Talfirastide
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | 6 | 4 | — | 4 | 3 | 17 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 4 | 2 | — | 1 | — | 7 |
| Heart failure | D006333 | EFO_0003144 | I50 | 1 | 2 | — | 3 | 1 | 6 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 1 | 1 | 2 | — | 4 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | 2 | 1 | 3 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | — | 1 | — | 3 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | 1 | 2 | — | 3 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | 1 | 1 | 2 |
| Cardiotoxicity | D066126 | EFO_1001482 | — | — | 1 | — | 1 | — | 2 |
| White coat hypertension | D059466 | — | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | 2 | 5 | 2 | — | 3 | 10 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | 1 | 4 | 2 | — | — | 4 |
| Infections | D007239 | EFO_0000544 | — | 1 | 3 | 1 | — | — | 3 |
| Cardiomyopathies | D009202 | EFO_0000318 | I42 | — | 3 | 1 | — | — | 3 |
| Hypertrophy | D006984 | EFO_0002460 | — | — | 2 | 1 | — | 1 | 3 |
| Communicable diseases | D003141 | — | — | — | 2 | 1 | — | — | 2 |
| Respiratory insufficiency | D012131 | — | J96.9 | 1 | 2 | 1 | — | — | 2 |
| Hypertrophic cardiomyopathy | D002312 | EFO_0000538 | I42.1 | — | 2 | 1 | — | — | 2 |
| Ischemic stroke | D000083242 | — | — | — | 1 | 1 | — | — | 2 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | 1 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Essential hypertension | D000075222 | — | I10 | 1 | 2 | — | — | 1 | 4 |
| Acute lung injury | D055371 | EFO_0004610 | — | — | 1 | — | — | 2 | 3 |
| Syndrome | D013577 | — | — | 1 | 1 | — | — | 1 | 3 |
| Hematologic neoplasms | D019337 | — | — | — | 3 | — | — | — | 3 |
| Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | — | 1 | — | — | 1 | 2 |
| Newborn respiratory distress syndrome | D012127 | — | P22 | — | 1 | — | — | 1 | 2 |
| Cognitive dysfunction | D060825 | — | G31.84 | — | 2 | — | — | — | 2 |
| Inflammation | D007249 | MP_0001845 | — | 1 | 1 | — | — | — | 2 |
| Psychological stress | D013315 | — | — | 1 | 2 | — | — | — | 2 |
| Graft vs host disease | D006086 | — | D89.81 | — | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | 1 | — | — | — | 1 | 2 |
| Myelodysplastic syndromes | D009190 | — | D46 | 2 | — | — | — | — | 2 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | 1 | — | — | — | — | 1 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | 1 | — | — | — | — | 1 |
| Barrett esophagus | D001471 | EFO_0000280 | K22.7 | 1 | — | — | — | — | 1 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 1 | — | — | — | — | 1 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
| Pure autonomic failure | D054970 | — | — | 1 | — | — | — | — | 1 |
| Shy-drager syndrome | D012791 | EFO_1001050 | — | 1 | — | — | — | — | 1 |
Show 14 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pre-eclampsia | D011225 | EFO_0000668 | O14 | — | — | — | — | 1 | 1 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | — | 1 | 1 |
| Eclampsia | D004461 | — | O15 | — | — | — | — | 1 | 1 |
| Left ventricular hypertrophy | D017379 | EFO_0003896 | — | — | — | — | — | 1 | 1 |
| Hypophosphatemia | D017674 | HP_0002148 | — | — | — | — | — | 1 | 1 |
| Familial hypophosphatemic rickets | D053098 | — | — | — | — | — | — | 1 | 1 |
| Renin-angiotensin system | D012084 | — | — | — | — | — | — | 1 | 1 |
| Pediatric obesity | D063766 | — | — | — | — | — | — | 1 | 1 |
| Lung injury | D055370 | — | S27.30 | — | — | — | — | 1 | 1 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | — |
| INN | — |
| Description | — |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | — |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
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