTAVYYCARGGYWYATSYYFDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKTSHHHHHHG
>4EDW:L|tanezumab Fab light chain
DIQMTQSPSSLSASVGDRVTITCRASQSISNNLNWYQQKPGKAPKLLIYYTSRFHSGVPSRFSGSGSGTDFTFTISSLQP
EDIATYYCQQEHTLPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
PDB | 4EDW |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL2108567 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB12335 |
UNII ID | EQL0E9GCX1 (ChemIDplus, GSRS) |