TALAMPANEL
Talampanel is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target glutamate receptor 2.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
No data
Clinical
Clinical Trials
12 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | 1 | — | — | — | 3 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 1 | 3 | — | — | — | 3 |
| Dyskinesias | D020820 | HP_0002310 | G24 | 1 | 2 | — | — | — | 2 |
| Glioblastoma | D005909 | EFO_0000515 | — | — | 2 | — | — | — | 2 |
| Amyotrophic lateral sclerosis | D000690 | HP_0007354 | G12.21 | — | 2 | — | — | — | 2 |
| Motor neuron disease | D016472 | EFO_0003782 | G12.2 | — | 2 | — | — | — | 2 |
| Movement disorders | D009069 | HP_0100022 | — | 1 | 1 | — | — | — | 1 |
| Sclerosis | D012598 | — | — | — | 1 | — | — | — | 1 |
| Glioma | D005910 | EFO_0000520 | — | — | 1 | — | — | — | 1 |
| Central nervous system neoplasms | D016543 | — | — | — | 1 | — | — | — | 1 |
Show 5 more
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | TALAMPANEL |
| INN | talampanel |
| Description | Talampanel is a member of benzodioxoles. |
| Classification | Small molecule |
| Drug class | ionotropic non-NMDA (N-methyl D-aspartate) glutamate receptors [AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) and/or KA (kainite antagonist) receptors]: antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2C[C@H]1C)OCO3 |
Identifiers
| PDB | — |
| CAS-ID | 161832-65-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL61872 |
| ChEBI ID | 34992 |
| PubChem CID | 164509 |
| DrugBank | — |
| UNII ID | CVS43XG1L5 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
GRIA2
GRIA2
Organism
Homo sapiens
Gene name
GRIA2
Gene synonyms
GluA2, GLUR2
NCBI Gene ID
Protein name
glutamate receptor 2
Protein synonyms
AMPA receptor subunit GluA2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 2
Uniprot ID
Mouse ortholog
Gria2 (14800)
glutamate receptor 2 (Q9D6D3)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 311 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use