Tradename | Company | Number | Date | Products |
---|---|---|---|---|
SOLTAMOX | MAYNE PHARMA COMMRCL | N-021807 RX | 2005-10-29 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
soltamox | New Drug Application | 2021-11-29 |
tamoxifen citrate | ANDA | 2024-01-30 |
Code | Description |
---|---|
S0187 | Tamoxifen citrate, oral, 10 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 30 | 136 | 127 | 13 | 80 | 375 |
Hot flashes | D019584 | — | — | 1 | 3 | 1 | 1 | 3 | 9 |
Invasive hydatidiform mole | D002820 | — | D39.2 | 1 | 1 | 2 | 1 | 1 | 6 |
Infertility | D007246 | HP_0000789 | — | — | — | 1 | 1 | 1 | 3 |
Metrorrhagia | D008796 | HP_0100608 | N92.1 | — | — | — | 2 | — | 2 |
Menstruation disturbances | D008599 | HP_0400007 | N91.5 | — | — | — | 1 | — | 1 |
Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | 1 | — | 1 |
Medicated intrauterine devices | D007436 | — | — | — | — | — | 1 | — | 1 |
Pharmacokinetics | D010599 | — | — | — | — | — | 1 | — | 1 |
Sexuality | D019529 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Male breast neoplasms | D018567 | — | — | 1 | 9 | 6 | — | 4 | 20 |
Neoplasms | D009369 | — | C80 | 4 | 4 | 2 | — | 2 | 12 |
Triple negative breast neoplasms | D064726 | — | — | 2 | 7 | 2 | — | — | 11 |
Endometrial neoplasms | D016889 | EFO_0004230 | — | — | 2 | 2 | — | 5 | 9 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 5 | 1 | — | — | 8 |
Ductal carcinoma breast | D018270 | — | — | 1 | 3 | 2 | — | 1 | 7 |
Osteoporosis | D010024 | HP_0000939 | M81.0 | — | — | 3 | — | 3 | 6 |
Fallopian tube neoplasms | D005185 | — | — | — | 2 | 2 | — | — | 4 |
Intraductal carcinoma noninfiltrating | D002285 | — | D05.1 | — | 2 | 1 | — | 1 | 4 |
Prostatic neoplasms | D011471 | — | C61 | — | 2 | 2 | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Central nervous system neoplasms | D016543 | — | — | — | 5 | — | — | — | 5 |
Urinary bladder neoplasms | D001749 | — | C67 | — | 3 | — | — | — | 3 |
Amyotrophic lateral sclerosis | D000690 | HP_0007354 | G12.21 | 1 | 3 | — | — | — | 3 |
Arthralgia | D018771 | HP_0002829 | M25.5 | — | 1 | — | — | 2 | 3 |
Covid-19 | D000086382 | — | U07.1 | — | 2 | — | — | — | 2 |
Glioblastoma | D005909 | EFO_0000515 | — | 1 | 1 | — | — | — | 2 |
Sarcoma | D012509 | — | — | — | 1 | — | — | 1 | 2 |
Pulmonary arterial hypertension | D000081029 | — | — | — | 2 | — | — | — | 2 |
Urologic neoplasms | D014571 | — | C64-C68 | — | 1 | — | — | — | 1 |
Glioma | D005910 | EFO_0000520 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | — | — | 2 | 3 |
Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 1 | — | — | — | — | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
Gastrointestinal neoplasms | D005770 | — | C26.9 | 1 | — | — | — | — | 1 |
Barrett esophagus | D001471 | EFO_0000280 | K22.7 | 1 | — | — | — | — | 1 |
Aggressive fibromatosis | D018222 | — | D48.11 | 1 | — | — | — | — | 1 |
Osteosarcoma | D012516 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 2 | 2 |
Postmenopause | D017698 | — | — | — | — | — | — | 2 | 2 |
Hodgkin disease | D006689 | — | C81 | — | — | — | — | 2 | 2 |
Endometrial hyperplasia | D004714 | — | N85.0 | — | — | — | — | 2 | 2 |
Systemic mastocytosis | D034721 | — | C96.21 | — | — | — | — | 1 | 1 |
Non-small-cell lung carcinoma | D002289 | — | — | — | — | — | — | 1 | 1 |
Depression | D003863 | — | F33.9 | — | — | — | — | 1 | 1 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | — | — | 1 | 1 |
Fertility | D005298 | — | — | — | — | — | — | 1 | 1 |
Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | — | 1 | 1 |
Drug common name | Tamoxifen |
INN | tamoxifen |
Description | Tamoxifen is a tertiary amino compound and a stilbenoid. It has a role as an estrogen receptor antagonist, a bone density conservation agent, an estrogen receptor modulator, an estrogen antagonist, an angiogenesis inhibitor, an EC 2.7.11.13 (protein kinase C) inhibitor, an EC 1.2.3.1 (aldehyde oxidase) inhibitor and an antineoplastic agent. It derives from a hydride of a stilbene. |
Classification | Small molecule |
Drug class | Selective estrogen receptor modulator |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 |
PDB | — |
CAS-ID | 10540-29-1 |
RxCUI | — |
ChEMBL ID | CHEMBL83 |
ChEBI ID | 41774 |
PubChem CID | 2733526 |
DrugBank | DB00675 |
UNII ID | 094ZI81Y45 (ChemIDplus, GSRS) |