Talabostat
Talabostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target dipeptidyl peptidase 8, dipeptidyl peptidase 4, and dipeptidyl peptidase 9.
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Commercial
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Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | — | C34.90 | — | 1 | 2 | — | — | 3 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | — | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Skin neoplasms | D012878 | EFO_0004198 | C44 | — | 2 | — | — | — | 2 |
| Melanoma | D008545 | — | — | — | 2 | — | — | — | 2 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | — | 1 | — | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | — | 1 |
| Adenocarcinoma | D000230 | — | — | — | 1 | — | — | — | 1 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Talabostat |
| INN | talabostat |
| Description | Talabostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target dipeptidyl peptidase 8, dipeptidyl peptidase 4, and dipeptidyl peptidase 9. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |
Identifiers
| PDB | — |
| CAS-ID | 149682-77-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL67279 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | KZ1O2SH88Z (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
DPP8
DPP8
DPP4
DPP4
DPP9
DPP9
Variants
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PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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