TESOFENSINE
Tesofensine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
14 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | 5 | — | — | — | 5 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 3 | — | — | — | 3 |
| Prader-willi syndrome | D011218 | Orphanet_739 | Q87.11 | — | 2 | — | — | — | 2 |
| Syndrome | D013577 | — | — | — | 2 | — | — | — | 2 |
| Weight loss | D015431 | — | — | — | 1 | — | — | — | 1 |
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | — | — | — | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | — | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 1 | — | — | — | 1 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 1 | — | — | — | 1 |
| Dementia | D003704 | EFO_0003862 | F03 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | TESOFENSINE |
| INN | tesofensine |
| Description | Tesofensine (NS2330) is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity. Tesofensine was originally developed by a Danish biotechnology company, NeuroSearch, who transferred the rights to Saniona in 2014.
|
| Classification | Small molecule |
| Drug class | norepinephrine, serotonin, dopamine, reuptake inhibitor |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCOC[C@@H]1[C@@H](c2ccc(Cl)c(Cl)c2)C[C@@H]2CC[C@H]1N2C |
Identifiers
| PDB | — |
| CAS-ID | 195875-84-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3989690 |
| ChEBI ID | — |
| PubChem CID | 11370864 |
| DrugBank | — |
| UNII ID | BLH9UKX9V1 (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Additional graphs summarizing 219 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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